scholarly journals Sonic Hedgehog signaling mediates bone marrow‐derived mesenchymal stem cell proliferation and recruitment

2010 ◽  
Vol 24 (S1) ◽  
Author(s):  
Jessica M Donnelly ◽  
Ambreesh Chawla ◽  
JeanMarie Houghton ◽  
Yana Zavros
Keyword(s):  
Bone Marrow ◽  
Cell Proliferation ◽  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Sonic Hedgehog ◽  
Hedgehog Signaling ◽  
Sonic Hedgehog Signaling ◽  
Stem Cell Proliferation

scholarly journals Overexpression of FABP3 inhibits human bone marrow derived mesenchymal stem cell proliferation but enhances their survival in hypoxia

2014 ◽  
Vol 323 (1) ◽  
pp. 56-65 ◽  
Author(s):  
Suna Wang ◽  
Yifu Zhou ◽  
Oleg Andreyev ◽  
Robert F. Hoyt ◽  
Avneesh Singh ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Cell Proliferation ◽  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Stem Cell Proliferation

scholarly journals Epithelial WNT2B and Desert Hedgehog are necessary for human colonoid regeneration after bacterial cytotoxin injury

2018 ◽  
Author(s):  
Julie G. In ◽  
Jianyi Yin ◽  
Michele Doucet ◽  
Robert N. Cole ◽  
Lauren DeVine ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Stem Cell ◽  
Sonic Hedgehog ◽  
Hedgehog Signaling ◽  
E Coli ◽  
Stem Cell Proliferation ◽  
Epithelial Regeneration ◽  
Desert Hedgehog ◽  
Crypt Hyperplasia

SUMMARYIntestinal regeneration and crypt hyperplasia after radiation or pathogen injury relies on Wnt signaling to stimulate stem cell proliferation. Mesenchymal Wnts are essential for homeostasis and regeneration in mice, but the role of epithelial Wnts remains largely uncharacterized. Using the enterohemorrhagicE. colisecreted cytotoxin, EspP to induce injury to human colonoids, we evaluated a simplified, epithelial regeneration model that lacks mesenchymal Wnts. Here, we demonstrate that epithelial-produced WNT2B is upregulated following injury and essential for regeneration. Hedgehog signaling, specifically activation via the ligand Desert Hedgehog (DHH), but not Indian or Sonic Hedgehog, is another driver of regeneration and modulates WNT2B expression. These findings highlight the importance of epithelial WNT2B and DHH in regulating human colonic regeneration after injury.

scholarly journals Petroleum ether extract of Cissus quadrangularis (Linn.) enhances bone marrow mesenchymal stem cell proliferation and facilitates osteoblastogenesis

Clinics ◽  
2009 ◽  
Vol 64 (10) ◽  
pp. 993-998 ◽  
Author(s):  
Bhagath Kumar Potu ◽  
Kumar MR Bhat ◽  
Muddanna S Rao ◽  
Gopalan Kutty Nampurath ◽  
Mallikarjuna Rao Chamallamudi ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Cell Proliferation ◽  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Petroleum Ether ◽  
Petroleum Ether Extract ◽  
Ether Extract ◽  
Stem Cell Proliferation ◽  
Cissus Quadrangularis

scholarly journals Effects of Exendin-4 on bone marrow mesenchymal stem cell proliferation, migration and apoptosis in vitro

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Hao Zhou ◽  
Dandan Li ◽  
Chen Shi ◽  
Ting Xin ◽  
Junjie Yang ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Cell Proliferation ◽  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Stem Cell Proliferation

scholarly journals Morroniside promotes bone marrow mesenchymal stem cell proliferation in rats

2013 ◽  
Vol 7 (5) ◽  
pp. 1565-1570 ◽  
Author(s):  
NAIWU HU ◽  
SHUJUN REN ◽  
WEI LI ◽  
TAO ZHANG ◽  
CHENGBIN ZHAO
Keyword(s):  
Bone Marrow ◽  
Cell Proliferation ◽  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Stem Cell Proliferation
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