CORRELATION OF EYE LENS DOSES AND PERSONAL DOSE EQUIVALENT MEASURED ON THE ARM OF INTERVENTIONAL CARDIOLOGISTS FOR A RETROSPECTIVE ASSESSMENT OF DOSES TO OPERATORS’ EYE LENS

2020 ◽  
Vol 189 (3) ◽  
pp. 271-278
Author(s):  
Joanna Domienik-Andrzejewska ◽  
Marcin Brodecki ◽  
Marek Zmyślony
Keyword(s):  
Threshold Dose ◽  
Whole Body ◽  
Eye Lens ◽  
Dose Equivalent ◽  
Retrospective Assessment ◽  
Time Period ◽  
Conversion Coefficients ◽  
Left And Right ◽  
Lens Opacities

Abstract Coefficients converting the readings of the whole body dosemeter worn on the left arm to eye lens doses were determined by analysing the correlations between Hp(10) and Hp(3) values. Doses were measured on a phantom for specific C-arm projections typically used during CA/PCI procedures. In order to estimate the cumulative eye lens doses, conversion coefficients were then applied to the dose records of interventional cardiologists collected in the database of dosimetry service between the years 1995 and 2009. The Hp(10) to Hp(3) conversion coefficients are 0.29 (CV = 34%) and 0.17 (CV = 42%) for left and right eye lens, respectively. However, they can vary from one laboratory to another depending on working technique. From among 61 interventional cardiologists, none exceeded the threshold dose of 0.5 Gy for eye lens opacities. However, 44% of interventional cardiologists were likely to exceed the annual limit of 20 mSv for the most exposed eye at least once in the analysed time period.

Assessment Of Whole Body, Skin and Eye Lens Doses of the Interventional Radiologists At Selected Hospitals in Iran

2021 ◽  
Author(s):  
Z Danaei ◽  
S M Hosseini Pooya ◽  
E Jazayeri Gharehbagh ◽  
S Baradaran
Keyword(s):  
The Body ◽  
Clinical Staff ◽  
Whole Body ◽  
Eye Lens ◽  
Dose Equivalent ◽  
Annual Dose ◽  
Occupational Groups ◽  
Lead Apron ◽  
Eye Lens Dose ◽  
Measured Dose

Abstract High radiation doses to the body may lead to the stochastic/deterministic effects of ionizing radiation on the critical organs as well as causing the cataract in eye lens of the clinical staff in interventional radiology. In this study, the received doses of the eyes, skin and whole body of 38 clinical staff including physicians, residents, nurses and radiotechnologists in cardiac angiography departments in three selected hospitals were assessed using personal dosemeters during two bimonthly dosimetry periods. Moreover, the correlation coefficients among the measured dose components including eye lens dose, skin dose and whole body dose equivalent in both area of under and over their lead-apron were calculated for all these occupational groups. The results show that the occupational annual dose values of the clinical staff are below the annual dose limits recommended by International Commission on Radiation Protection. Furthermore, among the measured dose components, the highest correlation coefficient value was obtained between the eye lens dose and personal dose equivalent measured over the lead apron for all the occupational groups.

Radiation-Induced Lens Opacities among Interventional Cardiologists: Retrospective Assessment of Cumulative Eye Lens Doses

2018 ◽  
Vol 189 (4) ◽  
pp. 399-408 ◽  
Author(s):  
L. Struelens ◽  
J. Dabin ◽  
E. Carinou ◽  
P. Askounis ◽  
O. Ciraj-Bjelac ◽  
...  
Keyword(s):  
Eye Lens ◽  
Retrospective Assessment ◽  
Radiation Induced ◽  
Lens Opacities

scholarly journals Personal dose equivalent conversion coefficients for neutron fluence over the energy range of 20-250 MeV

2009 ◽  
Vol 138 (3) ◽  
pp. 199-204 ◽  
Author(s):  
R. H. Olsher ◽  
T. D. McLean ◽  
A. L. Justus ◽  
R. T. Devine ◽  
M. S. Gadd
Keyword(s):  
Energy Range ◽  
Neutron Fluence ◽  
Dose Equivalent ◽  
Conversion Coefficients

Combinations of nonlabeled, 125I-Labeled, and Anti-Idiotypic Antiplacental Alkaline Phosphatase Monoclonal Antibodies at Experimental Radioimmunotargeting

1997 ◽  
Vol 38 (6) ◽  
pp. 1087-1093 ◽  
Author(s):  
R. Rossi Norrlund ◽  
D. Holback ◽  
L. Johansson ◽  
S.-O. Hietala ◽  
K. Riklund Åhlström
Keyword(s):  
Alkaline Phosphatase ◽  
Tumor Antigens ◽  
Single Injection ◽  
Whole Body ◽  
Kinetic Properties ◽  
Placental Alkaline Phosphatase ◽  
Dose Ratio ◽  
Time Period ◽  
Cell Line Hela ◽  
High Level

Purpose: Placental alkaline phosphatase (PLAP) is a membrane-bound oncofetal antigen that can be used for radioimmunotargeting. Preinjection of nonlabeled monoclonal anti-PLAP antibody (H7) and postinjection of monoclonal anti-idiotypic anti-PLAP antibody (αPH7) were used in order to improve the localization efficacy of 125I-labeled H7 Material and Methods: A human cervix adenocarcinoma cell line (HeLa Hep 2) was inoculated subcutaneously in 24 nude mice. Repeated quantitative radioimmunoscintigraphic recordings were performed on 27 occasions in each of the 24 mice during the observation period which lasted for nearly 3 months. the tumor and nontumor doses were calculated according to the Medical International Radiation Dose Committee formula on the basis of the scintigraphic data Results: All tumors were clearly visualized as early as one day after injection of 125I-labeled H7. the remaining radioactivity was exclusively located in the tumors at days 30–81. as much as 12–16% of the injected dose/g accumulated in the tumors during the first 2 days after injection, and remained stable at this high level for approximately 10 days in all investigated groups. Radioactivity in the whole body was rapidly eliminated during the same time period. the highest tumor/nontumor dose ratio was obtained after a single injection of 125I-labeled H7 Conclusion: Neither a preinjection of nonlabeled H7 nor a postinjection of αPH7 nor a combination of both strategies resulted in improved tumor/nontumor dose ratios compared to a single injection of labeled H7. the monoclonal antibody H7 has a rapid and high uptake, combined with a prolonged retention time in the tumors. the kinetic properties of H7 are different from antibodies targeting intracellular tumor antigens

Coordination of locomotor and cardiorespiratory networks of Lymnaea stagnalis by a pair of identified interneurones

1991 ◽  
Vol 158 (1) ◽  
pp. 37-62 ◽  
Author(s):  
N. I. Syed ◽  
W. Winlow
Keyword(s):  
Body Wall ◽  
Lymnaea Stagnalis ◽  
The Body ◽  
Whole Body ◽  
Pond Snail ◽  
Selective Ablation ◽  
The Central Nervous System ◽  
Body Wall Muscles ◽  
Bilateral Pair ◽  
Left And Right

1. The morphology and electrophysiology of a newly identified bilateral pair of interneurones in the central nervous system of the pulmonate pond snail Lymnaea stagnalis is described. 2. These interneurones, identified as left and right pedal dorsal 11 (L/RPeD11), are electrically coupled to each other as well as to a large number of foot and body wall motoneurones, forming a fast-acting neural network which coordinates the activities of foot and body wall muscles. 3. The left and right sides of the body wall of Lymnaea are innervated by left and right cerebral A cluster neurones. Although these motoneurones have only ipsilateral projections, they are indirectly electrically coupled to their contralateral homologues via their connections with L/RPeD11. Similarly, the activities of left and right pedal G cluster neurones, which are known to be involved in locomotion, are also coordinated by L/RPeD11. 4. Selective ablation of both neurones PeD11 results in the loss of coordination between the bilateral cerebral A clusters. 5. Interneurones L/RPeD11 are multifunctional. In addition to coordinating motoneuronal activity, they make chemical excitatory connections with heart motoneurones. They also synapse upon respiratory motoneurones, hyperpolarizing those involved in pneumostome opening (expiration) and depolarizing those involved in pneumostome closure (inspiration). 6. An identified respiratory interneurone involved in pneumostome closure (visceral dorsal 4) inhibits L/RPeD11 together with all their electrically coupled follower cells. 7. Both L/RPeD11 have strong excitatory effects on another pair of electrically coupled neurones, visceral dorsal 1 and right parietal dorsal 2, which have previously been shown to be sensitive to changes in the partial pressure of environmental oxygen (PO2). 8. Although L/RPeD11 participate in whole-body withdrawal responses, electrical stimulation applied directly to these neurones was not sufficient to induce this behaviour.

ESTIMATION OF UNCERTAINTY IN MEASUREMENT OF DOSE EQUIVALENT AT LABORATORY LEVEL USING CASO4 :Dy-BASED TLD BADGE SYSTEM IN INDIA

2019 ◽  
Vol 188 (2) ◽  
pp. 135-147 ◽  
Author(s):  
S M Pradhan ◽  
D Datta ◽  
Munir S Pathan ◽  
Kshama Srivastava ◽  
T Palani Selvam
Keyword(s):  
Coefficient Of Variation ◽  
Whole Body ◽  
Dose Equivalent ◽  
Radiation Quality ◽  
Variance Model ◽  
Factors Affecting ◽  
Uncertainty In Measurement ◽  
Photon Dose ◽  
Combined Uncertainty ◽  
Quality Coefficient

Abstract The objective of this paper is to estimate the combined uncertainty in the measurement of dose equivalent at laboratory level using CaSO4:Dy-based thermoluminescent dosemeter badge system by including variations in the components of the system. The variability of performance of the system is analysed using random effects one way analysis of variance model. The model enables estimation of the overall variance of the performance of the sampled population. The population in the study comprises all possible indicated dose equivalents on irradiation of dosemeters to a specific dose equivalent and radiation quality. Coefficient of variation and combined uncertainty at 95% level of confidence in the measurement of Hp(10) due to S-Cs radiation quality are found to be 6.6 and 14.3%, respectively, at the dose level of 5.31 mSv. The above parameters in the measurement of in-use quantity, i.e. whole body dose or photon dose equivalent are found to be 7.4 and 16.4%, respectively. The performance of the monitoring system on relative response has been observed to be satisfactory. Various factors affecting the variability of performance of the system are identified for further improvement in coefficient of variation.

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