Hemophilia

Author(s):  
Rebecca McIntyre

Patients with hemophilia can be safely managed for elective surgery such as adenotonsillectomy as long as adequate planning and consultation with the hematology department occurs. Adequate factor replacement, antifibrinolytics, and careful monitoring are the mainstays of care. The need for frequent venous access can make cannulation of veins difficult, and this can be stressful for the patient and his or her family. Careful planning of any cannulation attempts can alleviate stress, increase success rate, and reduce trauma to veins. If the patient has a long-term central venous line, all precautions to reduce the risk of infection and thrombosis in the line must be adhered to. Development of inhibitory antibodies to factor VIII, or more rarely to factor IX, is currently the most difficult complication to manage in hemophilia patients.

1998 ◽  
Vol 2 (1) ◽  
pp. 38-40
Author(s):  
Franco Tesio ◽  
Hamurabi De Baz ◽  
Giacomo Panarello

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Yuuki Iida ◽  
Kumiko Hongo ◽  
Takanobu Onoda ◽  
Yusuke Kita ◽  
Yukio Ishihara ◽  
...  

AbstractCentral venous port (CVP) is a widely used totally implantable venous access device. Recognition of risks associated with CVP-related complications is clinically important for safe, reliable, and long-term intravenous access. We therefore investigated factors associated with CVP infection and evulsion, including the device type. A total of 308 consecutive patients with initial CVP implantation between January 2011 and December 2017 were retrospectively reviewed, and the association of clinical features with CVP-related complications were analyzed. Intraoperative and postoperative complications occurred in 11 (3.6%) and 39 (12.7%) patients, respectively. The overall rate of CVP availability at six months was 91.4%. Malignancy and 2-Methacryloyloxyethyl phosphorylcholine (MPC) polymer-coated catheter use were negatively associated with the incidence of CVP infections. Accordingly, malignancy and MPC polymer-coated catheter use were independent predictors for lower CVP evulsion rate (odds ratio, 0.23 and 0.18, respectively). Furthermore, both factors were significantly associated with longer CVP availability (hazard ratio, 0.24 and 0.27, respectively). This retrospective study identified factors associated with CVP-related complications and long-term CVP availability. Notably, MPC polymer-coated catheter use was significantly associated with a lower rate of CVP infection and longer CVP availability, suggesting the preventive effect of MPC coating on CVP infection.


1991 ◽  
Vol 77 (2) ◽  
pp. 75-77
Author(s):  
R. A. Wheeler ◽  
T. J. W. Spalding ◽  
J. A. Thomas ◽  
G. A. Carss

AbstractCentral venous catheters (CVCs) are prone to accidental removal during patient transportation. Of the casualties who require transfer between medical facilities, those with CVC in situ require additional vigilance to prevent loss of the CVC, which continues to occur despite various methods of fixation. The fashioning of a subcutaneous tunnel has become an integral part of the placement of central venous catheters. Several methods have been described, but the long-term CVCs in paediatric practice pose special problems, particularly that of the patients continually testing the CVCs fixation. Using a new polyurethane CVC, a retrograde tunnelling technique has been developed which affords immediate and secure fixation. We propose that this CVC, together with the technique of retrograde tunnelling, is the solution to inadvertent central venous line removal during patient transfer.


1998 ◽  
Vol 2 (1) ◽  
pp. 38-40 ◽  
Author(s):  
Franco Tesio ◽  
Hamurabi De Baz ◽  
Giacomo Panarello

2014 ◽  
Vol 142 (3-4) ◽  
pp. 261-266
Author(s):  
Biljana Draskovic ◽  
Izabella Fabri ◽  
Anna Uram-Benka ◽  
Goran Rakic

Central venous catheters are of an essential importance to critically ill patients who require long-term venous access for various purposes. Their use made the treatment much easier, but still they are not harmless and are prone to numerous complications. Catheter infections represent the most significant complication in their use. The frequency of infections varies in different patient care settings, but their appearance mostly depends on the patient?s health condition, catheter insertion time, localization of the catheter and type of the used catheter. Since they are one of the leading causes of nosocomial infections and related to significant number of morbidity and mortality in intensive care units, it is very important that maximal aseptic precautions are taken during the insertion and the maintenance period. Prevention of infection of the central venous catheters demands several measures that should be applied routinely.


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