scholarly journals Effect of aging on Rho‐kinase activity and vascular smooth muscle contractility in skeletal muscle resistance arteries

2018 ◽  
Vol 32 (S1) ◽  
Author(s):  
Song Yi Shin ◽  
Samuel Padgham ◽  
Andreea Trache ◽  
Christopher Woodman
Keyword(s):  
Skeletal Muscle ◽  
Smooth Muscle ◽  
Vascular Smooth Muscle ◽  
Kinase Activity ◽  
Rho Kinase ◽  
Resistance Arteries ◽  
Muscle Contractility ◽  
Smooth Muscle Contractility

Low-concentration ouabain does not inhibit noradrenaline-induced contraction of human resistance arteries

1991 ◽  
Vol 81 (s25) ◽  
pp. 525-529 ◽  
Author(s):  
Robin G. Woolfson ◽  
Nicholas T. Richards ◽  
Lucilla Poston
Keyword(s):  
Smooth Muscle ◽  
Vascular Smooth Muscle ◽  
Sodium Pump ◽  
Isometric Tension ◽  
Response Relationship ◽  
Resistance Arteries ◽  
Muscle Contractility ◽  
Smooth Muscle Contractility ◽  
Noradrenaline Concentration ◽  
Low Concentrations

1. Using a Mulvany-Halpern myograph to measure changes in isometric tension, we have investigated the effect of ouabain on noradrenaline-induced contraction of human subcutaneous resistance arteries. 2. Low concentrations of ouabain (10 nmol/l or less) were shown not to alter vascular smooth muscle contractility or sensitivity to noradrenaline. 3. In contrast, higher concentrations of ouabain (100 nmol/l or more) were found to depress vascular smooth muscle contractility and to reduce the sensitivity of the noradrenaline concentration-response relationship. 4. These findings may have implications regarding the presence of an endogenous inhibitor of the sodium pump in essential hypertension and in pregnancy-associated hypertension.

Smoothelin-B is essential for functional vascular smooth muscle contractility

2006 ◽  
Vol 45 (3) ◽  
pp. e104-e105
Author(s):  
P. Niessen ◽  
S. Rensen ◽  
J. van Deursen ◽  
M. Gijbels ◽  
E. Heijman ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Vascular Smooth Muscle ◽  
Muscle Contractility ◽  
Smooth Muscle Contractility

[OP.8C.02] SENESCENCE INCREASES VASCULAR SMOOTH MUSCLE CONTRACTIONS THROUGH INCREASED RHO KINASE ACTIVITY IN FEMALE MOUSE AORTA

2016 ◽  
Vol 34 ◽  
pp. e102
Author(s):  
S. Novella ◽  
X. Vidal-Gómez ◽  
I. Pérez-Monzó ◽  
A. Mompeón ◽  
D. Pérez-Cremades ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Vascular Smooth Muscle ◽  
Female Mouse ◽  
Kinase Activity ◽  
Rho Kinase ◽  
Muscle Contractions ◽  
Mouse Aorta ◽  
Smooth Muscle Contractions
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