scholarly journals Assessment of DNA/chromosome damage in the peripheral blood lymphocytes of workers exposed to indium compounds

2017 ◽  
pp. kfx017 ◽  
Author(s):  
Nan Liu ◽  
Yi Guan ◽  
Ling Xue ◽  
Yan Yu ◽  
Jingwei Xiao ◽  
...  
Keyword(s):  
Peripheral Blood ◽  
Peripheral Blood Lymphocytes ◽  
Chromosome Damage ◽  
Blood Lymphocytes ◽  
Indium Compounds

scholarly journals Genotoxic biomarkers in patients on hemodialiasis

2020 ◽  
Vol 18 (3) ◽  
pp. 367-389
Author(s):  
Natalia V. Eremina ◽  
Andrey D. Durnev
Keyword(s):  
Peripheral Blood ◽  
Human Life ◽  
Peripheral Blood Lymphocytes ◽  
Chromosome Damage ◽  
Literature Information ◽  
Genotoxic Effects ◽  
Blood Lymphocytes ◽  
Genotoxic Damage ◽  
Important Measure

It is generally recognized that genotoxic damage have essential etiopathogenetic significance, and its prevention is an important measure to preserve human life and health. In the framework of this concept, literature information on studies of genotoxic biomarkers in patients with various hemodialysis regiments has been reviewed and summarized, and ways to prevent detectable genotoxicity have been identified. Based on the analysis of the known data, it was concluded that patients of this group have an increased level of DNA and chromosome damage in peripheral blood lymphocytes. Based on the results of individual studies, it was shown that one of the strategies for reducing genotoxicity may be the improvement of hemodialysis therapy methods and regimes, as well as pharmacological and nutritional correction of genotoxic effects.

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