By suppressing the expression of anterior pharynx‐defective‐1α and ‐1β and inhibiting the aggregation of β‐amyloid protein, magnesium ions inhibit the cognitive decline of amyloid precursor protein/presenilin 1 transgenic mice

2015 ◽  
Vol 29 (12) ◽  
pp. 5044-5058 ◽  
Author(s):  
Xin Yu ◽  
Pei‐Pei Guan ◽  
Jing‐Wen Guo ◽  
Yue Wang ◽  
Long‐Long Cao ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Amyloid Precursor Protein ◽  
Cognitive Decline ◽  
Precursor Protein ◽  
Presenilin 1 ◽  
Amyloid Protein ◽  
Magnesium Ions ◽  
Β Amyloid

Reelin in plaques of β-amyloid precursor protein and presenilin-1 double-transgenic mice

2001 ◽  
Vol 316 (3) ◽  
pp. 145-148 ◽  
Author(s):  
Oliver Wirths ◽  
Gerd Multhaup ◽  
Christian Czech ◽  
Véronique Blanchard ◽  
Günter Tremp ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Amyloid Precursor Protein ◽  
Precursor Protein ◽  
Presenilin 1 ◽  
Β Amyloid ◽  
Double Transgenic Mice

Intraneuronal Aβ accumulation precedes plaque formation in β-amyloid precursor protein and presenilin-1 double-transgenic mice

2001 ◽  
Vol 306 (1-2) ◽  
pp. 116-120 ◽  
Author(s):  
Oliver Wirths ◽  
Gerd Multhaup ◽  
Christian Czech ◽  
Véronique Blanchard ◽  
Saliha Moussaoui ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Amyloid Precursor Protein ◽  
Plaque Formation ◽  
Precursor Protein ◽  
Presenilin 1 ◽  
Β Amyloid ◽  
Double Transgenic Mice ◽  
Intraneuronal Aβ

scholarly journals Enhanced accumulation of phosphorylated α-synuclein in double transgenic mice expressing mutant β-amyloid precursor protein and presenilin-1

2007 ◽  
Vol 85 (10) ◽  
pp. 2246-2252 ◽  
Author(s):  
Tomoko Kurata ◽  
Takeshi Kawarabayashi ◽  
Tetsuro Murakami ◽  
Kazunori Miyazaki ◽  
Nobutoshi Morimoto ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Amyloid Precursor Protein ◽  
Precursor Protein ◽  
Presenilin 1 ◽  
Β Amyloid ◽  
Double Transgenic Mice

scholarly journals Intraneuronal APP/Aβ Trafficking and Plaque Formation in β-Amyloid Precursor Protein and Presenilin-1 Transgenic Mice

2006 ◽  
Vol 12 (3) ◽  
pp. 275-286 ◽  
Author(s):  
Oliver Wirths ◽  
Gerd Multhaup ◽  
Christian Czech ◽  
Nicole Feldmann ◽  
Véronique Blanchard ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Amyloid Precursor Protein ◽  
Plaque Formation ◽  
Precursor Protein ◽  
Presenilin 1 ◽  
Β Amyloid

scholarly journals β-Secretase Processing of the β-Amyloid Precursor Protein in Transgenic Mice Is Efficient in Neurons but Inefficient in Astrocytes

1996 ◽  
Vol 271 (49) ◽  
pp. 31407-31411 ◽  
Author(s):  
Jun Zhao ◽  
Lisa Paganini ◽  
Lennart Mucke ◽  
Marissa Gordon ◽  
Larry Refolo ◽  
...  
Keyword(s):  
Transgenic Mice ◽  
Amyloid Precursor Protein ◽  
Precursor Protein ◽  
Β Amyloid
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