scholarly journals Vasoactive mediators and renal haemodynamics in exertional heat stroke complicated by acute renal failure

QJM ◽  
2003 ◽  
Vol 96 (3) ◽  
pp. 193-201 ◽  
Author(s):  
Y.-F. Lin

1988 ◽  
Vol 11 (2) ◽  
pp. 184-187 ◽  
Author(s):  
M.E. Pattison ◽  
J.L. Logan ◽  
S.M. Lee ◽  
D.A. Ogden


1992 ◽  
Vol 12 (4) ◽  
pp. 252-258 ◽  
Author(s):  
Shang-Der Shieh ◽  
Yuh-Feng Lin ◽  
Kuo-Cheng Lu ◽  
Bi-Lian Li ◽  
Pauling Chu ◽  
...  


1997 ◽  
Vol 12 (10) ◽  
pp. 2087-2092 ◽  
Author(s):  
F. Yu ◽  
K. Lu ◽  
S. Lin ◽  
G. Chen ◽  
P. Chu ◽  
...  


Nephron ◽  
1995 ◽  
Vol 71 (4) ◽  
pp. 428-432 ◽  
Author(s):  
Shang-Der Shieh ◽  
Yuh-Feng Lin ◽  
Shih-Hua Lin ◽  
Kuo-Cheng Lu


2005 ◽  
Vol 72 (4) ◽  
pp. 446-456
Author(s):  
C. Alberti ◽  
M. Piovano ◽  
A. Tizzani

Contrast media-induced nephropathy (CN) is an important cause of hospital-acquired acute renal failure. Patients with both diabetes mellitus and renal impairment are at high risk. CN pathophysiology involves activation of the tubulo-glomerular feedback and vasoactive mediators such as renin-angiotensin 2, endothelin, adenosine, ADH, etc. The risk of CN can be minimized by the use of non-ionic, low or isoosmolar, contrast material, adequate hydration and prophylactic pharmacological measures. In patients with chronic renal failure who are undergoing arteriography (e.g. coronary angiography and angioplasty), periprocedural hemofiltration appears effective in preventing further renal damage due to contrast agents.



2011 ◽  
Vol 1 (2) ◽  
pp. 33-35
Author(s):  
Rana A. Nabalawi

Background: Heat induced illnesses are variable from a mild heat exhaustion to a severe heat stroke and its systemic complications. Millions of pilgrims annually perform the Islamic obligatory mission of Hajj, are vulnerable to heat induced illnesses, especially when Hajj falls in the summer period. This is a retrospective study of the renal and electrolyte abnormalities in heat stroke patients during Hajj. Method: We selected randomly 472 patients out of 2044 patients diagnosed as heat stroke over 5 years from 1986-1991 for this study. The diagnosis of heat stroke was based on: 1) Rectal temperature > 40°C, 2) Hot dry skin and 3) Neurological deficit presenting as delirium, coma with or without convulsions. The renal function and electrolytes of all these patients were obtained. Results: All the 472 patients revealed significant electrolyte abnormalities: hypophasphatemia 98% (P + 0.55 ± 0.05 mmol/L), hyponatremia Na+ 70% (128 + 1 mmol/L), hypocalcemia 70% (Ca + 2.01 ± 0.02 mmol/L), hypokalemia 32% (K+3.3 ± 01 mmol/L), and hypomagnesaemia (Mg 0.06 ± 0.01 mmol/L) in 30%. Metabolic acidosis and compensatory respiratory alkalosis was seen in most patients. Acute renal failure that required dialysis developed in 180 (8.8%) patients. In 100 patients, the most common cause was Rhabdomyolysis (68%). The rest had ischemic acute tubular necrosis (32%) with a mortality of 15% compared to 20% in all the 472 patients. The risk mortality was higher in patients with a temperature of 42°C, comatose at presentation and older than 50 years. Conclusion: During Hajj, electrolyte abnormalities in heat stroke were found to be fairly common. Acute renal failure was mainly due to Rhabdomyolysis, which carry better prognosis compared to other causes of acute tubular necrosis.



1973 ◽  
Vol 66 (3) ◽  
pp. 330-333 ◽  
Author(s):  
SYBIL F. RAJU ◽  
GUY H. ROBINSON ◽  
JOHN D. BOWER


2011 ◽  
Vol 1 (2) ◽  
pp. 33-35
Author(s):  
Rana A. Nabalawi

Background: Heat induced illnesses are variable from a mild heat exhaustion to a severe heat stroke and its systemic complications. Millions of pilgrims annually perform the Islamic obligatory mission of Hajj, are vulnerable to heat induced illnesses, especially when Hajj falls in the summer period. This is a retrospective study of the renal and electrolyte abnormalities in heat stroke patients during Hajj. Method: We selected randomly 472 patients out of 2044 patients diagnosed as heat stroke over 5 years from 1986-1991 for this study. The diagnosis of heat stroke was based on: 1) Rectal temperature > 40°C, 2) Hot dry skin and 3) Neurological deficit presenting as delirium, coma with or without convulsions. The renal function and electrolytes of all these patients were obtained. Results: All the 472 patients revealed significant electrolyte abnormalities: hypophasphatemia 98% (P + 0.55 ± 0.05 mmol/L), hyponatremia Na+ 70% (128 + 1 mmol/L), hypocalcemia 70% (Ca + 2.01 ± 0.02 mmol/L), hypokalemia 32% (K+3.3 ± 01 mmol/L), and hypomagnesaemia (Mg 0.06 ± 0.01 mmol/L) in 30%. Metabolic acidosis and compensatory respiratory alkalosis was seen in most patients. Acute renal failure that required dialysis developed in 180 (8.8%) patients. In 100 patients, the most common cause was Rhabdomyolysis (68%). The rest had ischemic acute tubular necrosis (32%) with a mortality of 15% compared to 20% in all the 472 patients. The risk mortality was higher in patients with a temperature of 42°C, comatose at presentation and older than 50 years. Conclusion: During Hajj, electrolyte abnormalities in heat stroke were found to be fairly common. Acute renal failure was mainly due to Rhabdomyolysis, which carry better prognosis compared to other causes of acute tubular necrosis.



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