Disorders of the kidney and upper urinary tract in children
The majority of clinically significant congenital disorders of the upper urinary tract are now detected prenatally. Commonly identified abnormalities include pelviureteric junction obstruction (PUJO), vesicoureteric junction obstruction (VUJO), duplication anomalies, multicystic dysplastic kidney (MCDK), high grade vesicoureteric reflux (VUR) and anomalies of renal migration and/or fusion. Most affected infants are asymptomatic at birth and further investigation can usually be undertaken on a non-urgent basis in the first few weeks or months of life. Long-term natural history studies have shown that many of these conditions can be managed non-operatively. In most cases, standardized procedures such as pyeloplasty and ureteric reimplantation give predictably satisfactory results. Long-term outcome data for surgical and conservative management of upper tract disorders in children is sparse and research in this area is still required.