scholarly journals PREVALENCE OF SUBCLINICAL VITAMIN K DEFICIENCY IN CHOLESTATIC LIVER DISEASE

2006 ◽  
Vol 43 (4) ◽  
pp. E35-E36
Author(s):  
Jennifer Strople ◽  
Glenda Lovell ◽  
James Heubi
Keyword(s):  
Liver Disease ◽  
Vitamin K ◽  
Cholestatic Liver Disease ◽  
Vitamin K Deficiency ◽  
K Deficiency ◽  
Subclinical Vitamin

Vitamin K Deficiency

PEDIATRICS ◽  
1985 ◽  
Vol 75 (2) ◽  
pp. 373-374
Author(s):  
NATHANIEL R. PAYNE ◽  
DUANE K. HASEGAWA
Keyword(s):  
Liver Disease ◽  
High Risk ◽  
Vitamin K ◽  
Late Onset ◽  
Cholestatic Liver Disease ◽  
Hemorrhagic Disease ◽  
Vitamin K Deficiency ◽  
Antitrypsin Deficiency ◽  
K Deficiency

In Reply.— We agree with Aballi that a combination of factors placed our patient1 at high risk for vitamin K deficiency during her first month of life. These factors include decreased intestinal absorption of vitamin K due to the cholestatic liver disease of α-1-antitrypsin deficiency and a diet consisting solely of breast milk which is known to have little vitamin K. Aballi correctly points out the lack of data on the role of vitamin K in preventing late-onset hemorrhagic disease.

Prevalence of subclinical vitamin K deficiency in Thai newborns: relationship to maternal phylloquinone intakes and delivery risk

2009 ◽  
Vol 95 (2) ◽  
pp. F104-F108 ◽  
Author(s):  
A. Chuansumrit ◽  
T. Plueksacheeva ◽  
S. Hanpinitsak ◽  
S. Sangwarn ◽  
S. Chatvutinun ◽  
...  
Keyword(s):  
Vitamin K ◽  
Vitamin K Deficiency ◽  
K Deficiency ◽  
Subclinical Vitamin

Vitamin K Deficiency in Newborns: A Case Report in α-1-Antitrypsin Deficiency and a Review of Factors Predisposing to Hemorrhage

PEDIATRICS ◽  
1984 ◽  
Vol 73 (5) ◽  
pp. 712-716
Author(s):  
Nathaniel R. Payne ◽  
Duane K. Hasegawa
Keyword(s):  
Prothrombin Time ◽  
Vitamin K ◽  
Partial Thromboplastin Time ◽  
Signs And Symptoms ◽  
Serum Bilirubin Level ◽  
Intracerebral Hematoma ◽  
Cholestatic Liver Disease ◽  
Vitamin K Deficiency ◽  
Antitrypsin Deficiency ◽  
K Deficiency

A 4-week-old, breast-fed female infant appeared healthy until signs and symptoms of CNS deterioration suddenly occurred. At presentation the infant was found to have a left-sided parietal intracerebral hematoma, markedly prolonged prothrombin time, and partial thromboplastin time, normal platelet count, and jaundice with a total and direct serum bilirubin level of 5.4 mg/dL and 2.6 mg/dL, respectively. Vitamin K1 and fresh frozen plasma returned the prothrombin time and partial thromboplastin time to normal values within 18 hours, suggesting that the infant had severe vitamin K deficiency complicated by intracerebral hemorrhage. Evaluation of the infant's direct hyperbilirubinemia led to the diagnosis of homozygous (pi-type ZZ [PiZZ]) α-1-antitrypsin deficiency. The clinical circumstances predisposing to vitamin K deficiency in newborns and infants are discussed. Based on our observations in this case, we suggest that cholestatic liver disease should be suspected when unexplained vitamin K deficiency occurs in early infancy. The role of vitamin K in hemostasis and the laboratory diagnosis of vitamin K deficiency are discussed as they apply to the evaluation of hemorrhage in newborns and infants.

Subclinical Vitamin K Deficiency in Hemodialysis Patients

2007 ◽  
Vol 49 (3) ◽  
pp. 432-439 ◽  
Author(s):  
Rachel M. Pilkey ◽  
A. Ross Morton ◽  
Michael B. Boffa ◽  
Curtis Noordhof ◽  
Andrew G. Day ◽  
...  
Keyword(s):  
Vitamin K ◽  
Hemodialysis Patients ◽  
Vitamin K Deficiency ◽  
K Deficiency ◽  
Subclinical Vitamin

PIVKA-II plasma levels as markers of subclinical vitamin K deficiency in term infants

2012 ◽  
Vol 25 (9) ◽  
pp. 1660-1663 ◽  
Author(s):  
F. Dituri ◽  
G. Buonocore ◽  
A. Pietravalle ◽  
F. Naddeo ◽  
M. Cortesi ◽  
...  
Keyword(s):  
Vitamin K ◽  
Plasma Levels ◽  
Vitamin K Deficiency ◽  
Term Infants ◽  
K Deficiency ◽  
Subclinical Vitamin

scholarly journals Factor VII Antibody-neutralizing Material in Hereditary and Acquired Factor VII Deficiency

Blood ◽  
1971 ◽  
Vol 38 (1) ◽  
pp. 1-8 ◽  
Author(s):  
SCOTT H. GOODNIGHT ◽  
DONALD I. FEINSTEIN ◽  
BJARNE ØSTERUD ◽  
SAMUEL I. RAPAPORT
Keyword(s):  
Liver Disease ◽  
Vitamin K ◽  
Factor Vii ◽  
Vitamin K Deficiency ◽  
Present Evidence ◽  
Hereditary Factor ◽  
Factor Vii Deficiency ◽  
Coagulant Activity ◽  
K Deficiency

Abstract Evidence is provided for the existence of at least two types of hereditary factor VII deficiency. In one type there is synthesis of a protein which neutralizes a factor VII antibody but lacks coagulant activity. In the second type, no factor VII antibody neutralizing material is present. Evidence is also provided for the existence of two types of acquired factor VII deficiency. Apparently, low factor VII activity in liver disease results from decreased synthesis of factor VII protein. In contrast, warfarin administration or vitamin K deficiency leads to the synthesis of factor VII protein that lacks clotting activity.

Fetal intracranial hemorrhage due to maternal subclinical vitamin K deficiency associated with long-term eating disorder

2018 ◽  
Vol 45 (2) ◽  
pp. 461-465 ◽  
Author(s):  
Genichiro Sotodate ◽  
Atsushi Matsumoto ◽  
Yu Konishi ◽  
Yukiko Toya ◽  
Mikiya Endo ◽  
...  
Keyword(s):  
Eating Disorder ◽  
Intracranial Hemorrhage ◽  
Vitamin K ◽  
Vitamin K Deficiency ◽  
K Deficiency ◽  
Subclinical Vitamin
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