Therapeutic Implications Of Recent Advances in Cystic Fibrosis

1995 ◽  
Vol 20 (6) ◽  
pp. 304???308 ◽  
Author(s):  
Kenneth R. White ◽  
Cindy L. Munro ◽  
Rita H. Pickler
Author(s):  
Rishika Dhapola ◽  
Subhendu Shekhar Hota ◽  
Phulen Sarma ◽  
Anusuya Bhattacharyya ◽  
Bikash Medhi ◽  
...  

2018 ◽  
Vol 32 (7) ◽  
pp. 732-740 ◽  
Author(s):  
Clément E Lemercier ◽  
Devin B Terhune

Background: Recent research on psychedelics and hypnosis demonstrates the value of both methods in the treatment of a range of psychopathologies with overlapping applications and neurophenomenological features. The potential of harnessing the power of suggestion to influence the phenomenological response to psychedelics toward more therapeutic action has remained unexplored in recent research and thereby warrants empirical attention. Aims: Here we aim to elucidate the phenomenological and neurophysiological similarities and dissimilarities between psychedelic states and hypnosis in order to revisit how contemporary knowledge may inform their conjunct usage in psychotherapy. Methods: We review recent advances in phenomenological and neurophysiological research on psychedelics and hypnosis, and we summarize early investigations on the coupling of psychedelics and hypnosis in scientific and therapeutic contexts. Results/outcomes: We highlight commonalities and differences between psychedelics and hypnosis that point to the potential efficacy of combining the two in psychotherapy. We propose multiple research paths for coupling these two phenomena at different stages in the preparation, acute phase and follow-up of psychedelic-assisted psychotherapy in order to prepare, guide and integrate the psychedelic experience with the aim of enhancing therapeutic outcomes. Conclusions/interpretation: Harnessing the power of suggestion to modulate response to psychedelics could enhance their therapeutic efficacy by helping to increase the likelihood of positive responses, including mystical-type experiences.


Prescriber ◽  
2016 ◽  
Vol 27 (11) ◽  
pp. 19-24
Author(s):  
Danny Buckland

2020 ◽  
Vol 15 (3) ◽  
pp. 174-186
Author(s):  
Antonella Tosco ◽  
Valeria R. Villella ◽  
Valeria Raia ◽  
Guido Kroemer ◽  
Luigi Maiuri

Since the identification of Cystic Fibrosis (CF) as a disease in 1938 until 2012, only therapies to treat symptoms rather than etiological therapies have been used to treat the disease. Over the last few years, new technologies have been developed, and gene editing strategies are now moving toward a one-time cure. This review will summarize recent advances in etiological therapies that target the basic defect in the CF Transmembrane Receptor (CFTR), the protein that is mutated in CF. We will discuss how newly identified compounds can directly target mutated CFTR to improve its function. Moreover, we will discuss how proteostasis regulators can modify the environment in which the mutant CFTR protein is synthesized and decayed, thus restoring CFTR function. The future of CF therapies lies in combinatory therapies that may be personalized for each CF patient.


2018 ◽  
Vol 07 (03) ◽  
Author(s):  
Faisal Qaisar ◽  
Anum Habib ◽  
Noor Muhammad ◽  
Zia ur Rehman

1994 ◽  
Vol 70 (822) ◽  
pp. 247-251 ◽  
Author(s):  
G. Santis ◽  
D. Geddes

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