Accurate Determination of Metabolic Rates from Dynamic Positron Emission Tomography Data with Very-Low Temporal Resolution

2003 ◽  
Vol 27 (4) ◽  
pp. 597-605 ◽  
Author(s):  
Ralph Buchert ◽  
Jörg van den Hoff ◽  
Janos Mester
1987 ◽  
Vol 7 (4) ◽  
pp. 510-512 ◽  
Author(s):  
Campbell Clark ◽  
Michael Hayden ◽  
Susan Hollenberg ◽  
David Li ◽  
A. Jon Stoessl

This article outlines a simple method for estimating the degree of cerebral atrophy and subsequent experimental control for the effects of cerebral atrophy on regional metabolic values measured with positron emission tomography, It is suggested that rather than correcting derived values for atrophy, less potential error is introduced by experimentally controlling for regional atrophy when possible, By treating the derived metabolic rates and the measure of atrophy as two separate variables, it is also possible to establish whether there actually is a demonstrable relationship between the two measures.


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