Spinal Cord Tumors

Mapping Intimacies ◽

10.1093/med/9780197512166.003.0105 ◽

2021 ◽

pp. 949-955

Author(s):

I. Darin Carabenciov ◽

Joon H. Uhm

Keyword(s):

Spinal Cord ◽

Clinical Characteristics ◽

Cauda Equina ◽

Spinal Tumors ◽

Tumor Type ◽

Spinal Cord Tumors ◽

Imaging Characteristics ◽

Anatomical Compartment ◽

Intradural Extramedullary

Spinal tumors can be broadly classified on the basis of the anatomical compartment they occupy. These tumors can be intramedullary, intradural extramedullary, or extradural. Regardless of location, significant neurologic morbidity can occur as a result of their effects on the spinal cord or the cauda equina, or both. This chapter summarizes the pathophysiologic factors, clinical characteristics, imaging characteristics, and treatment of each tumor type.

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Surgical outcome of intradural extramedullary spinal cord tumors - Our experience at a tertiary health care center

Grande Medical Journal ◽

10.3126/gmj.v1i2.27091 ◽

2020 ◽

Vol 1 (2) ◽

pp. 103-109

Author(s):

Gyanendra Joshi ◽

Binod Bijukachhe ◽

Javed Ahmad Khan

Keyword(s):

Spinal Cord ◽

Cauda Equina ◽

Clinical Results ◽

Spinal Tumors ◽

Myxopapillary Ependymoma ◽

Spinal Cord Tumors ◽

Vas Score ◽

Post Surgery ◽

Intradural Extramedullary

Introduction: To report the treatment results of 19 patients who underwent excision of intradural extramedullary (IDEM) spinal tumors. Materials & Methods: This is a retrospective study. Patients’ records were retrieved from the electronic database of Grande International Hospital. There were 19 IDEM spinal tumors excised over a period of 6 years between January 2013 and August 2019 by a single surgeon. There were 11 (57.9%) males and 8 (42.1%) females with an average age of 48.37±21.87 years (range, 5-79 years). The mean postoperative follow-up period was 12.87±14.88 months (range, 15 days - 60 months). The histopathological findings, locations of the tumors, and clinical results were analyzed. Neurological findings were evaluated using ASIA grading system and pain was evaluated using VAS score. Results: Histopathologically the tumors were: 8 meningioma (42.1%), 4 schwannoma (21.1%), 4 neurofibroma (21.1%), 1 dermoid cyst (5.3%), 1 lipoma (5.3%), and 1 myxopapillary ependymoma (5.3%). Tumor locations were: dorsal in 10 (52.6%), lumbar in 5 (26.3%), lumbosacral in 2 (10.5%), dorsolumbar in 1 (5.3%), and cervical in 1 (5.3%) patient. Neurologic status of 7 patients was normal and 12 had neurologic involvement with 3 patients having Cauda Equina Syndrome (CES) preoperatively. At the final follow-up, 3-grade, 2-grade and 1-grade improvement in ASIA score was observed in 1, 6 and 1 cases, respectively. There was no change in the ASIA grade in 1 case. All 3 cases of CES achieved full neural recovery. Preoperative VAS score was 9.21±1.08 and improved significantly to 0.74±1.62 after surgery. Neurological improvement was seen in 91.67% with complete recovery in 75% of the cases and not a single case deteriorated neurologically post-surgery. Conclusion: Most intradural-extramedullary spinal cord tumors are mostly benign and good clinical results can be obtained when adequately treated with surgery.

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Spinal Cord Tumors—Our 5-Year Experience

Indian Journal of Neurosurgery ◽

10.1055/s-0041-1730129 ◽

2022 ◽

Author(s):

Manpreet S. Banga ◽

B.V. Sandeep ◽

Anantha Kishan ◽

Arjun H. Dev ◽

Rajesh B. Devabhakthuni

Keyword(s):

Spinal Cord ◽

Retrospective Study ◽

Spinal Tumor ◽

Spinal Tumors ◽

Spinal Cord Tumors ◽

Motor Weakness ◽

Nerve Sheath Tumors ◽

Intradural Extramedullary ◽

The Common

Abstract Purpose To study the demography, incidence, symptoms, histopathology, postoperative complications and recovery in operated patients of spinal tumor. Overview of Literature Primary spinal cord tumors (SCT) are an uncommon entity. According to their location, spinal tumors are conveniently classified as extradural (ED) and intradural (ID), although some can be both inside and outside the dura. ID tumors can be intradural extramedullary (IDEM) or intramedullary SCT (IMSCT). Methods This is a retrospective study of 122 patients with spinal tumors who were surgically treated at the department of neurosurgery from 2014 to 2019 over a period of 5 years. Study Design This is a retrospective study. Results Out of 122 patients, there were 19 patients with ED tumor, 73 had IDEM, and 30 had IMSCT. As many as 73 patients were males and the rest of the 49 patients were females. Mean age at time of surgery was 40.79 years. The thoracic region of spinal canal was most frequently involved (64; 52.4%). The common clinical symptom was motor weakness (90 cases; 73.77%). Majority of the patients had symptoms for duration of 6 to 12 months. Schwannomas were the most common tumor among IDEM and extradural location. Ependymomas were the most common type in IMSCT. We observed significant improvement in most of our cases. Four patients deteriorated at 3 months follow- up. Conclusions There was a higher male:female ratio for all spinal cord tumors except meningiomas. There was also a higher proportion of nerve sheath tumors, and a lower proportion of meningiomas and neuroepithelial tumors. These results are similar to other studies from Asian countries.

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Clinical outcome of intradural extramedullary spinal cord tumors: A single-center retrospective analytical study

Surgical Neurology International ◽

10.25259/sni_839_2020 ◽

2021 ◽

Vol 12 ◽

pp. 145

Author(s):

Pratik Patel ◽

Dhanish Mehendiratta ◽

Vivek Bhambhu ◽

Samir Dalvie

Keyword(s):

Spinal Cord ◽

Clinical Outcome ◽

Surgical Intervention ◽

Spinal Tumors ◽

Cerebrospinal Fluid Leakage ◽

Karnofsky Performance Score ◽

Spinal Cord Tumors ◽

Mri Scans ◽

Intradural Extramedullary ◽

Acute Neurological Deterioration

Background: Intradural extramedullary spinal cord tumors (IESCT) account for approximately two-thirds of largely benign intraspinal neoplasms. They occasionally present with acute neurological deterioration warranting emergent surgical intervention. Methods: Here, we reviewed a series of 31 patients with intradural extramedullary spinal tumors who underwent surgery from 2012 to 2019. Patients averaged 50.8 years of age, and there were 16 males and 15 females. Patients were followed for a minimum of 1 year. Multiple clinical outcome variables were studied (e.g., Karnofsky Performance Score [KPS], visual analog scale (VAS), and Frankel grade). Results: The majority of IESCT tumors were found in the thoracic spine 18 (58.06%) followed by the lumbar 8 (25.80%), cervical 1 (3.22%), and combined junctional tumors 4 (12.90%) (cervicothoracic-02 and thoracolumbar-02). Histopathological diagnoses included schwannomas-16 (51.61%), meningiomas-11 (35.48%), lipomas-2 (6.45%), hemangiomas-1 (3.22), and ependymomas-01 (03.22%). The VAS score was reduced in all cases, while KPS and Frankel grades were significantly improved. Complications included cerebrospinal fluid leakage, new/residual paresthesias, and tumor recurrence (12.50%). Conclusion: Most intradural extramedullary tumors are benign and are readily diagnosed utilizing MRI scans. Notably, good functional outcomes follow surgical intervention.

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Clinical profile, management and surgical outcome of spinal cord tumors

International Surgery Journal ◽

10.18203/2349-2902.isj20213986 ◽

2021 ◽

Vol 8 (10) ◽

pp. 3013

Author(s):

Shobhit Chhabra ◽

Bhagirath More ◽

Deepak Ranade ◽

Sarang Gotecha ◽

Prashant Punia ◽

...

Keyword(s):

Spinal Cord ◽

Surgical Excision ◽

Spinal Tumor ◽

Spinal Tumors ◽

Cervical Cord ◽

Subtotal Resection ◽

Histopathological Diagnosis ◽

Tumor Type ◽

Spinal Cord Tumors ◽

Significant Drop

Background: Spinal cord tumors can result in dramatic neurological and functional disabilities in the patients. We aimed to know the incidence of different types of spinal tumors and correlation between clinical presentation and pathological findings and compare outcomes of these tumors postoperatively.Methods: A total of 50 patients were included in the study group. After a thorough clinical evaluation, patients were subjected to a magnetic resonance imaging (MRI) and then surgery. They were described on the basis of age, sex, location of the tumor, type of the tumor, symptoms, histopathological type, surgical resection and complications.Results: Study included 29 males and 21 females and their age ranged from 5 years to 70 years. Out of the 50 patients, 39 had intradural and 11 had extradural spinal tumors. Amongst the 39 intradural tumors, 27 were extramedullary and 12 were intramedullary in location. A predilection towards the thoracic region (44%) was seen followed by the cervical cord. The tumors were excised completely in 68% of the patients while subtotal resection was done in 18% and near total resection in 14% patients. There was significant drop in VAS score and improvement in McCormicks score at 3 months of follow up.Conclusions: Based on this study it could be suggested that surgical excision and decompression should be attempted in all patients of intradural spinal tumor fit to undergo the procedure, as it not only helps in reaching a definitive histopathological diagnosis but also achieves neurological improvement in most patients without causing significant morbidity and mortality.

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Mr Imaging of Intradural Extramedullary Tumors

Acta Radiologica ◽

10.1177/028418519203300303 ◽

1992 ◽

Vol 33 (3) ◽

pp. 207-212 ◽

Cited By ~ 19

Author(s):

M. H. Li ◽

S. Holtås ◽

E.-M. Larsson

Keyword(s):

Spinal Cord ◽

Mr Imaging ◽

Subarachnoid Space ◽

Signal Intensity ◽

Cauda Equina ◽

Spinal Tumors ◽

Broad Base ◽

Epidural Fat ◽

Intradural Extramedullary ◽

T2 Weighted Images

Thirty-one consecutive intradural extramedullary spinal tumors examined with MR at 0.3 T were reviewed. In 13 of the patients myelography had been performed. There were 11 patients with meningeoma, 14 with neuroma, one ependymoma, 3 metastases, and 2 lipomas. All tumors were surgically removed and verified by histology. The intradural extramedullary location of the tumors was accurately assessed by MR imaging in all patients and by myelography in 10 of 13. The MR diagnoses were in accordance with the histologic findings in 74% of cases. Compression of the spinal cord or cauda equina with widening of the subarachnoid space above and below the mass or outward displacement of epidural fat was characteristic of the intradural extramedullary tumors. The signal intensity of meningeoma as well as of neuroma was slightly lower or equal to that of the cord on T1-weighted images, and equal to or higher than cord signal on T2-weighted images. Neuroma had a lower signal intensity on T1-weighted images and a higher signal intensity on T2-weighted images than meningeoma. Meningeoma appeared more homogeneous than neuroma and had a broad base towards the dura.

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