Haematological disorders

2011 ◽  
Author(s):  
Carl Waldmann ◽  
Neil Soni ◽  
Andrew Rhodes
Keyword(s):  
Critical Care ◽  
Sickle Cell ◽  
Disseminated Intravascular Coagulation ◽  
Sickle Cell Anaemia ◽  
Bleeding Disorders ◽  
Haematological Malignancies ◽  
Intravascular Coagulation ◽  
Neutropenic Sepsis ◽  
Haematological Disorders ◽  
Digital Ischaemia

Bleeding disorders 388Anaemia in critical care 392Sickle cell anaemia 394Haemolysis 396Disseminated intravascular coagulation 398Neutropenic sepsis 400Haematological malignancies in the ICU 404Coagulation monitoring 406Inappropriate activation of the coagulation process. Usually presents as haemorrhage, but 5-10% may show micro-thrombi (e.g. digital ischaemia)....

Haematological disorders

2019 ◽  
pp. 431-449
Author(s):  
Carl Waldmann ◽  
Andrew Rhodes ◽  
Neil Soni ◽  
Jonathan Handy
Keyword(s):  
Critical Care ◽  
Sickle Cell ◽  
Sickle Cell Anaemia ◽  
Viral Infections ◽  
Fungal Infections ◽  
Haematopoietic Stem Cell ◽  
Cell Transplant ◽  
Bleeding Disorders ◽  
Neutropenic Sepsis ◽  
Haematological Disorders

This chapter discusses haematological disorders and includes discussion on bleeding disorders (including acquired bleeding disorders and inherited bleeding disorders), anaemia in critical care (including discussion on pathogenesis, consequences of anaemia, approach to the investigation of anaemia, classification of anaemia, measures to minimize blood loss in the intensive care unit [ICU], and erythropoietin). It also covers sickle cell anaemia (transfusion in sickle cell anaemia, including hyperhaemolysis, acute chest syndrome, and pulmonary hypertension in sickle cell disease), haemolysis (haemolytic conditions particularly relevant to critical care), disseminated intravascular coagulation, neutropenic sepsis (including persistent fever or inadequate clinical response, fungal infections, empirical antifungal therapy, viral infections, granulocyte-colony stimulating factor, and granulocytes for neutropenia). Finally, the chapter discusses haematological malignancies in the ICU (neutropenia and neutropenic sepsis, tumour lysis syndrome, hyperviscosity syndromes, hyperleukocytosis, haemorrhagic complications, haematopoietic stem cell transplant, graft versus host disease, and corticosteroids) and coagulation monitoring.

Disseminated Intravascular Coagulation in Sickle Cell Crisis

1979 ◽  
Vol 72 (4) ◽  
pp. 505-506 ◽  
Author(s):  
ANTHONY I. CORVELLI ◽  
RICHARD A. BINDER ◽  
ARTHUR KALES
Keyword(s):  
Sickle Cell ◽  
Disseminated Intravascular Coagulation ◽  
Intravascular Coagulation ◽  
Sickle Cell Crisis

Presepsin (sCD14-ST) as a biomarker of sepsis in clinical practice and in emergency department: a mini review

2015 ◽  
Vol 39 (6) ◽  
Author(s):  
Ali Kemal Erenler ◽  
Turker Yardan
Keyword(s):  
Emergency Department ◽  
Critical Care ◽  
Intensive Care ◽  
Clinical Practice ◽  
Intensive Care Units ◽  
Disseminated Intravascular Coagulation ◽  
Kidney Failure ◽  
Protein Complexes ◽  
Intravascular Coagulation ◽  
Lps Binding

AbstractPresepsin is a 13-kDa protein that is a fragment of CD14 with truncated N-terminal, the receptor for lipopolysaccharide (LPS)/LPS-binding protein complexes. It is a novel marker being sought in many diseases such as sepsis, kidney failure, disseminated intravascular coagulation, etc. In this review, we aimed to clarify its utility in critical diseases and availability in critical care settings such as emergency departments and intensive care units.

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