Taylor, Prof. Edwin William, (born 8 June 1929), Louis Block Professor of Molecular Genetics and Cell Biology, University of Chicago, 1984–99, half-time, 1999, now Emeritus (Professor, Department of Biophysics, 1975–99); part-time Research Professor, Department of Cell and Molecular Biology, Northwestern University Medical School, since 2000

In comparison to many other fields of ultrastructural research in Cell Biology, the successful exploration of genes and gene activity with the electron microscope in higher organisms is a late conquest. Nucleic acid molecules of Prokaryotes could be successfully visualized already since the early sixties, thanks to the Kleinschmidt spreading technique - and much basic information was obtained concerning the shape, length, molecular weight of viral, mitochondrial and chloroplast nucleic acid. Later, additonal methods revealed denaturation profiles, distinction between single and double strandedness and the use of heteroduplexes-led to gene mapping of relatively simple systems carried out in close connection with other methods of molecular genetics.

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The Year Book of Orthopedics and Traumatic Surgery, 1954–1955. Edited by Edwardl. Compere, M.D., F.A.C.S., F.I.C.S., Professor and Chairman, Department of Bone and Joint Surgery, Northwestern University Medical School; etc. 7½ × 5⅛ in. Pp. 384, with 193 illustrations. 1955. Chcago: Year Book Publishers Inc. (London: Interscience Publishers Ltd.). 45s

British Journal of Surgery ◽

10.1002/bjs.18004418326 ◽

1956 ◽

Vol 44 (183) ◽

pp. 111-111

Keyword(s):

Medical School ◽

Joint Surgery ◽

Northwestern University ◽

Book Publishers

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Carl Singer (1945-2013) – Life on a Plate: Yeast genetics meetings and micromanipulators

FEMS Yeast Research ◽

10.1093/femsyr/foab003 ◽

2021 ◽

Author(s):

Harry Singer ◽

Terrance G Cooper

Keyword(s):

Molecular Biology ◽

Cell Biology ◽

Cutting Edge ◽

Genetic Maps ◽

Yeast Genetics

Abstract Micromanipulators, more than any other instrument, opened the early doors to developing the powerful genetics of yeast that underlies much of the molecular work today. The ability to separate the spores of a tetrad and analyze their phenotypes generated the genetic maps and biology upon which subsequent cloning, sequencing, cutting edge molecular and cell biology depended. This work describes the development of those micromanipulators from garage to barn to factory and the developer of the sophisticated instruments we use today. For more than 30 years Carl Singer and his family were staunch and generous supporters of the International Conferences on Yeast Genetics and Molecular Biology meetings both in Europe and America. Carl Singer's displays at meetings became a traditional fixture and engaged the appetites of many students and advanced researchers to employ a technique that many perceived as too complicated or difficult, but which he made simple and easy to learn. His experiences also document a sketch of the international yeast meetings, their venues and how they developed through the years.

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