Variation at the Beta-1Adrenoceptor Gene Locus is Associated with Left Ventricular Mass in Endurance Athletes

2004 ◽  
Vol 36 (Supplement) ◽  
pp. S100
Author(s):  
Bernd M. Wolfarth ◽  
Johannes Scherr ◽  
Helga Duerr ◽  
Susanne Muehlbauer
Keyword(s):  
Left Ventricular Mass ◽  
Gene Locus ◽  
Left Ventricular ◽  
Endurance Athletes ◽  
Ventricular Mass

Variation at the Beta-1Adrenoceptor Gene Locus is Associated with Left Ventricular Mass in Endurance Athletes

2004 ◽  
Vol 36 (Supplement) ◽  
pp. S100
Author(s):  
Bernd M. Wolfarth ◽  
Johannes Scherr ◽  
Helga Duerr ◽  
Susanne Muehlbauer
Keyword(s):  
Left Ventricular Mass ◽  
Gene Locus ◽  
Left Ventricular ◽  
Endurance Athletes ◽  
Ventricular Mass

Insulin action on heart and skeletal muscle glucose uptake in weight lifters and endurance athletes

1999 ◽  
Vol 276 (4) ◽  
pp. E706-E711 ◽  
Author(s):  
Teemu O. Takala ◽  
Pirjo Nuutila ◽  
Juhani Knuuti ◽  
Matti Luotolahti ◽  
Hannele Yki-Järvinen
Keyword(s):  
Skeletal Muscle ◽  
Glucose Uptake ◽  
Left Ventricular Mass ◽  
Left Ventricular ◽  
Endurance Athletes ◽  
Whole Body ◽  
Euglycemic Hyperinsulinemic Clamp ◽  
Ventricular Mass ◽  
Weight Lifters ◽  
Skeletal Muscle Glucose Uptake

There are no studies comparing myocardial metabolism between endurance- and resistance-trained athletes. We used 2-deoxy-2-[18F]fluoro-d-glucose and positron emission tomography combined with the euglycemic hyperinsulinemic clamp technique to compare the ability of insulin to stimulate myocardial, skeletal muscle, and whole body glucose uptake between weight lifters ( n = 8), endurance athletes ( n = 8), and sedentary men ( n = 9). Maximal aerobic power (ml ⋅ kg− 1⋅ min− 1) was higher in the endurance athletes (71 ± 2, P < 0.001) than the weight lifters (42 ± 2) and the sedentary men (42 ± 2). Skeletal muscle glucose uptake (μmol ⋅ kg muscle− 1⋅ min− 1) was enhanced in the endurance athletes (125 ± 16, P < 0.01) but was similar in weight lifters (59 ± 12) and sedentary (63 ± 7) men. The rate of glucose uptake per unit mass of myocardium (μmol ⋅ kg− 1⋅ min− 1) was similarly decreased in endurance athletes (544 ± 50) and weight lifters (651 ± 45) compared with sedentary men (1,041 ± 78, P < 0.001 vs. endurance athletes and weight lifters). Both groups of athletes had increased left ventricular mass. Consequently, total left ventricular glucose uptake was comparable in all groups. These data demonstrate that aerobic but not resistance training is associated with enhanced insulin sensitivity in skeletal muscle. Despite this, cardiac changes are remarkably similar in weight lifters and endurance athletes and are characterized by an increase in left ventricular mass and diminished insulin-stimulated glucose uptake per heart mass.

Left ventricular mass as determined by magnetic resonance imaging in male endurance athletes

1988 ◽  
Vol 62 (4) ◽  
pp. 301-305 ◽  
Author(s):  
Martin C. Milliken ◽  
James Stray-Gundersen ◽  
Ronald M. Peshock ◽  
Jose Katz ◽  
Jere H. Mitchell
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Left Ventricular Mass ◽  
Left Ventricular ◽  
Endurance Athletes ◽  
Resonance Imaging ◽  
Ventricular Mass

COMPARISON OF LEFT VENTRICULAR MASS TO LEAN BODY MASS RATIOS IN ENDURANCE ATHLETES

1986 ◽  
Vol 18 (supplement) ◽  
pp. S59
Author(s):  
M. C. Milliken ◽  
R. Peshock ◽  
J. Katz ◽  
J. Stray-Gundersen ◽  
J. H. Mitchell
Keyword(s):  
Left Ventricular Mass ◽  
Lean Body Mass ◽  
Body Mass ◽  
Left Ventricular ◽  
Endurance Athletes ◽  
Ventricular Mass ◽  
Mass Ratios

Left ventricular mass, geometry, and filling in endurance athletes: association with exercise blood pressure

1997 ◽  
Vol 82 (2) ◽  
pp. 531-537 ◽  
Author(s):  
Jouko Karjalainen ◽  
Matti Mäntysaari ◽  
Matti Viitasalo ◽  
Urho Kujala
Keyword(s):  
Blood Pressure ◽  
Left Ventricular Mass ◽  
Left Ventricular ◽  
Endurance Athletes ◽  
Peak Exercise ◽  
Low Grade ◽  
Isometric Handgrip ◽  
Ventricular Mass ◽  
Lv Mass ◽  
Exercise Blood Pressure

Karjalainen, Jouko, Matti Mäntysaari, Matti Viitasalo, and Urho Kujala. Left ventricular mass, geometry, and filling in endurance athletes: association with exercise blood pressure. J. Appl. Physiol. 82(2): 531–537, 1997.—We studied whether left ventricular (LV) mass and concentricity [relative myocardial volume (RMV)] are associated with exercise blood pressure (BP) in athletes. LV structure and filling were evaluated by Doppler echocardiography and BP in maximal bicycle ergometry and isometric handgrip tests on 32 male endurance athletes and 15 age-matched controls. Indexed LV mass was 145 ± 14 (SD) g/m in athletes and 93 ± 20 g/m in controls. Mass was not associated with BP at rest or in low-grade exercise, but with heavier exercise loads this association strengthened in athletes, being maximal at peak exercise ( r = 0.65 for mass and 0.58 for indexed mass; P < 0.001). Multivariate analysis indicated that BP at peak exercise accounted for 34% and the amount of training for an additional 11% of the variance in indexed LV mass. RMV was 21% larger in athletes. Only the increase in systolic BP during handgrip explained significantly (19%) the variance in RMV. LV filling velocities were not associated with mass, RMV, or BP. We conclude that in endurance athletes LV mass is associated with BP in heavy dynamic exercise and LV concentricity with BP response in static exercise.

Abstract #330: Insulin Resistance, Cardiac Output and Left Ventricular Mass in Different Degrees of Obesity

2006 ◽  
Vol 12 ◽  
pp. 6-7
Author(s):  
Juan Ybarra ◽  
Josep Maria Pou ◽  
Teresa Doñate ◽  
Monica Isart ◽  
Jaime Pujadas
Keyword(s):  
Insulin Resistance ◽  
Cardiac Output ◽  
Left Ventricular Mass ◽  
Left Ventricular ◽  
Ventricular Mass

The association of ankle brachial index with left ventricular hypertrophy and left ventricular mass index: the Dong-gu study

VASA ◽  
2013 ◽  
Vol 42 (4) ◽  
pp. 284-291 ◽  
Author(s):  
Seong-Woo Choi ◽  
Hye-Yeon Kim ◽  
Hye-Ran Ahn ◽  
Young-Hoon Lee ◽  
Sun-Seog Kweon ◽  
...  
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Left Ventricular Mass ◽  
Ventricular Hypertrophy ◽  
Left Ventricular Mass Index ◽  
Ankle Brachial Index ◽  
Intima Media Thickness ◽  
Left Ventricular ◽  
Baseline Survey ◽  
Ventricular Mass Index ◽  
Ventricular Mass

Background: To investigate the association between ankle-brachial index (ABI), left ventricular hypertrophy (LVH) and left ventricular mass index (LVMI) in a general population. Patients and methods: The study population consisted of 8,246 people aged 50 years and older who participated in the baseline survey of the Dong-gu Study conducted in Korea between 2007 and 2010. Trained research technicians measured LV mass using mode M ultrasound echocardiography and ABI using an oscillometric method. Results: After adjustment for risk factors and common carotid artery intima-media thickness (CCA-IMT) and the number of plaques, higher ABIs (1.10 1.19, 1.20 - 1.29, and ≥ 1.30) were significantly and linearly associated with high LVMI (1.10 - 1.19 ABI: β, 3.33; 95 % CI, 1.72 - 4.93; 1.20 - 1.29 ABI: β, 6.51; 95 % CI, 4.02 - 9.00; ≥ 1.30 ABI: β, 14.83; 95 % CI, 6.18 - 23.48). An ABI of 1.10 - 1.19 and 1.20 - 1.29 ABI was significantly associated with LVH (1.10 - 1.19 ABI: OR, 1.35; 95 % CI, 1.19 - 1.53; 1.20 - 1.29 ABI: OR, 1.59; 95 % CI, 1.31 - 1.92) and ABI ≥ 1.30 was marginally associated with LVH (OR, 1.73; 95 % CI, 0.93 - 3.22, p = 0.078). Conclusions: After adjustment for other cardiovascular variables and CCA-IMT and the number of plaques, higher ABIs are associated with LVH and LVMI in Koreans aged 50 years and older.

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