scholarly journals G protein‐coupled receptor kinases can enhance beta‐arrestin recruitment to the D 2 dopamine receptor in the absence of receptor phosphorylation

2019 ◽  
Vol 33 (S1) ◽  
Author(s):  
Kayla A. Schardien ◽  
Marta Sanchez Soto ◽  
Blair K.A. Willette ◽  
Elizabeth C. Gonye ◽  
Amy E. Moritz ◽  
...  
Keyword(s):  
Dopamine Receptor ◽  
G Protein ◽  
G Protein Coupled Receptor ◽  
Receptor Phosphorylation ◽  
Receptor Kinases ◽  
G Protein Coupled

G protein‐coupled receptor kinase 2 can enhance beta‐arrestin recruitment to the D 2 dopamine receptor in the absence of receptor phosphorylation

2020 ◽  
Vol 34 (S1) ◽  
pp. 1-1
Author(s):  
Marta Sanchez-Soto ◽  
Kayla A. Schardien ◽  
Laura Inbody ◽  
R. Benjamin Free ◽  
David R. Sibley
Keyword(s):  
Dopamine Receptor ◽  
G Protein ◽  
Receptor Kinase ◽  
G Protein Coupled Receptor ◽  
Receptor Phosphorylation ◽  
G Protein Coupled

scholarly journals G protein-coupled receptor kinases as regulators of dopamine receptor functions

2016 ◽  
Vol 111 ◽  
pp. 1-16 ◽  
Author(s):  
Eugenia V. Gurevich ◽  
Raul R. Gainetdinov ◽  
Vsevolod V. Gurevich
Keyword(s):  
Dopamine Receptor ◽  
G Protein ◽  
G Protein Coupled Receptor ◽  
Receptor Kinases ◽  
G Protein Coupled

scholarly journals G protein‐coupled receptor kinase 2 can enhance β‐arrestin recruitment to the D 2 dopamine receptor in the absence of receptor phosphorylation

2021 ◽  
Vol 35 (S1) ◽  
Author(s):  
Marta Sanchez Soto ◽  
Christopher Dasaro ◽  
Kayla Schardien ◽  
Laura Inbody ◽  
R. Free ◽  
...  
Keyword(s):  
Dopamine Receptor ◽  
G Protein ◽  
Receptor Kinase ◽  
G Protein Coupled Receptor ◽  
Receptor Phosphorylation ◽  
G Protein Coupled

scholarly journals The G Protein-Coupled Receptor Kinases (GRKs) in Chemokine Receptor-Mediated Immune Cell Migration: From Molecular Cues to Physiopathology

Cells ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 75
Author(s):  
Marta Laganà ◽  
Géraldine Schlecht-Louf ◽  
Françoise Bachelerie
Keyword(s):  
G Protein ◽  
Chemokine Receptor ◽  
Immune Cell ◽  
Neutrophil Migration ◽  
G Protein Coupled Receptor ◽  
Receptor Kinases ◽  
Immune Cell Migration ◽  
And Migration ◽  
G Protein Coupled ◽  
Gpcr Desensitization

Although G protein-coupled receptor kinases (GRKs) have long been known to regulate G protein-coupled receptor (GPCR) desensitization, their more recently characterized functions as scaffolds and signalling adapters underscore that this small family of proteins governs a larger array of physiological functions than originally suspected. This review explores how GRKs contribute to the complex signalling networks involved in the migration of immune cells along chemokine gradients sensed by cell surface GPCRs. We outline emerging evidence indicating that the coordinated docking of several GRKs on an active chemokine receptor determines a specific receptor phosphorylation barcode that will translate into distinct signalling and migration outcomes. The guidance cues for neutrophil migration are emphasized based on several alterations affecting GRKs or GPCRs reported to be involved in pathological conditions.

Myocardial and Peripheral Lymphocytic Transcriptomic Dissociation of β-adrenoceptors and G Protein–coupled Receptor Kinases in Heart Transplantation

2009 ◽  
Vol 28 (11) ◽  
pp. 1166-1171 ◽  
Author(s):  
Jaime Agüero ◽  
Luis Almenar ◽  
Pilar D'Ocon ◽  
Eduardo Oliver ◽  
Fermi Montó ◽  
...  
Keyword(s):  
Heart Transplantation ◽  
G Protein ◽  
G Protein Coupled Receptor ◽  
Receptor Kinases ◽  
G Protein Coupled
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