Characterization of Malaria Transmission by Anopheles (Diptera: Culicidae) in Western Kenya in Preparation for Malaria Vaccine Trials

1990 ◽  
Vol 27 (4) ◽  
pp. 570-577 ◽  
Author(s):  
John C. Beier ◽  
Peter V. Perkins ◽  
Fred K. Onyango ◽  
Thomas P. Gargan ◽  
Charles N. Oster ◽  
...  
Keyword(s):  
Malaria Transmission ◽  
Malaria Vaccine ◽  
Western Kenya ◽  
Vaccine Trials

scholarly journals Sustainability of Reductions in Malaria Transmission and Infant Mortality in Western Kenya With Use of Insecticide-Treated Bednets

JAMA ◽  
2004 ◽  
Vol 291 (21) ◽  
pp. 2571 ◽  
Author(s):  
Kim A. Lindblade ◽  
Thomas P. Eisele ◽  
John E. Gimnig ◽  
Jane A. Alaii ◽  
Frank Odhiambo ◽  
...  
Keyword(s):  
Infant Mortality ◽  
Malaria Transmission ◽  
Western Kenya

scholarly journals Molecular Characterization of the CytochromebGene andIn VitroAtovaquone Susceptibility of Plasmodium falciparum Isolates from Kenya

2015 ◽  
Vol 59 (3) ◽  
pp. 1818-1821 ◽  
Author(s):  
Luicer A. Ingasia ◽  
Hoseah M. Akala ◽  
Mabel O. Imbuga ◽  
Benjamin H. Opot ◽  
Fredrick L. Eyase ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
Genetic Polymorphism ◽  
Molecular Characterization ◽  
Mutant Allele ◽  
Inhibitory Concentration ◽  
Wild Type Allele ◽  
Wild Type ◽  
Western Kenya ◽  
Content Type

ABSTRACTThe prevalence of a genetic polymorphism(s) at codon 268 in the cytochromebgene, which is associated with failure of atovaquone-proguanil treatment, was analyzed in 227Plasmodium falciparumparasites from western Kenya. The prevalence of the wild-type allele was 63%, and that of the Y268S (denoting a Y-to-S change at position 268) mutant allele was 2%. There were no pure Y268C or Y268N mutant alleles, only mixtures of a mutant allele(s) with the wild type. There was a correlation between parasite 50% inhibitory concentration (IC50) and parasite genetic polymorphism; mutant alleles had higher IC50s than the wild type.

scholarly journals Spatial and temporal dynamics of malaria transmission in rural Western Kenya

2012 ◽  
Vol 5 (1) ◽  
pp. 86 ◽  
Author(s):  
Nyaguara Amek ◽  
Nabie Bayoh ◽  
Mary Hamel ◽  
Kim A Lindblade ◽  
John E Gimnig ◽  
...  
Keyword(s):  
Malaria Transmission ◽  
Temporal Dynamics ◽  
Western Kenya ◽  
Spatial And Temporal Dynamics

scholarly journals Characterization of Plasmodium ovale curtisi and P. ovale wallikeri in Western Kenya Utilizing a Novel Species-specific Real-time PCR Assay

2015 ◽  
Vol 9 (1) ◽  
pp. e0003469 ◽  
Author(s):  
Robin H. Miller ◽  
Clifford O. Obuya ◽  
Elizabeth W. Wanja ◽  
Bernhards Ogutu ◽  
John Waitumbi ◽  
...  
Keyword(s):  
Real Time ◽  
Real Time Pcr ◽  
Novel Species ◽  
Plasmodium Ovale ◽  
Pcr Assay ◽  
Western Kenya ◽  
Plasmodium Ovale Curtisi ◽  
Species Specific

scholarly journals Comparing ownership and use of bed nets at two sites with differential malaria transmission in western Kenya

2016 ◽  
Vol 15 (1) ◽  
Author(s):  
Kacey C. Ernst ◽  
Mary H. Hayden ◽  
Heather Olsen ◽  
Jamie L. Cavanaugh ◽  
Irene Ruberto ◽  
...  
Keyword(s):  
Malaria Transmission ◽  
Bed Nets ◽  
Western Kenya

scholarly journals Blood Stage Malaria Vaccine Eliciting High Antigen-Specific Antibody Concentrations Confers No Protection to Young Children in Western Kenya

PLoS ONE ◽  
2009 ◽  
Vol 4 (3) ◽  
pp. e4708 ◽  
Author(s):  
Bernhards R. Ogutu ◽  
Odika J. Apollo ◽  
Denise McKinney ◽  
Willis Okoth ◽  
Joram Siangla ◽  
...  
Keyword(s):  
Young Children ◽  
Specific Antibody ◽  
Malaria Vaccine ◽  
Blood Stage ◽  
Western Kenya ◽  
Blood Stage Malaria

Malaria Vaccine Trials

1999 ◽  
Vol 15 (8) ◽  
pp. 348
Author(s):  
David Walliker
Keyword(s):  
Malaria Vaccine ◽  
Vaccine Trials
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