scholarly journals Nonclassical G Protein Coupled Receptor Kinase 5 Regulation of Angiotensin II type 1 Receptor in CATH.a Neurons

2012 ◽  
Vol 26 (S1) ◽  
Author(s):  
Christopher William Engler ◽  
Karla Haack ◽  
Irving Zucker
Keyword(s):  
Angiotensin Ii ◽  
G Protein ◽  
Receptor Kinase ◽  
G Protein Coupled Receptor ◽  
G Protein Coupled

Human dipeptidyl peptidase III regulates G-protein coupled receptor-dependent Ca2+ concentration in human embryonic kidney 293T cells

2016 ◽  
Vol 397 (6) ◽  
pp. 563-569 ◽  
Author(s):  
Subhash C. Prajapati ◽  
Ratnakar Singh ◽  
Shyam S. Chauhan
Keyword(s):  
Angiotensin Ii ◽  
G Protein ◽  
Biological Function ◽  
Dipeptidyl Peptidase ◽  
Luciferase Reporter ◽  
G Protein Coupled Receptor ◽  
Intracellular Ca ◽  
First Time ◽  
G Protein Coupled

Abstract The precise biological function of human dipeptidyl peptidase III (hDPP III) is poorly understood. Using luciferase reporter constructs responsive to change in Ca2+ and/or cAMP and Fura 2-AM fluorometric assay, we show a significant decrease in intracellular Ca2+ following hDPP III overexpression and angiotensin II stimulation in angiotensin II type 1 receptor (G-protein coupled receptor, GPCR) expressing HEK293T cells. Silencing the expression of hDPP III by siRNA reversed the effect of hDPP III overexpression with a concomitant increase in Ca2+. These results, for the first time, show involvement of hDPP III in GPCR dependent Ca2+ regulation in HEK293T cells.

scholarly journals G Protein-Coupled Receptor Kinase 2 Involvement in Desensitization of Corticotropin-Releasing Factor (CRF) Receptor Type 1 by CRF in Murine Corticotrophs

Endocrinology ◽  
2006 ◽  
Vol 147 (1) ◽  
pp. 441-450 ◽  
Author(s):  
Kazunori Kageyama ◽  
Komaki Hanada ◽  
Takako Moriyama ◽  
Takeshi Nigawara ◽  
Satoru Sakihara ◽  
...  
Keyword(s):  
G Protein ◽  
Corticotropin Releasing Factor ◽  
Receptor Type ◽  
Receptor Kinase ◽  
G Protein Coupled Receptor ◽  
G Protein Coupled

scholarly journals Effects of Decreased Renal Cortical Expression of G Protein-Coupled Receptor Kinase 4 and Angiotensin Type 1 Receptors in Rats

2008 ◽  
Vol 31 (7) ◽  
pp. 1455-1464 ◽  
Author(s):  
Junichi YATABE ◽  
Hironobu SANADA ◽  
Sanae MIDORIKAWA ◽  
Shigeatsu HASHIMOTO ◽  
Tsuyoshi WATANABE ◽  
...  
Keyword(s):  
G Protein ◽  
Receptor Kinase ◽  
G Protein Coupled Receptor ◽  
G Protein Coupled ◽  
Angiotensin Type

scholarly journals G Protein-coupled Receptor Kinase and β-Arrestin-mediated Desensitization of the Angiotensin II Type 1AReceptor Elucidated by Diacylglycerol Dynamics

2006 ◽  
Vol 281 (47) ◽  
pp. 36411-36419 ◽  
Author(s):  
Jonathan D. Violin ◽  
Scott M. DeWire ◽  
William G. Barnes ◽  
Robert J. Lefkowitz
Keyword(s):  
Angiotensin Ii ◽  
G Protein ◽  
Receptor Kinase ◽  
G Protein Coupled Receptor ◽  
G Protein Coupled

G protein-coupled receptor kinase (GRK) specificity of endogenous type 1 vasoactive intestinal polvpeptide (VIP) receptor expressed on the surface of HEK 293 cells

2000 ◽  
Vol 118 (4) ◽  
pp. A309
Author(s):  
Michael A. Shetzline ◽  
Julia K. Walker ◽  
Brian M. Curtin ◽  
Richard T. Premont ◽  
Marc G Caron
Keyword(s):  
G Protein ◽  
Receptor Kinase ◽  
G Protein Coupled Receptor ◽  
Hek 293 ◽  
Hek 293 Cells ◽  
293 Cells ◽  
G Protein Coupled ◽  
Vip Receptor

Leveraging NMR and X-ray Data of the Free Ligands to Build Better Drugs Targeting Angiotensin II Type 1 G-Protein Coupled Receptor

2015 ◽  
Vol 23 (1) ◽  
pp. 36-59 ◽  
Author(s):  
Tahsin Kellici ◽  
Dimitrios Ntountaniotis ◽  
Eftichia Kritsi ◽  
Maria Zervou ◽  
Panagiotis Zoumpoulakis ◽  
...  
Keyword(s):  
Angiotensin Ii ◽  
G Protein ◽  
G Protein Coupled Receptor ◽  
X Ray ◽  
G Protein Coupled

scholarly journals G-Protein–Coupled Receptor Mas Is a Physiological Antagonist of the Angiotensin II Type 1 Receptor

Circulation ◽  
2005 ◽  
Vol 111 (14) ◽  
pp. 1806-1813 ◽  
Author(s):  
Evi Kostenis ◽  
Graeme Milligan ◽  
Arthur Christopoulos ◽  
Carlos F. Sanchez-Ferrer ◽  
Silvia Heringer-Walther ◽  
...  
Keyword(s):  
Angiotensin Ii ◽  
G Protein ◽  
G Protein Coupled Receptor ◽  
G Protein Coupled
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