DIPG-22. A PHASE 1 TRIAL OF THE HISTONE DEACETYLASE INHIBITOR PANOBINOSTAT IN PEDIATRIC PATIENTS WITH RECURRENT OR REFRACTORY DIFFUSE INTRINSIC PONTINE GLIOMA: A PEDIATRIC BRAIN TUMOR CONSORTIUM (PBTC) STUDY

Pontine Glioma ◽

Deacetylase Inhibitor ◽

Quantifying radiation therapy response using apparent diffusion coefficient (ADC) parametric mapping of pediatric diffuse intrinsic pontine glioma: a report from the pediatric brain tumor consortium

Journal of Neuro-Oncology ◽

10.1007/s11060-019-03133-y ◽

2019 ◽

Vol 143 (1) ◽

pp. 79-86 ◽

Cited By ~ 4

Author(s):

Rafael Ceschin ◽

Mehmet Kocak ◽

Sridhar Vajapeyam ◽

Ian F. Pollack ◽

Arzu Onar-Thomas ◽

...

Keyword(s):

Diffusion Coefficient ◽

Radiation Therapy ◽

Brain Tumor ◽

Therapy Response ◽

Pediatric Brain Tumor ◽

Pontine Glioma ◽

Parametric Mapping ◽

Apparent Diffusion ◽

Abstract 5416: Positioning the NQO1-bioactivatable drug isobutyl-deoxynyboquinone in diffuse intrinsic pontine glioma (DIPG): an exceptional therapeutic opportunity in pediatric brain tumor

10.1158/1538-7445.am2020-5416 ◽

2020 ◽

Author(s):

Maxime Henri Janin ◽

Vanessa Ortiz Barahona ◽

Pere Llinas Arias ◽

Carolina De La Torre ◽

Angel Montero Carcaboso ◽

...

Keyword(s):

Brain Tumor ◽

Pediatric Brain Tumor ◽

Pontine Glioma ◽

Therapeutic Opportunity ◽

Advanced ADC Histogram, Perfusion, and Permeability Metrics Show an Association with Survival and Pseudoprogression in Newly Diagnosed Diffuse Intrinsic Pontine Glioma: A Report from the Pediatric Brain Tumor Consortium

American Journal of Neuroradiology ◽

10.3174/ajnr.a6499 ◽

2020 ◽

Vol 41 (4) ◽

pp. 718-724

Author(s):

S. Vajapeyam ◽

D. Brown ◽

C. Billups ◽

Z. Patay ◽

G. Vezina ◽

...

Keyword(s):

Brain Tumor ◽

Pediatric Brain Tumor ◽

Newly Diagnosed ◽

Pontine Glioma ◽

ADVL1513: Results of a phase 1 trial of entinostat, an oral histone deacetylase inhibitor, in pediatric patients with recurrent or refractory solid tumors.

Journal of Clinical Oncology ◽

10.1200/jco.2018.36.15_suppl.10556 ◽

2018 ◽

Vol 36 (15_suppl) ◽

pp. 10556-10556 ◽

Cited By ~ 3

Author(s):

Suman Malempati ◽

Bill H. Chang ◽

Joel M. Reid ◽

Xiaowei Liu ◽

Charles G. Minard ◽

...

Keyword(s):

Solid Tumors ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Pediatric Patients ◽

Phase 1 ◽

Phase 1 Trial ◽

Deacetylase Inhibitor

Apparent diffusion coefficient histogram metrics correlate with survival in diffuse intrinsic pontine glioma: a report from the Pediatric Brain Tumor Consortium

Neuro-Oncology ◽

10.1093/neuonc/nov256 ◽

2015 ◽

Vol 18 (5) ◽

pp. 725-734 ◽

Cited By ~ 28

Author(s):

Tina Young Poussaint ◽

Sridhar Vajapeyam ◽

Kelsey I. Ricci ◽

Ashok Panigrahy ◽

Mehmet Kocak ◽

...

Keyword(s):

Diffusion Coefficient ◽

Brain Tumor ◽

Apparent Diffusion Coefficient ◽

Pediatric Brain Tumor ◽

Pontine Glioma ◽

Apparent Diffusion ◽

Correlation of 18 F-FDG PET and MRI Apparent Diffusion Coefficient Histogram Metrics with Survival in Diffuse Intrinsic Pontine Glioma: A Report from the Pediatric Brain Tumor Consortium

Journal of Nuclear Medicine ◽

10.2967/jnumed.116.185389 ◽

2017 ◽

Vol 58 (8) ◽

pp. 1264-1269 ◽

Cited By ~ 14

Author(s):

Katherine A. Zukotynski ◽

Sridhar Vajapeyam ◽

Frederic H. Fahey ◽

Mehmet Kocak ◽

Douglas Brown ◽

...

Keyword(s):

Diffusion Coefficient ◽

Brain Tumor ◽

Apparent Diffusion Coefficient ◽

Fdg Pet ◽

Pediatric Brain Tumor ◽

Pontine Glioma ◽

Apparent Diffusion ◽

ET-06 * PRECLINICAL TESTING OF THE HISTONE DEACETYLASE INHIBITOR, PANOBINOSTAT, IN A GENETICALLY ENGINEERED DIFFUSE INTRINSIC PONTINE GLIOMA MOUSE MODEL

Neuro-Oncology ◽

10.1093/neuonc/nou255.6 ◽

2014 ◽

Vol 16 (suppl 5) ◽

pp. v80-v80

Author(s):

K. Barton ◽

K. Misuraca ◽

O. Becher

Keyword(s):

Mouse Model ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Genetically Engineered ◽

Pontine Glioma ◽

Preclinical Testing ◽

Deacetylase Inhibitor

A phase I/II clinical trial of veliparib (ABT-888) and radiation followed by maintenance therapy with veliparib and temozolomide in patients with newly diagnosed diffuse intrinsic pontine glioma (DIPG): A Pediatric Brain Tumor Consortium Interim Report of Phase I Study.

Journal of Clinical Oncology ◽

10.1200/jco.2015.33.15_suppl.10053 ◽

2015 ◽

Vol 33 (15_suppl) ◽

pp. 10053-10053

Author(s):

Patricia Ann Baxter ◽

Jack M. Su ◽

Xiao-Nan Li ◽

Arzu Onar-Thomas ◽

Catherine A Billups ◽

...

Keyword(s):

Clinical Trial ◽

Brain Tumor ◽

Phase I ◽

Phase I Study ◽

Pediatric Brain Tumor ◽

Newly Diagnosed ◽

Interim Report ◽

Pontine Glioma ◽

A phase 1 and pharmacokinetic study of enzastaurin in pediatric patients with refractory primary central nervous system tumors: a pediatric brain tumor consortium study

Neuro-Oncology ◽

10.1093/neuonc/nou114 ◽

2014 ◽

Vol 17 (2) ◽

pp. 303-311 ◽

Cited By ~ 8

Author(s):

L. B. Kilburn ◽

M. Kocak ◽

R. L. Decker ◽

C. Wetmore ◽

M. Chintagumpala ◽

...

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Brain Tumor ◽

Pharmacokinetic Study ◽

Pediatric Patients ◽

Phase 1 ◽

Pediatric Brain Tumor ◽

Central Nervous System Tumors ◽

Nervous System Tumors ◽

EPT-15A PHASE1/2 CLINICAL TRIAL OF VELIPARIB (ABT-888) AND RADIATION FOLLOWED BY MAINTENANCE THERAPY WITH VELIPARIB AND TEMOZOLOMIDE (TMZ) IN PATIENTS WITH NEWLY DIAGNOSED DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG): A PEDIATRIC BRAIN TUMOR CONSORTIUM INTERIM REPORT OF PHASE II STUDY

Neuro-Oncology ◽

10.1093/neuonc/now069.14 ◽

2016 ◽

Vol 18 (suppl 3) ◽

pp. iii27.1-iii27 ◽

Cited By ~ 3

Author(s):

Patricia Baxter ◽

Jack Su ◽

Xiao-nan Li ◽

Arzu Onar Thomas ◽

Catherine Billups ◽

...

Keyword(s):

Clinical Trial ◽

Brain Tumor ◽

Maintenance Therapy ◽

Phase Ii Study ◽

Pediatric Brain Tumor ◽

Newly Diagnosed ◽

Interim Report ◽

Pontine Glioma ◽