Inbreeding and Population Structure
2020 ◽
pp. 47-74
Keyword(s):
Inbreeding and its consequences are the main subject of Chapter 3, beginning with the concepts of identity by descent versus identity by state, the inbreeding coefficient F, genotype frequencies with inbreeding, and calculation of the inbreeding coefficient from pedigrees. Inbreeding and heterosis are discussed along with the effects of inbreeding in humans and other organisms, regular systems of mating (selfing and partial selfing, sib mating), and the utility of recombinant inbred lines. The chapter emphasizes the intimate connection between inbreeding and hierarchical population structure as measured by the F-statistics.
2018 ◽
Vol 2018
(2)
◽
pp. 100-108
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Keyword(s):
1993 ◽
Vol 33
(6)
◽
pp. 1223-1228
◽
Keyword(s):
Keyword(s):
1990 ◽
Vol 79
(3)
◽
pp. 321-330
◽
Keyword(s):