Helicobacter pylori-Associated Peptic Ulcer in Heterotopic Gastric Mucosa Within Ileal Duplication

1994 ◽  
Vol 18 (2) ◽  
pp. 133-135 ◽  
Author(s):  
Edy Stermer ◽  
Daniel Hardoff ◽  
Eli Zuckerman ◽  
Ines Miselevich
2019 ◽  
Vol 12 ◽  
pp. 117954761984608
Author(s):  
Thomas Surya Suhardja ◽  
Hock Kua ◽  
Zoltan Hrabovszky

Meckel diverticulum is the most common congenital abnormality of the gastrointestinal system. Although most Meckel diverticula are asymptomatic, they can also present with bleeding, obstruction, or perforation. Helicobacter pylori is pathognomonic for the development of a peptic ulcer. We present a case report of a patient with a Meckel diverticulum with Helicobacter pylori colonising its heterotopic gastric mucosa. This is a rare histopathologic finding. We also reviewed the literature of other similar cases published in English.


1994 ◽  
Vol 36 (2) ◽  
pp. 171-175 ◽  
Author(s):  
Y. YAMASHIRO ◽  
S. OGUCHI ◽  
Y. OTSUKA ◽  
S. NAGATA ◽  
T. SHIOYA ◽  
...  

Helicobacter ◽  
2002 ◽  
Vol 7 (4) ◽  
pp. 245-249 ◽  
Author(s):  
Sadatoshi Ishibashi ◽  
Ryuichi Iwakiri ◽  
Ryo Shimoda ◽  
Hibiki Ootani ◽  
Seiji Kawasaki ◽  
...  

1994 ◽  
Vol 179 (5) ◽  
pp. 1653-1658 ◽  
Author(s):  
J L Telford ◽  
P Ghiara ◽  
M Dell'Orco ◽  
M Comanducci ◽  
D Burroni ◽  
...  

The gram negative, microaerophilic bacterium Helicobacter pylori colonizes the human gastric mucosa and establishes a chronic infection that is tightly associated with atrophic gastritis, peptic ulcer, and gastric carcinoma. Cloning of the H. pylori cytotoxin gene shows that the protein is synthesized as a 140-kD precursor that is processed to a 94-kD fully active toxin. Oral administration to mice of the purified 94-kD protein caused ulceration and gastric lesions that bear some similarities to the pathology observed in humans. The cloning of the cytotoxin gene and the development of a mouse model of human gastric disease will provide the basis for the understanding of H. pylori pathogenesis and the development of therapeutics and vaccines.


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