Effect of Plasmodium yoelii nigeriensis (Haemosporidia: Plasmodiidae) on Anopheles stephensi (Diptera: Culicidae) Vitellogenesis

1998 ◽  
Vol 35 (6) ◽  
pp. 956-961 ◽  
Author(s):  
Nusrat Jahan ◽  
Hilary Hurd
PLoS ONE ◽  
2014 ◽  
Vol 9 (2) ◽  
pp. e89473 ◽  
Author(s):  
Jian Zhang ◽  
Shuguang Zhang ◽  
Yanyan Wang ◽  
Wenyue Xu ◽  
Jingru Zhang ◽  
...  

1997 ◽  
Vol 83 (4) ◽  
pp. 652 ◽  
Author(s):  
Charles B. Pumpuni ◽  
Chandana Mendis ◽  
John C. Beier

Parasitology ◽  
1995 ◽  
Vol 111 (5) ◽  
pp. 555-562 ◽  
Author(s):  
J. C. Hogg ◽  
H. Hurd

SUMMARYAnopheles stephensi mosquitoes showed a reduction in fecundity over 3 successive gonotrophic cycles, after becoming infected with Plasmodium yoelii nigeriensis. This effect could be observed at high oocyst burdens (> 75) or at low oocyst burdens (mean of 4·36). Mean bloodmeal size of the infected mosquitoes was significantly reduced only when feeding upon a mouse with a high gametocytaemia and the conversion of the bloodmeal into eggs by the infected mosquitoes was disrupted. Patterns of infected mosquito mortality, over the 3 gonotrophic cycles, varied with severity of infection. Although in 1 case increased mortality and decreased bloodmeal size may have affected fecundity, this could not have accounted for all of the observed fecundity reduction. We propose that other, unknown parasite related factors, are involved.


Parasitology ◽  
2001 ◽  
Vol 122 (5) ◽  
pp. 491-496 ◽  
Author(s):  
P. J. TAYLOR ◽  
H. HURD

Two studies were carried out to determine the effect of the rodent malaria Plasmodium yoelii nigeriensis on the blood feeding success of Anopheles stephensi. Initially, pairs of mice with similar packed cell volume (PCV) (measured by haematocrit) were selected. Following infection of one of the pair its PCV gradually fell. At various times post-infection, a comparison was made of the bloodmeal size (haemoglobin content) of mosquitoes feeding on these mice. The bloodmeal sizes increased with parasite-induced fall in PCV down to a haematocrit of 43–44%, which occurred approximately 48 h post-infection. Bloodmeals were significantly reduced, however, when mosquitoes fed on mice with higher parasitaemias and a haematocrit of 15–35%. Thus, at early stages of infection, mosquitoes ingested a bloodmeal significantly greater than did the mosquitoes feeding on the control mice. However, mosquitoes were not able to compensate for severe infection-associated anaemia. To compensate for variation due to innate differences in the mice, a second experiment was performed. Mosquitoes were fed on the same mice before (control) and after infection. Again, the bloodmeal size increased with decreasing PCV down to haematocrits of 42–45%, but declined thereafter. In this host–parasite–vector system, haematocrits that maximized erythrocyte intake were produced when gametocytes, capable of exflagellation, were present.


2013 ◽  
Vol 280 (1763) ◽  
pp. 20130711 ◽  
Author(s):  
Lauren J. Cator ◽  
Justin George ◽  
Simon Blanford ◽  
Courtney C. Murdock ◽  
Thomas C. Baker ◽  
...  

Previous studies have suggested that Plasmodium parasites can manipulate mosquito feeding behaviours such as probing, persistence and engorgement rate in order to enhance transmission success. Here, we broaden analysis of this ‘manipulation phenotype’ to consider proximate foraging behaviours, including responsiveness to host odours and host location. Using Anopheles stephensi and Plasmodium yoelii as a model system, we demonstrate that mosquitoes with early stage infections (i.e. non-infectious oocysts) exhibit reduced attraction to a human host, whereas those with late-stage infections (i.e. infectious sporozoites) exhibit increased attraction. These stage-specific changes in behaviour were paralleled by changes in the responsiveness of mosquito odourant receptors, providing a possible neurophysiological mechanism for the responses. However, we also found that both the behavioural and neurophysiological changes could be generated by immune challenge with heat-killed Escherichia coli and were thus not tied explicitly to the presence of malaria parasites. Our results support the hypothesis that the feeding behaviour of female mosquitoes is altered by Plasmodium , but question the extent to which this is owing to active manipulation by malaria parasites of host behaviour.


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