scholarly journals Primary mesenteric vein thrombosis: a case series

2020 ◽  
Vol 2020 (3) ◽  
Author(s):  
Roberto Marconato ◽  
Giulia Nezi ◽  
Giovanni Capovilla ◽  
Lucia Moletta ◽  
Nicola Baldan ◽  
...  

Abstract Mesenteric vein thrombosis (MVT) is a rare condition, often misdiagnosed due to its vague and misleading clinical presentation. It can cause intestinal infarction, peritonitis, and consequently necessitate bowel resection. CT scanning with intravenous contrast enhancement is the gold standard for its diagnosis. Radiologists have an important role in defining the extent of thrombosis and identifying any signs of intestinal infarction influencing the decision whether or not to operate. In patients with no clinical signs of peritonitis or radiological evidence of intestinal infarction, the treatment can be exclusively medical, based on full anticoagulation (initially with low molecular weight heparin, followed by vitamin K antagonists or direct acting oral-anticoagulants). The duration of medical treatment depends on radiological evidence of resolution of thrombosis and the identification of pro-coagulant risk factors.

2009 ◽  
Vol 18 (5) ◽  
pp. 422-424 ◽  
Author(s):  
Chia-Meng Chan ◽  
Wei-Lung Chen ◽  
Jiann-Hwa Chen ◽  
Yung-Lung Wu ◽  
Chien-Cheng Huang

Diagnostics ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1348
Author(s):  
Ying-Ying Chen ◽  
Sheng-Mao Wu ◽  
Russell Oliver Kosik ◽  
Yi-Chien Hsieh ◽  
Tzu-I Wu ◽  
...  

Acute abdominal pain during pregnancy is challenging, both from a diagnostic and management perspective. A non-localized, persistent pain out of proportion to physical examination is a sign that advanced imaging may be necessary. Mesenteric venous thrombosis in a pregnant patient is extremely rare, but if diagnosis is delayed, can be potentially fatal to both the mother and the fetus. We present here a pregnant patient in the tenth week of gestation with classic clinical manifestations of mesenteric vein thrombosis and the corresponding findings on magnetic resonance imaging (MRI) and computed tomography (CT).


1981 ◽  
Author(s):  
H Ludwig ◽  
H J Genz

The treatment of occlusive deep vein thrombosis during pregnancy with fibrinolytic agents as streptokinase and urokinase is still controversial. The main points of controversy are retroplacental bleeding, fetal heart rate acceleration and malformations of the fetus. The main author conducted 122 therapeutic fibrinolytic treatments during pregnancy since 1961. The earliest beginning of treatment was the 14th week, the latest the 38th week of pregnancy. The indications to all treatments in these cases was an acute thrombotic occlusion of one or both ileofemoral veins in pregnant women. The diagnosis was established by clinical signs and, since 1975 by ultrasonography (n = 63). The treatment regimen was previously designed with the use of medium large doses of streptokinase in prolongation of an initially high dosage (1000,000 IU), later on 63 cases were treated by the following scheme: Initial dosage 1.5 - 1000,000 IU streptokinase within 30 minutes i.v. by monitored infusion, followed by an hourly dosage of not more than 250,000 IU streptokinase for 24 to 48 hours. An initial raise of body temperature occured in 28% of all cases. The fetal heart rate was watched by cardiotocography so far the pregnancy was beyond the 28th week. The success rate of all cases was 72%, indicating the complete restoration of the vessel's patency, 18% responded partially, 10% did not respond at all. 55% of all cases were examined by phlebography some days after delivery, the others were checked by clinical examination only or by ultrasonography respectively. The postfibrinolytic treatment in all cases consisted in the application of heparin in the dosage of 20,000 to 40,000 IU/24 hours for at least two weeks, approximately 60 percent of the cases received oral anticoagulants for further five weeks. Complications: One premature rupture of the membranes with healthy child, one premature separation of the well situated placenta with fatal fetal outcome, two severe bleedings during the treatment which made ar. emergency delivery by cesarean section necessary. Streptokinase was then neutralized by AM- CA. No fetal malformations were observed.


Hematology ◽  
2018 ◽  
Vol 2018 (1) ◽  
pp. 399-404 ◽  
Author(s):  
Paul Monagle ◽  
Fiona Newall

Abstract Venous thrombosis (VTE) in children and neonates presents numerous management challenges. Although increasing in frequency, VTE in children and neonates is still uncommon compared with adults. The epidemiology of VTE is vastly different in neonates vs children vs adolescents vs adults. In reality, pediatric thrombosis should be viewed as a multitude of rare diseases (eg, renal vein thrombosis, spontaneous thrombosis, catheter-related thrombosis, cerebral sinovenous thrombosis), all requiring different approaches to diagnosis and with different short- and long-term consequences, but linked by the use of common therapeutic agents. Further, children have fundamentally different physiology in terms of blood flow, developmental hemostasis, and, likely, endothelial function. The American Society ofHematology 2017 Guidelines for Management of Venous Thromboembolism: Treatment of Pediatric VTE provides up-to-date evidence-based guidelines related to treatment. Therefore, this article will focus on the practical use of therapeutic agents in the management of pediatric VTE, especially unfractionated heparin, low-molecular-weight heparin, and oral vitamin K antagonists, as the most common anticoagulants used in children. Direct oral anticoagulants (DOACs) remain in clinical trials in children and should not be used outside of formal trials for the foreseeable future.


2001 ◽  
Vol 181 (1) ◽  
pp. 20-23 ◽  
Author(s):  
Celia M Divino ◽  
In Soon Park ◽  
Luz P Angel ◽  
Sharif Ellozy ◽  
Renee Spiegel ◽  
...  

Surgery ◽  
2003 ◽  
Vol 133 (2) ◽  
pp. 222-223 ◽  
Author(s):  
Stéphane Benoist ◽  
Marie-jo Laisné ◽  
Francisca Joly ◽  
Mourad Boudiaf ◽  
Yves Panis ◽  
...  

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