scholarly journals The Influence of Phospholipase A 2 (PLA 2 ) Enzymes on Fatty Acid Release and Oxylipin Formation in Rat Hearts

2021 ◽  
Vol 35 (S1) ◽  
Author(s):  
Anne Mendonca ◽  
Tanja Winter ◽  
Harold Aukema
Keyword(s):  
Fatty Acid ◽  
Phospholipase A ◽  
Rat Hearts ◽  
Fatty Acid Release ◽  
Acid Release ◽  
Phospholipase A 2

scholarly journals Biochemical actions of vasoactive peptide hormones. Time-synchronized activation of lipolysis and decreased fatty-acid release by bradykinin and angiotensin in the perfused rabbit kidney

1980 ◽  
Vol 192 (1) ◽  
pp. 127-131 ◽  
Author(s):  
M Schwartzman ◽  
A Raz
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Time Lag ◽  
Rabbit Kidney ◽  
Subsequent Decrease ◽  
Fatty Acid Release ◽  
Initial Activation ◽  
Acid Release ◽  
Sequential Processes ◽  
Vasoactive Peptide

Bradykinin and angiotensin administered to the isolated perfused rabbit kidney activate two sequential processes: (1) a selective release of the prostaglandin precursor arachidonate with concomitant partial conversion of the arachidonate into prostaglandin E2; (2) activation of a process that leads to decreased release of all fatty acids in the perfusate. There is a time lag of approx. 1 min between the initial activation of the arachidonate-specific deacylation reaction that is coupled to prostaglandin generation, and the subsequent decrease in the release of all fatty acids. This synchronized cycle provides for instant generation of required amounts of prostaglandins and at the same time serves to conserve cellular arachidonate.

Selective fatty acid release from intracellular phospholipids caused by PCBs in rat renal tubular cell cultures

2000 ◽  
Vol 125 (2) ◽  
pp. 117-131 ◽  
Author(s):  
E Sánchez ◽  
M Fernández Santiago ◽  
P López-Aparicio ◽  
M.N Recio ◽  
M.A Pérez-Albarsanz
Keyword(s):  
Fatty Acid ◽  
Cell Cultures ◽  
Tubular Cell ◽  
Renal Tubular Cell ◽  
Fatty Acid Release ◽  
Acid Release ◽  
Renal Tubular

Epinephrine-insulin antagonism on free fatty acid release

1961 ◽  
Vol 201 (5) ◽  
pp. 815-818 ◽  
Author(s):  
John J. Spitzer ◽  
William T. McElroy
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Free Fatty Acid ◽  
Free Fatty Acids ◽  
Blood Sugar ◽  
Drug Administration ◽  
Hepatic Uptake ◽  
Fatty Acid Release ◽  
Plasma Ffa ◽  
Acid Release

The effects of epinephrine or norepinephrine were studied in dogs receiving insulin plus glucose prior to and during administration of the amine. Epinephrine caused a significantly smaller elevation of free fatty acids (FFA) with than without insulin plus glucose administration. Blood sugar responses were quantitatively similar. Epinephrine increased both hepatic uptake of FFA and hepatic release of glucose; these changes were similar to the ones found previously in dogs not receiving insulin plus glucose. The action of norepinephrine on elevating plasma FFA was only slightly and not significantly affected by the administration of insulin plus glucose. When the order of drug administration was reversed, infusion of insulin plus glucose lowered plasma FFA levels and hepatic FFA uptake in animals already receiving either epinephrine or nonepinephrine.

Characterization of the lipolytic pathways that mediate free fatty acid release during Fas/CD95-induced apoptosis

APOPTOSIS ◽  
2005 ◽  
Vol 10 (6) ◽  
pp. 1369-1381 ◽  
Author(s):  
M. Iturralde ◽  
J. Pardo ◽  
E. Lacasa ◽  
G. Barrio ◽  
M. A. Alava ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Free Fatty Acid ◽  
Fatty Acid Release ◽  
Acid Release ◽  
Induced Apoptosis
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