Specific treatment of Chagas disease: current status and new developments

2001 ◽  
Vol 14 (6) ◽  
pp. 733-741 ◽  
Author(s):  
Julio A. Urbina
2021 ◽  
pp. 1-7
Author(s):  
Karl M. Newell

This paper provides reflections on the progress to date and current status of research in kinesiology. The accompanying overview articles in this special issue of Kinesiology Review show that the contemporary disciplinary/professional foci of kinesiology remain, by and large, the same as the initial research and teaching structures of 50 years ago, as outlined in the inaugural overviews. Nevertheless, within this prevailing disciplinary/professional structure, there have been many new developments in movement-related research, including the juxtaposition of novel alignments and integrations of certain specializations of kinesiology. There is general consensus that the quality and quantity of research in kinesiology have advanced substantially, albeit unevenly, on multiple fronts, both within and between the areas of specialization. The research agenda in kinesiology has benefitted from the growing realization of the centrality of human movement and physical activity in contributing to a healthy lifestyle for individuals and societies.


2008 ◽  
Vol 41 (3) ◽  
pp. 315-319 ◽  

Trypanosoma cruzi infection is often not detected early on or actively diagnosed, partly because most infected individuals are either asymptomatic or oligosymptomatic. Moreover, in most places, neither blood banks nor healthcare units offer diagnostic confirmation or treatment access. By the time patients present clinical manifestations of advanced chronic Chagas disease, specific treatment with current drugs usually has limited effectiveness. Better-quality serological assays are urgently needed, especially rapid diagnostic tests for diagnosis patients in both acute and chronic phases, as well as for confirming that a parasitological cure has been achieved. Some new antigen combinations look promising and it is important to assess which ones are potentially the best, together with their requirements in terms of investigation and development. In August 2007, a group of specialized researchers and healthcare professionals met to discuss the state of Chagas infection diagnosis and to build a consensus for a plan of action to develop efficient, affordable, accessible and easy-to-use diagnostic tests for Chagas disease. This technical report presents the conclusions from that meeting.


2003 ◽  
Vol 36 (1) ◽  
pp. 103-107 ◽  
Author(s):  
Sonia S. Francolino ◽  
Antonio Fernandez Antunes ◽  
Rodolfo Talice ◽  
Rachel Rosa ◽  
Joel Selanikio ◽  
...  

A new case of spontaneous cure of human Chagas' disease is described in Uruguay. An 87-year-old man who had a typical acute phase of Trypanosoma cruzi infection in 1947 and never received specific treatment against the disease, when examined in 1998 revealed several completely negative parasitological and serological tests, including traditional serology, PCR and flow cytometry. As a whole, such findings fulfill the current criteria to define the cure of Chagas' disease. Clinical data suggest the possibility of a benign evolution of Chagas' disease in this case, but the basic findings (slight cardiac and esophageal impairment) could also be due to the advanced age of the patient.


ChemInform ◽  
2015 ◽  
Vol 46 (37) ◽  
pp. no-no
Author(s):  
Erika C. G. Aguieiras ◽  
Elisa D. Cavalcanti-Oliveira ◽  
Denise M. G. Freire

1988 ◽  
Vol 02 (07) ◽  
pp. 939-943 ◽  
Author(s):  
Z. ZOU ◽  
T.C. HSU

We report on the current status of the Resonating-Valence-Bond theory, reviewing recent progress made by the Princeton group. We outline new developments concerning the topology of spinons, the geometric “meron” description, the SU(2) gauge theory for the insulating state and the possible connection between fractional quantum Hall state and an RVB state on a square lattice. The current understanding of the normal metallic and superconducting states is also summarized.


Sign in / Sign up

Export Citation Format

Share Document