HIV-related malignancies

2019 ◽  
pp. 427-432
Keyword(s):  
Immune Deficiency ◽  
Hiv Infection ◽  
Immune Deficiency Syndrome ◽  
Deficiency Syndrome ◽  
Current Treatment ◽  
Nursing Management ◽  
Immunodeficiency Virus ◽  
History Of ◽  
Acquired Immune Deficiency

A brief overview of the history of the development of human immunodeficiency virus (HIV) infection in international populations is considered, before describing the current treatment with standard antiretroviral therapy (ART). The link between HIV infection and the development of cancers is discussed, along with the classification of tumours which define the development of acquired immune deficiency syndrome (AIDS) and those which do not define AIDS but remain more common in HIV-infected populations. The challenges of treating cancer in an immunosuppressed poulation are raised, and the importance of seeking expert opinion on this treatment is flagged. The chapter concludes with an overview of the nursing management of patients with both HIV infection and cancer, with particular regard to patient education, the adapting of standard oncological treatments to meet the needs of this population, and the management of patients who may be stigmatized by HIV infection.

HIV: A Chronic Condition

2015 ◽  
Vol 45 (3-4) ◽  
pp. 136-141
Author(s):  
Daniel D. Zimmerman
Keyword(s):  
Immune Deficiency ◽  
Chronic Disease ◽  
Hiv Infection ◽  
Immune Deficiency Syndrome ◽  
Acquired Immune Deficiency Syndrome ◽  
Deficiency Syndrome ◽  
Immunodeficiency Virus ◽  
Life Threatening ◽  
Acquired Immune Deficiency ◽  
Chronic Hiv Infection

By virtue of the success of anti-retroviral therapy (ART), human immunodeficiency virus (HIV) infection has evolved into a chronic disease in which the typical complications of acquired immune deficiency syndrome (AIDS) are no longer the dominant problem. Rather than dealing with acute and potentially life-threatening complications, clinicians are now confronted with managing a chronic disease that, in the absence of a cure, will persist for many decades.1 This review will focus on the longer term sequelae and consequences of chronic HIV infection.

scholarly journals Thrombotic Thrombocytopenic Purpura Associated with the Acquired Immune Deficiency Syndrome

1992 ◽  
Vol 3 (1) ◽  
pp. 37-41
Author(s):  
Anand Kumar ◽  
Jean Wang ◽  
David Sutton ◽  
Eric J Bow
Keyword(s):  
Immune Deficiency ◽  
Hiv Infection ◽  
Thrombotic Thrombocytopenic Purpura ◽  
Immune Deficiency Syndrome ◽  
Acquired Immune Deficiency Syndrome ◽  
Deficiency Syndrome ◽  
Laboratory Findings ◽  
Thrombocytopenic Purpura ◽  
Immunodeficiency Virus ◽  
Acquired Immune Deficiency

A bisexual male presented with acute thrombotic thrombocytopenic purpura (TTP) in association with established acquired immune deficiency syndrome. The patient had classic clinical and laboratory findings of TTP and responded well to plasmapheresis therapy. Previously reported cases of TTP in association with human immunodeficiency virus (HIV) infection are briefly reviewed. Basic concepts in the pathogenesis of TTP are examined in reference to HIV infection.

Estimation of the incidence of HIV infection

1989 ◽  
Vol 325 (1226) ◽  
pp. 113-121 ◽  
Keyword(s):  
Immune Deficiency ◽  
Human Immunodeficiency Virus ◽  
Hiv Infection ◽  
Immune Deficiency Syndrome ◽  
Acquired Immune Deficiency Syndrome ◽  
Deficiency Syndrome ◽  
Back Projection ◽  
The United Kingdom ◽  
Immunodeficiency Virus ◽  
Acquired Immune Deficiency

The aim of the method of ‘back projection’ is to provide estimates of the number of new infections with the human immunodeficiency virus (HIV) as a function of time, by using the numbers of diagnoses of the acquired immune deficiency syndrome (AIDS) together with information on the distribution of the incubation period between infection and diagnosis. Here, the method is investigated with particular reference to cases of HIV infection and AIDS in the United Kingdom.

scholarly journals The origin of acquired immune deficiency syndrome: Darwinian or Lamarckian?

2001 ◽  
Vol 356 (1410) ◽  
pp. 877-887 ◽  
Author(s):  
Tom Burr ◽  
J. M. Hyman ◽  
Gerald Myers
Keyword(s):  
Immune Deficiency ◽  
Simulated Data ◽  
Immune Deficiency Syndrome ◽  
Acquired Immune Deficiency Syndrome ◽  
Deficiency Syndrome ◽  
Darwinian Evolution ◽  
Immunodeficiency Virus ◽  
Acquired Immune Deficiency ◽  
Hiv 1

The subtypes of human immunodeficiency virus type 1 (HIV–1) group M exhibit a remarkable similarity in their between–subtype distances, which we refer to as high synchrony. The shape of the phylogenetic tree of these subtypes is referred to as a sunburst to distinguish it from a simple star phylogeny. Neither a sunburst pattern nor a comparable degree of symmetry is seen in a natural process such as in feline immunodeficiency virus evolution. We therefore have undertaken forward–process simulation studies employing coalescent theory to investigate whether such highly synchronized subtypes could be readily produced by natural Darwinian evolution. The forward model includes both classical (macro) and molecular (micro) epidemiological components. HIV–1 group M subtype synchrony is quantified using the standard deviation of the between–subtype distances and the average of the within–subtype distances. Highly synchronized subtypes and a sunburst phylogeny are not observed in our simulated data, leading to the conclusion that a quasi–Lamarckian, punctuated event occurred. The natural transfer theory for the origin of human acquired immune deficiency syndrome (AIDS) cannot easily be reconciled with these findings and it is as if a recent non–Darwinian process took place coincident with the rise of AIDS in Africa.

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