Blocking Expression of AHR2 and ARNT1 in Zebrafish Larvae Protects Against Cardiac Toxicity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin

2006 ◽  
Vol 94 (1) ◽  
pp. 175-182 ◽  
Author(s):  
D. S. Antkiewicz ◽  
R. E. Peterson ◽  
W. Heideman
Keyword(s):  
Cardiac Toxicity ◽  
Zebrafish Larvae ◽  
Tetrachlorodibenzo P Dioxin

scholarly journals Benoxacor caused developmental and cardiac toxicity in zebrafish larvae

2021 ◽  
Vol 224 ◽  
pp. 112696
Author(s):  
Weixin Zhang ◽  
Jiajie Yan ◽  
Yong Huang ◽  
Ziqin Wang ◽  
Bo Cheng ◽  
...  
Keyword(s):  
Cardiac Toxicity ◽  
Zebrafish Larvae

Cytopathology of Cardiac Tissue from Daunomycin-Treated Mice

1971 ◽  
Vol 29 ◽  
pp. 550-551
Author(s):  
Robert H. Liss ◽  
Frances A. Cotton
Keyword(s):  
Cardiac Tissue ◽  
Cardiac Toxicity ◽  
Drug Distribution ◽  
Personal Communication ◽  
Intravenous Dose ◽  
Single Intravenous Dose ◽  
Physiologic Saline ◽  
Histopathologic Changes ◽  
Distribution Studies ◽  
Lung And Kidney

Daunomycin, an antibiotic used in the clinical management of acute leukemia, produces a delayed, lethal cardiac toxicity. The lethality is dose and schedule dependent; histopathologic changes induced by the drug have been described in heart, lung, and kidney from hamsters in both single and multiple dose studies. Mice given a single intravenous dose of daunomycin (10 mg/kg) die 6-7 days later. Drug distribution studies indicate that the rodents excrete most of a single dose of the drug as daunomycin and metabolite within 48 hours after dosage (M. A. Asbell, personal communication).Myocardium from the ventricles of 6 moribund BDF1 mice which had received a single intravenous dose of daunomycin (10 mg/kg), and from controls dosed with physiologic saline, was fixed in glutaraldehyde and prepared for electron microscopy.

Troponin I as a marker of cardiac toxicity in acute colchicine overdose

2000 ◽  
Vol 18 (6) ◽  
pp. 0743-0744 ◽  
Author(s):  
Michael E. Mullins ◽  
Deborah G. Robertson ◽  
Robert L. Norton
Keyword(s):  
Troponin I ◽  
Cardiac Toxicity ◽  
Colchicine Overdose

Nrf2/HO-1 Mediated Protective Activity of Genistein Against Doxorubicin-Induced Cardiac Toxicity

2019 ◽  
Vol 38 (2) ◽  
pp. 143-152 ◽  
Author(s):  
Miao Chen ◽  
Vijaya Paul Samuel ◽  
Yi Wu ◽  
Minyan Dang ◽  
Yukiat Lin ◽  
...  
Keyword(s):  
Cardiac Toxicity ◽  
Protective Activity
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