Symptoms of obstructive sleep apnea are associated with less frequent exercise and worse subjective cognitive function across adulthood

SLEEP ◽  
2021 ◽  
Author(s):  
Miranda G Chappel-Farley ◽  
Bryce A Mander ◽  
Ariel B Neikrug ◽  
Annamarie Stehli ◽  
Bin Nan ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Cognitive Function ◽  
Sleep Quality ◽  
Sleep Problems ◽  
Factor Scores ◽  
Cognitive Complaints ◽  
Exercise Frequency ◽  
Obstructive Sleep ◽  
The Relationship

Abstract Study Objectives To determine whether subjective measures of exercise and sleep are associated with cognitive complaints and whether exercise effects are mediated by sleep. Methods This study analyzed questionnaire data from adults (18-89) enrolled in a recruitment registry. The Cognitive Function Instrument (CFI) assessed cognitive complaints. Medical Outcomes Study Sleep Scale (MOS-SS) subscales and factor scores assessed sleep quality, daytime sleepiness, nighttime disturbance, and insomnia and OSA-like symptoms. Exercise frequency was defined as the weekly number of exercise sessions. Exercise frequency, MOS-SS subscales and factor scores were examined as predictors of CFI Score, adjusting for age, BMI, education, sex, cancer diagnosis, antidepressant usage, psychiatric conditions, and medical comorbidities. ANCOVA examined the relationship between sleep duration groups (short, mid-range, and long) and CFI Score, adjusting for covariates. Mediation by sleep in the exercise-CFI score relationship was tested. Results Data from 2,106 adults were analyzed. Exercise and MOS-SS subscales and factor scores were associated with CFI score. Higher Sleep Adequacy scores were associated with fewer cognitive complaints, whereas higher Sleep Somnolence, Sleep Disturbance, Sleep Problems Index I, Sleep Problems Index II, and factor scores were associated with more cognitive complaints. MOS-SS subscales and factor scores, except Sleep Disturbance and the insomnia factor score, mediated the association between exercise and cognitive complaints. Conclusions The relationship between exercise frequency and subjective cognitive performance is mediated by sleep. In particular, the mediation effect appears to be driven by symptoms possibly suggestive of obstructive sleep apnea which are negatively associated with exercise engagement, sleep quality, daytime sleepiness, and subjective cognitive performance.

Better sleep quality could reinforce the relationship between sleep posture and kidney stone laterality in obstructive sleep apnea patients

Urolithiasis ◽  
2019 ◽  
Vol 48 (3) ◽  
pp. 245-249 ◽  
Author(s):  
Tzu-Yu Chuang ◽  
Yi-Chun Chiu ◽  
Yu-Hua Fan ◽  
Shyh-Chyi Hung ◽  
Wei-Ming Cheng
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Sleep Quality ◽  
Kidney Stone ◽  
Obstructive Sleep ◽  
The Relationship ◽  
Sleep Posture

Obstructive sleep apnea and head and neck neoplasms

2005 ◽  
Vol 132 (5) ◽  
pp. 794-799 ◽  
Author(s):  
Roy Rada
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Head And Neck ◽  
Head And Neck Neoplasms ◽  
Sleep Problems ◽  
Obstructive Sleep ◽  
New Research ◽  
The Relationship

OBJECTIVE: To elaborate the relationship between obstructive sleep apnea (OSA) and head and neck neoplasms (HNN). STUDY DESIGN AND SETTING: A systematic review of the MEDLINE literature. RESULTS: Thirty of 34 articles indexed under OSA and HNN were about neoplasms that presented first as OSA. Four of the articles were about treatment of HNN causing OSA and gave incidences varying from 8% to 92%. Quality of life surveys confirm that patients with malignant HNN have sleep problems. Xerostomia may contribute to these sleep problems, and the role of salivary mucins deserves consideration. CONCLUSIONS: This review of the literature raises several new research questions about the clinical and biological relationships between OSA and HNN. (Otolaryngol Head Neck Surg 2005;132:794-9.)

scholarly journals Sleep quality mediates the relationship between risk of obstructive sleep apnea and acute stress in young adults

2021 ◽  
Author(s):  
Kunal Aggarwal ◽  
Nasreen Akhtar ◽  
Hrudananda Mallick
Keyword(s):  
At Risk ◽  
Obstructive Sleep Apnea ◽  
Young Adults ◽  
Sleep Apnea ◽  
Sleep Quality ◽  
Acute Stress ◽  
Poor Sleep ◽  
Extreme Stress ◽  
Obstructive Sleep ◽  
The Relationship

AbstractPurposeIntermittent hypoxia and transient arousals in obstructive sleep apnea (OSA) can lead to poor sleep quality and acute stress. Rising levels of obesity and increased incidence of OSA in young adults predisposes them to acute stress. We propose a mediation model to assess if risk of OSA is associated with acute stress and if the relationship between risk for OSA and acute stress is mediated by sleep quality.Methods493 healthy individuals (F=237, M=256) from 18-25 years of age (mean age=20.3±1.53 years) were screened for OSA, sleep quality and acute stress using STOP-BANG questionnaire, Pittsburg Sleep Quality Index and American Psychiatry Association’s National Stressful Events Survey Acute Stress Disorder Short Scale (NSESS-S) respectively. Binary and logistic regression were used establish the relationships between the variables. Sobel test for mediation analysis was conducted.Results73 participants (17.3%) were found at an intermediate and high risk of OSA by STOP BANG questionnaire. 79 (16%) participants reported level of stress as ‘None’. Mild, moderate and severe stress was present in 248 (50.3%), 109 (22.1%), 51 (10.3%) and 16 (3.2%) participants respectively. The odds of having severe and extreme stress among those at risk of sleep apnea is 2.18 times higher than that among those not at risk of sleep apnea (OR: 2.18, 95% Confidence Interval: 1.37-3.51). Sobel test established that the relationship between OSA and acute stress is mediated by sleep quality.ConclusionSleep quality mediates the relationship between risk for sleep apnea and acute stress. This highlights the importance of screening for OSA in young adults, particularly young men with high BMI, presenting with high stress levels.

scholarly journals Sleep disturbances in HIV-infected patients associated with depression and high risk of obstructive sleep apnea

2019 ◽  
Vol 7 ◽  
pp. 205031211984226 ◽  
Author(s):  
Jeydith Gutierrez ◽  
Ellen M Tedaldi ◽  
Carl Armon ◽  
Vaidahi Patel ◽  
Rachel Hart ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Sleep Quality ◽  
Sleep Disturbances ◽  
Sleep Problems ◽  
Poor Sleep ◽  
Poor Sleep Quality ◽  
Patient Cohort ◽  
Obstructive Sleep ◽  
Single Question

Objective: To evaluate sleep disturbances in a diverse, contemporary HIV-positive patient cohort and to identify demographic, clinical, and immune correlates. Methods: A convenience sample of 176 patients from a racially and ethnically diverse HIV-positive patient cohort in an urban population. This was a cross-sectional, epidemiologic study. We surveyed participants using multiple standardized instruments to assess depression, sleep quality, and risk for sleep apnea. We analyzed demographic, behavioral, and clinical correlates. Results: A total of 56% of participants were female, 75% Black and 64% had heterosexual HIV risk. The median age was 49 years. Poor sleep quality (Pittsburgh Sleep Quality Index > 5) was reported by 73% of patients and 52% met insomnia diagnosis criteria. A single question about self-reported sleep problems predicted a Pittsburgh Sleep Quality Index > 5 with a sensitivity and specificity of 82% and 81%, respectively. Female sex was significantly associated with higher risk of poor sleep quality, depression, and insomnia, whereas higher risk of obstructive sleep apnea was significantly associated with older age, male sex, obesity (body mass index ⩾ 30 kg/m2), and metabolic comorbidities. High risk for obstructive sleep apnea, high rate of depression, and poor sleep hygiene represent treatment targets for sleep problems in HIV patients. Conclusion: Sleep disturbances were common in this patient cohort, although largely undiagnosed and untreated. Sleep problems are linked to worse disease progression and increased cardiovascular mortality. Screening for sleep problems with a single question had high sensitivity and specificity. In those patients with self-reported sleep problems, screening for obstructive sleep apnea, depression, and sleep hygiene habits should be part of routine HIV care.

scholarly journals Alternate Day Fasting Combined with a Low Carbohydrate Diet: Effect on Sleep Quality, Duration, Insomnia Severity and Risk of Obstructive Sleep Apnea in Adults with Obesity

Nutrients ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 211
Author(s):  
Faiza Kalam ◽  
Kelsey Gabel ◽  
Sofia Cienfuegos ◽  
Mark Ezpeleta ◽  
Eric Wiseman ◽  
...  
Keyword(s):  
Weight Loss ◽  
Obstructive Sleep Apnea ◽  
Sleep Apnea ◽  
Sleep Quality ◽  
Weight Maintenance ◽  
Carbohydrate Diet ◽  
Low Carbohydrate Diet ◽  
Obstructive Sleep ◽  
Low Carbohydrate ◽  
Insomnia Severity

Background: Alternate day fasting combined with a low carbohydrate diet (ADF-LC) is an effective weight loss regimen. Whether the weight loss induced by ADF-LC can improve sleep, remains unknown. Objective: This study examined the effect an ADF-LC diet on sleep quality, duration, insomnia severity and the risk of obstructive sleep apnea. Methods: Adults with obesity (n = 31) participated in ADF (600 kcal “fast day”; ad libitum intake “feast day”) with a low-carbohydrate diet (30% carbohydrates, 35% protein, and 35% fat). The 6-month trial consisted of a 3-month weight loss period followed by a 3-month weight maintenance period. Results: Reductions in body weight (−5 ± 1 kg, p < 0.001) and fat mass (−4 ± 1 kg, p < 0.01) were noted during the weight loss period, and these reductions were sustained during the weight maintenance period. Lean mass and visceral fat remained unchanged. The Pittsburgh Sleep Quality Index (PSQI) score indicated poor sleep quality at baseline (6.4 ± 0.7) with no change by month 3 or 6, versus baseline. ISI score indicated subthreshold insomnia at baseline (8.5 ± 1.0), with no change by month 3 or 6, versus baseline. The percent of subjects with high risk of obstructive sleep apnea at baseline was 45%, with no change by month 3 or 6. Wake time, bedtime, and sleep duration remained unchanged. Conclusion: The ADF-LC diet does not impact sleep quality, duration, insomnia severity or the risk of obstructive sleep apnea in adults with obesity.

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