Prognostic value of ventricular arrhythmias in hypertensive patients

1997 ◽  
Vol 15 (11) ◽  
pp. 1357-1358
Author(s):  
M Galinier ◽  
S Balanescu ◽  
J Fourcade ◽  
M Dorobantu ◽  
P Massabuau ◽  
...  
1993 ◽  
Vol 18 (1) ◽  
pp. 63-79
Author(s):  
Sylvie Robichaud-Ekstrand

Many clinical factors influence the 1-year prognosis in myocardial infarction (MI) patients. The most important clinical determinants are the left ventricular dysfunction, myocardial ischemia, and complex ventricular arrhythmias. Some authors have found an independent prognostic value of complex ventricular arrhythmias, while others consider that ventricular arrhythmias predict future cardiac events only if associated with low ejection fractions. Other factors that have 1-year prognostic value are the following: a previous MI, a history of angina at least 3 months preceding the infarct, postmyocardial angina, and the criteria that indicate to the practitioner whether MI patients are medically ineligible for stress testing. There still remain controversies in regard to the predictive value of certain variables such as the site, type, and extension of the MI, the presence of complex ventricular arrhythmias, exercise-induced hypotension, ST segment elevation, and the electrical provocation of dangerous arrhythmias. Key words: cardiac rehabilitation, postinfarct mortality and morbidity, cardiac events predictors, postinfarct prognostic stratification


2018 ◽  
Vol 36 (Supplement 1) ◽  
pp. e59-e60
Author(s):  
P.-Y. Courand ◽  
A. Grandjean ◽  
C. Mouly-Bertin ◽  
C. Berge ◽  
B. Harbaoui ◽  
...  

2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
T T Le ◽  
J Bryant ◽  
B Ang ◽  
B Su ◽  
S Cook ◽  
...  

Abstract Funding Acknowledgements National Medical Research Council BACKGROUND Hypertensive left ventricular hypertrophy (LVH) is associated with increased cardiovascular events. The authors previously developed the Remodeling Index (RI) that incorporated LV volume and wall-thickness in a single measure of advanced hypertrophy in hypertensive patients. PURPOSE This study examined the mechanisms and prognostic potential of the RI in reference with current LVH classifications. METHODS Cardiovascular magnetic resonance (CMR) was performed in 400 asymptomatic hypertensive patients. The newly derived RI ([(EDV)^1/3]/t; where EDV is LV end-diastolic volume and t is the maximal wall thickness across 16 myocardial segments) stratified hypertensive patients into 3 groups: without LVH, LVH with normal RI (LVH_Normal-RI) and LVH with low RI (LVH_Low-RI). The primary outcome was a composite of all-cause mortality, acute coronary syndromes, strokes and decompensated heart failure. RESULTS LVH_Low-RI was associated with increased LV mass index, fibrosis burden, impaired myocardial function and elevated biochemical markers of myocardial injury and wall stress. Over 18.3 ± 7.0 months (601.3 patient-years), patients with LVH_Low-RI had more than a 5-fold increase in adverse events compared to those with LVH_Normal-RI (11.6 events/100patient-years versus 2.0 events/100 patient-years, respectively; log-rank P < 0.001; Figure A). The RI provided incremental prognostic value over and above a model consisting of clinical variables and LVH (P = 0.02). Conversely concentric and eccentric LVH were associated with adverse prognosis (4.5 events/100patient-years versus 6.0 events/100patient-years, respectively; log-rank P = 0.62) that was similar as the natural history of hypertensive LVH (5.1 events/100patient-years). CONCLUSIONS The RI provides mechanistic insights and prognostic value that improves risk-stratification of hypertensive LVH. Abstract P962 Figure.


1997 ◽  
Vol 15 (12) ◽  
pp. 1779-1783 ◽  
Author(s):  
Michel Galinier ◽  
Serban Balanescu ◽  
Joelle Fourcade ◽  
Maria Dorobantu ◽  
Serge Boveda ◽  
...  

2003 ◽  
Vol 145 (1) ◽  
pp. 139-146 ◽  
Author(s):  
Sara Partington ◽  
Jonathan Myers ◽  
Shaun Cho ◽  
Victor Froelicher ◽  
Sung Chun

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