Relative Importance of Flow versus  Pressure in Splanchnic Perfusion during Cardiopulmonary Bypass in Rabbits

2000 ◽  
Vol 92 (2) ◽  
pp. 457-457 ◽  
Author(s):  
Olivier Bastien ◽  
Vincent Piriou ◽  
Abdellah Aouifi ◽  
Claire Flamens ◽  
Rhys Evans ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cardiopulmonary Bypass ◽  
Laser Doppler Flowmetry ◽  
Laser Doppler ◽  
Analysis Of Covariance ◽  
Tissue Blood Flow ◽  
Splanchnic Perfusion ◽  
Doppler Flowmetry ◽  
Significant Difference ◽  
Splanchnic Ischemia

Background Decreased gastrointestinal perfusion has been reported during cardiopulmonary bypass (CPB). Conflicting results have been published concerning thresholds of pressure and flow to avoid splanchnic ischemia during CPB. This study compared splanchnic perfusion during independent and randomized variations of CPB pump flow or arterial pressure. Methods Ten rabbits were studied during mild hypothermic (36 degrees C) nonpulsatile CPB using neonatal oxygenators. Simultaneous measurements of tissue blood flow in four different splanchnic areas (gastric, jejunum, ileum, and liver) were performed by laser Doppler flowmetry (LDF) before CPB (T0) and during a 4-step factorial experimental block design. Pressure and flow were alternatively high or low in random order. Results Laser Doppler flowmetry was significantly lower than pre-CPB value but was better preserved (analysis of covariance) in all organs, except liver, when CPB flow was high, whatever the pressure. Splanchnic LDF values in the low- versus high-flow groups expressed as perfusion unit were (mean +/- SD): stomach, 94+/-66 versus 137+/-75; jejunum, 118+/-78 versus 172+/-75; ileum, 95+/-72 versus 146+/-83; and liver, 79+/-72 versus 108+/-118. No significant difference of LDF was observed between the high- and low-pressure groups, whatever the flow, except for liver: stomach, 115+/-64 versus 117+/-83; jejunum, 141+/-80 versus 148+/-83; ileum, 127+/-87 versus 114+/-76; liver, 114+/-88 versus 73+/-70. Conclusion Prevention of splanchnic ischemia during CPB should focus on preservation of high CPB blood flow rather than on high pressure.

scholarly journals Evaluation of the marginal gingival health using laser doppler flowmetry

2006 ◽  
Vol 17 (3) ◽  
pp. 219-222 ◽  
Author(s):  
Hakan Develioglu ◽  
Bülent Kesim ◽  
Aykut Tuncel
Keyword(s):  
Blood Flow ◽  
Laser Doppler Flowmetry ◽  
Laser Doppler ◽  
Plaque Index ◽  
Tissue Blood Flow ◽  
Doppler Flowmetry ◽  
Gingival Health ◽  
Significant Difference ◽  
Clinical Indices ◽  
And Control

The purposes of this study were to compare the gingival blood flow (GBF) in test sites (teeth retaining fixed partial dentures) and control sites (contralateral natural teeth) and investigate whether there is any relationship between clinical indices and GBF values. Twelve healthy subjects (6 females and 6 males) aged 20 to 54 years were enrolled this study. The GBF was measured from the middle point of the marginal gingiva in the test and control sites using laser Doppler flowmetry (LDF). Additionally, plaque index, gingival index and probing depth measurements were recorded. Statistically significant difference (p<0.05) was found between the test and control sites for marginal GBF. In contrast, no significant difference (p>0.05) was found between test and control sites with respect to the clinical indices, except for plaque index. The findings of this study suggest that there is a significant relation between resin-bonded fixed partial dentures with margins located subgingivally and marginal GBF. Clinical indices are helpful to collect information about the clinical health status of gingival tissues, but GBF is a good tool to measure gingival tissue blood flow and assess periodontal health. In conclusion, laser Doppler flowmetry can be used together with clinical indices to evaluate the marginal gingival health.

EFFECT OF CARDIOPULMONARY BYPASS ON URETHRAL BLOOD FLOW AS MEASURED BY LASER DOPPLER FLOWMETRY

1998 ◽  
Vol 160 (6 Part 1) ◽  
pp. 2030-2032 ◽  
Author(s):  
B. ROBERT BAMSHAD ◽  
MICHAEL W. POON ◽  
STEVEN C. STEWART
Keyword(s):  
Blood Flow ◽  
Cardiopulmonary Bypass ◽  
Laser Doppler Flowmetry ◽  
Laser Doppler ◽  
Doppler Flowmetry

The use of laser Doppler flowmetry to evaluate oral soft tissue blood flow in humans: A review

2018 ◽  
Vol 86 ◽  
pp. 58-71 ◽  
Author(s):  
Ayepa Alain Kouadio ◽  
Fabienne Jordana ◽  
N’goran Justin Koffi ◽  
Pierre Le Bars ◽  
Assem Soueidan
Keyword(s):  
Blood Flow ◽  
Soft Tissue ◽  
Laser Doppler Flowmetry ◽  
Laser Doppler ◽  
Tissue Blood Flow ◽  
Doppler Flowmetry ◽  
Oral Soft Tissue

Evaluation of Pulpal Blood Flow Changes in Primary Molars with Physiological Root Resorption by Laser Doppler Flowmetry and Pulse Oximetry

2011 ◽  
Vol 36 (2) ◽  
pp. 139-144 ◽  
Author(s):  
Hüseyin Karayilmaz ◽  
Zuhal Kirzioğlu
Keyword(s):  
Blood Flow ◽  
Pulse Oximetry ◽  
Laser Doppler Flowmetry ◽  
Root Resorption ◽  
Laser Doppler ◽  
Primary Molars ◽  
Primary Molar ◽  
Doppler Flowmetry ◽  
Pulpal Blood Flow ◽  
Significant Difference

Aim: The aim of this study was to undertake a comprehensive quantitative investigation of pulpal blood flow (PBF) changes in human non-carious primary molar teeth with variable degrees of root resorption by Laser Doppler Flowmetry (LDF) and Pulse Oximetry (PO) methods. Materials and Methods: Data was collected from clinically and radiographically healthy 86 mandibular primary molars which have different physiological root resorption levels (PRRLs). PRRLs for each of the teeth were assessed using periapical radiographs and teeth were subdivided into three groups. Results: The LDF values demonstrated a significant difference (p = 0.0001) between all groups although PO did not demonstrate any difference (p = 0.109). Statistical analysis of LDF values demonstrated significant differences between Groups A and C (p = 0.0001) and Groups B and C (p = 0.008). Furthermore, positive correlations were determined between LDF values and PRRL groups (p = 0.0001) and patients' ages (p = 0.0001). Conclusions: In our study, it was observed that the PBF values of human primary molars measured by LDF tended to increase with the progress of physiological root resorption and age. LDF was found to be a more effective method than PO to assess the pulpal vascularity changes of human primary molars.

First Place — Resident Clinical Science Award 1993: A Comparison of Cocaine vs. Lidocaine with Oxymetazoline for Use in Nasal Procedures

1993 ◽  
Vol 109 (4) ◽  
pp. 653-659 ◽  
Author(s):  
Cynthia P. Tarver ◽  
Allen D. Noorily ◽  
Connie S. Sakai
Keyword(s):  
Blood Flow ◽  
Laser Doppler Flowmetry ◽  
Pain Perception ◽  
Clinical Science ◽  
Laser Doppler ◽  
Effective Alternative ◽  
Healthy Male ◽  
Doppler Flowmetry ◽  
Treatment Groups ◽  
Significant Difference

This study compared the degree of vasoconstriction and anesthesia obtained with cocaine vs. that obtained with a mixture of lidocaine and oxymetazoline (lido/oxy) in healthy, male volunteers. Blood flow was evaluated by laser Doppler flowmetry. Anesthesia was measured with Semmes-Weinstein monofilaments, testing both sensation threshold and pain perception. A greater decrease in blood flow was seen after the administration of lido/oxy than after the administration of cocaine. Pain perception change was not significantly different between treatment groups at 10 minutes after removal of the medication-soaked pledget, but lido/oxy caused a greater decrease in pain perception than cocaine after 50 minutes. No significant difference in sensation threshold change was seen between treatment groups. Lidocaine with oxymetazoline is, therefore, believed to be an effective alternative to cocaine for nasal procedures.

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