Liquid Chromatographic Fluorescence Method for the Determination of Thiabendazole Residues in Green Bananas and Banana Pulp

1994 ◽  
Vol 77 (3) ◽  
pp. 710-713 ◽  
Author(s):  
Rene V Arenas ◽  
Nelson A Johnson
Keyword(s):  
Column Liquid Chromatography ◽  
Cation Exchange ◽  
Chromatographic Method ◽  
Solid Phase ◽  
Extraction Column ◽  
Phase Extraction ◽  
Liquid Chromatographic Method ◽  
Cation Exchange Column ◽  
Liquid Chromatographic

Abstract A novel liquid chromatographic method was developed for the determination of thiabendazole (TBZ) residues in whole green bananas and ripe banana pulp. TBZ is extracted from the banana matrix with ethyl acetate, followed by cleanup of extract on a cation-exchange, solid-phase extraction column. The extract is analyzed for TBZ residues by column liquid chromatography using a cation-exchange column with fluorescence detection. Recoveries of TBZ from whole green bananas fortified with TBZ at 0.05-10 ppm and from ripe banana pulp fortified with TBZ at 0.01-2 ppm averaged 93 and 95%, respectively. The following method for monitoring TBZ residues in whole green bananas and ripe banana pulp is simple, rapid, and sensitive.

scholarly journals Determination of Nitroimidazoles and Their Metabolites in Swine Tissues by Liquid Chromatography

2003 ◽  
Vol 86 (3) ◽  
pp. 505-509 ◽  
Author(s):  
Jianzhong Shen ◽  
Yue Yhang ◽  
Suxia Zhang ◽  
Shuangyang Ding ◽  
Xinhua Xiang
Keyword(s):  
Chromatographic Method ◽  
Solid Phase ◽  
Liquid Extraction ◽  
Phase Extraction ◽  
Liquid Liquid Extraction ◽  
Liquid Chromatographic Method ◽  
Swine Tissue ◽  
Liquid Chromatographic ◽  
Sensitive Method

Abstract A liquid chromatographic method was developed for determination of metronidazole (MNZ), ronidazole (RNZ), dimetridazole (DMZ), and 2-hydroxymethyl-1-methyl-5-nitroimidazole (DMZOH) in swine tissue. After extraction with ethyl acetate and evaporation, the nitroimidazoles were redissolved in hydrochloric acid. Hexane was used in the liquid–liquid extraction to remove fat. An Oasis® HLB solid-phase extraction was performed after neutralization of the acidic extract. The limits of detection were 1.0–2.0 μg/kg for DMZOH, MNZ, RNZ, and DMZ in muscle and liver. Average recoveries ranged from 80.1 to 83.9% in muscle fortified at 10, 20, and 50 μg/kg; average re-coveries in liver ranged from 78.9 to 82.3%. The procedure provides a simple and sensitive method for monitoring DMZOH, MNZ, RNZ, and DMZ residues in swine tissues.

Sign in / Sign up

Export Citation Format

Share Document