Houston: 1990–2008

2019 ◽  
pp. 553-590
Author(s):  
Craig A. Miller
Keyword(s):  
Hurricane Katrina ◽  
Heart Surgery ◽  
50Th Anniversary ◽  
Gold Medal ◽  
Left Ventricular ◽  
Ventricular Assist ◽  
Left Ventricular Assist ◽  
Russian President ◽  
Boris Yeltsin ◽  
Physician Scientists

The era of 1990–2008 sees the establishment of the MicroMed organization to further collaboration with NASA on a left ventricular assist device (LVAD). The High School for Health Sciences in Houston is named for DeBakey. DeBakey is consulted in the heart surgery case of Russian President Boris Yeltsin. Baylor and Methodist Hospital celebrate DeBakey’s 50th anniversary in Houston, but then split. Hurricane Katrina disrupts Tulane Medical School, and DeBakey is instrumental in a temporary transfer of personnel and students to Baylor. DeBakey suffers aortic dissection at age 97, but survives the operation—a procedure which he had helped to develop. He continues in his role as medical statesman. DeBakey receives the Congressional Gold Medal, and there is rapprochement between DeBakey and Cooley. Dr. DeBakey dies in 2008, mourned across the globe and recognized as one of the all-time greatest physician-scientists in history.

Ultrastructural observations of the aorta of calves implanted with a mechanical left ventricular assist device

1990 ◽  
Vol 48 (3) ◽  
pp. 834-835
Author(s):  
J P Cassella ◽  
V Salih ◽  
T R Graham
Keyword(s):  
Left Ventricular Assist Device ◽  
Ventricular Assist Device ◽  
Left Ventricular ◽  
Aortic Tissue ◽  
Assist Device ◽  
Ventricular Assist ◽  
Transmission Electron ◽  
Left Ventricular Assist ◽  
Preliminary Study

Left ventricular assist systems are being developed for eventual long term or permanent implantation as an alternative to heart transplantation in patients unsuitable for or denied the transplant option. Evaluation of the effects of these devices upon normal physiology is required. A preliminary study was conducted to evaluate the morphology of aortic tissue from calves implanted with a pneumatic Left Ventricular Assist device-LVAD. Two 3 month old heifer calves (calf 1 and calf 2) were electively explanted after 128 days and 47 days respectively. Descending thoracic aortic tissue from both animals was removed immediately post mortem and placed into karnovsky’s fixative. The tissue was subsequently processed for transmission electron microscopy (TEM). Some aortic tissue was fixed in neutral buffered formalin and processed for routine light microscopy.

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