scholarly journals Screening Procedure for Detection of Antidepressants of the Selective Serotonin Reuptake Inhibitor Type and their Metabolites in Urine as Part of a Modified Systematic Toxicological Analysis Procedure using Gas Chromatography-Mass Spectrometry*

2000 ◽  
Vol 24 (5) ◽  
pp. 340-347 ◽  
Author(s):  
Hans H. Maurer ◽  
Joerg Bickeboeller-Friedrich
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Selective Serotonin Reuptake Inhibitor ◽  
Reuptake Inhibitor ◽  
Serotonin Reuptake ◽  
Analysis Procedure ◽  
Gas Chromatography Mass Spectrometry ◽  
Toxicological Analysis ◽  
Systematic Toxicological Analysis ◽  
Inhibitor Type

scholarly journals Systematic toxicological analysis of Indian herbal ready-to-chew pouches by gas chromatography mass spectrometry

2011 ◽  
Vol 23 (4) ◽  
pp. 205-210 ◽  
Author(s):  
Maria Concetta Rotolo ◽  
Manuela Pellegrini ◽  
Devasish Bose ◽  
Emilia Marchei ◽  
Abhilasha Durgbanshi ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Gas Chromatography Mass Spectrometry ◽  
Toxicological Analysis ◽  
Systematic Toxicological Analysis ◽  
Chromatography Mass Spectrometry

Systematic toxicological analysis using liquid chromatography-mass spectrometry: techniques and inter-instrument reproducibility of mass spectra/Systematisch-toxikologische Analyse mittels Hochleistungsflüssigchromatographie-Massenspektrometrie: Techniken und Reproduzierbarkeit von Massenspektren zwischen Instrumenten

2012 ◽  
Vol 36 (2) ◽  
Author(s):  
Frank T. Peters ◽  
Dirk K. Wissenbach
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Mass Spectra ◽  
Forensic Toxicology ◽  
Gas Chromatography Mass Spectrometry ◽  
Reference Library ◽  
Toxicological Analysis ◽  
Systematic Toxicological Analysis ◽  
Chromatography Mass Spectrometry ◽  
Universal Reference

AbstractThe so-called systematic toxicological analysis (STA) aiming at simultaneous analysis of as many toxicologically relevant compounds in biosamples as possible is an important part of routine analysis in clinical and forensic toxicology. Gas chromatography-mass spectrometry and liquid chromatography with diode array detection have been the most widely used techniques for this purpose. However, in recent years STA methods based on liquid chromatography coupled to mass spectrometry (LC-MS) or tandem mass spectrometry (LC-MS/MS) have become increasingly important, although their widespread use is still hampered by the lack of a universal reference library of mass spectra that can be used on all major instrument platforms. In this review, LC-MS(/MS) methods for STA in urine and/or blood published in the past 6 years will be compared and discussed with regard to sample preparation, separation, instrument types used for mass spectrometric detection, and method validation. In addition, different approaches to achieving the goal of a universal reference library will be summarized.

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