Disorders of the kidney and upper urinary tract in children

Author(s):  
Kim Hutton

The majority of clinically significant congenital disorders of the upper urinary tract are now detected prenatally. Commonly identified abnormalities include pelviureteric junction obstruction (PUJO), vesicoureteric junction obstruction (VUJO), duplication anomalies, multicystic dysplastic kidney (MCDK), high grade vesicoureteric reflux (VUR) and anomalies of renal migration and/or fusion. Most affected infants are asymptomatic at birth and further investigation can usually be undertaken on a non-urgent basis in the first few weeks or months of life. Long-term natural history studies have shown that many of these conditions can be managed non-operatively. In most cases, standardized procedures such as pyeloplasty and ureteric reimplantation give predictably satisfactory results. Long-term outcome data for surgical and conservative management of upper tract disorders in children is sparse and research in this area is still required.

2001 ◽  
Vol 8 (1) ◽  
pp. 6-9 ◽  
Author(s):  
Shigeru Minowada ◽  
Yukio Homma ◽  
Takumi Takeuchi ◽  
Toshiyuki Kamijo ◽  
Tadaichi Kitamura

2009 ◽  
Vol 23 (1) ◽  
pp. 75-80 ◽  
Author(s):  
Shiu-Dong Chung ◽  
Shyh-Chyan Chen ◽  
Shuo-Meng Wang ◽  
Shih-Chieh Chueh ◽  
Ming-Kuen Lai ◽  
...  

2013 ◽  
Vol 31 (6_suppl) ◽  
pp. 265-265
Author(s):  
Takahiro Yoneyama ◽  
Naoki Sugiyama ◽  
Yuuichirou Suzuki ◽  
Akiko Okamoto ◽  
Hayato Yamamoto ◽  
...  

265 Background: Bacillus Calmette-Guerin (BCG) therapy has already been established as a treatment for muscle noninvasive bladder cancer. Although there are several reports indicating the effectiveness of BCG perfusion therapy for the upper urinary tract urothelial carcinoma in situ (CIS), it is not well established yet. We conducted a retrospective study to assess the long-term outcome of BCG perfusion therapy for the upper urinary tract CIS. Methods: Twenty-six subjects (20 male, 6 female) who received BCG perfusion therapy for the upper urinary tract CIS from December 1997 to December 2011 were enrolled. Ten subjects had the entire urinary tract CIS, seven had bilateral, nine had unilateral CIS of the urinary tract. The average period of observation was 52.6 months (ranging from 5 to 156 months), and the average subject age was 73.6 years (ranging from 56 to 90 years). We used a double-J catheter for 17 cases, a transvesical single-J catheter whose curl was positions in an upper calyx for eight cases, and a straight ureteral catheter inserted for ureterocutaneostomy for one case. We used 80 mg of BCG for the first five cases, 40 mg for the late twenty-one cases. Urine cytology was performed to assess the treatment validity. Results: Of the 26 cases, the treatment protocol was completed in 21 cases. Urine cytology tests became negative in 22 of the 26 subjects (84.6%) who underwent upper urinary tract perfusion. Among these 22 subjects who had negative tests, five subjects had a recurrence in their upper urinary tracts. Side effects were observed in 25 subjects (96.5%), and the most common side effect was bladder irritation. Localized renal tuberculosis which was successfully treated with conservative therapy was seen in two cases. Conclusions: BCG perfusion therapy for the upper urinary tract CIS is active. However, severe side effects are possible, and careful observation is essential while using this therapy.


2000 ◽  
Vol 163 (4) ◽  
pp. 1105-1107 ◽  
Author(s):  
MICHEL E. JABBOUR ◽  
FRANÇOIS DESGRANDCHAMPS ◽  
SEBASTIEN CAZIN ◽  
PIERRE TEILLAC ◽  
ALAIN LE DUC ◽  
...  

2020 ◽  
Vol 128 (10) ◽  
pp. 687-692 ◽  
Author(s):  
Joachim Feldkamp ◽  
F. Grünwald ◽  
Markus Luster ◽  
Kerstin Lorenz ◽  
Christian Vorländer ◽  
...  

AbstractThyroid nodules and cysts are frequently diagnosed in Germany with a prevalence of about 20% in young adults reaching up to 70% in older adults. Surgery is the standard treatment of symptomatic nodules, nodules with suspicion of malignancy and thyroid cancer. Radioiodine treatment is applied for autonomously functioning nodules. During the last years new non-surgical and non-radioiodine techniques have been introduced to treat thyroid nodules. These techniques include ethanol/polidocanol treatment, radiofrequency, microwave, and laser ablation, and high frequency ultrasound ablation. A significant reduction in nodule size could be documented for these techniques in several studies, but long-term outcome data are missing. Until now, there is no general consensus regarding the appropriate indications for these methods. For this reason, the Thyroid Section (German Society for Endocrinology), the Thyroid Working Committee (German Society for Nuclear Medicine), and the German Association of Endocrine Surgeons (CAEK) for the German Society of General and Visceral Surgery (DGAV) reviewed the respective literature, discussed the pro and cons and developed a consensus statement and recommendation to help physicians and patients in their decision making.


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