Phase I/II clinical trial of the humanized anti-EGF-r monoclonal antibody h-R3 labelled with 99mTc in patients with tumour of epithelial origin

Nuclear Medicine Communications ◽

10.1097/00006231-200512000-00002 ◽

2005 ◽

Vol 26 (12) ◽

pp. 1049-1057 ◽

Author(s):

Leonel A. Torres ◽

Alejandro Perera ◽

Juan F. Batista ◽

Abel Hern??ndez ◽

Tania Crombet ◽

...

Keyword(s):

Clinical Trial ◽

Monoclonal Antibody ◽

Phase I ◽

Epithelial Origin

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Alirocumab for hyperlipidemia: physiology of PCSK9 inhibition, pharmacodynamics and Phase I and II clinical trial results of a PCSK9 monoclonal antibody

Future Cardiology ◽

10.2217/fca.13.107 ◽

2014 ◽

Vol 10 (2) ◽

pp. 183-199 ◽

Author(s):

Eli M Roth ◽

Philip Diller

Keyword(s):

Clinical Trial ◽

Monoclonal Antibody ◽

Phase I ◽

Pcsk9 Inhibition ◽

Clinical Trial Results ◽

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A randomized phase I clinical trial comparing the pharmacokinetic, safety, and immunogenicity of potential biosimilar recombinant human HER2 monoclonal antibody for injection and trastuzumab in healthy Chinese adults

Expert Opinion on Investigational Drugs ◽

10.1080/13543784.2020.1770226 ◽

2020 ◽

Vol 29 (7) ◽

pp. 755-762

Author(s):

Jiaxue Wang ◽

Suping Niu ◽

Wenliang Dong ◽

Li Wei ◽

Lun Ou ◽

...

Keyword(s):

Clinical Trial ◽

Monoclonal Antibody ◽

Phase I ◽

Phase I Clinical Trial ◽

Chinese Adults ◽

Healthy Chinese

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Correction for Scott et al., A phase I clinical trial with monoclonal antibody ch806 targeting transitional state and mutant epidermal growth factor receptors

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.0708144104 ◽

2007 ◽

Vol 104 (40) ◽

pp. 15965-15965 ◽

Keyword(s):

Clinical Trial ◽

Monoclonal Antibody ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Phase I ◽

Growth Factor Receptors ◽

Phase I Clinical Trial ◽

Epidermal Growth Factor Receptors ◽

Transitional State ◽

Epidermal Growth

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Pre-final analysis of first-in-human, first-in-class, phase I clinical trial of CNTO 888, a human monoclonal antibody to the CC-chemokine ligand 2 (CCL2) in patients (pts) with advanced solid tumors.

Journal of Clinical Oncology ◽

10.1200/jco.2010.28.15_suppl.2548 ◽

2010 ◽

Vol 28 (15_suppl) ◽

pp. 2548-2548 ◽

Author(s):

M. D. Forster ◽

A. Patnaik ◽

S. K. Sandhu ◽

K. Papadopoulos ◽

B. J. Tromp ◽

...

Keyword(s):

Clinical Trial ◽

Monoclonal Antibody ◽

Phase I ◽

Solid Tumors ◽

Human Monoclonal Antibody ◽

Final Analysis ◽

Advanced Solid Tumors ◽

Chemokine Ligand ◽

Cc Chemokine Ligand 2 ◽

Chemokine Ligand 2

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A phase I clinical trial with monoclonal antibody ch806 targeting transitional state and mutant epidermal growth factor receptors

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.0611693104 ◽

2007 ◽

Vol 104 (10) ◽

pp. 4071-4076 ◽

Author(s):

A. M. Scott ◽

F.-T. Lee ◽

N. Tebbutt ◽

R. Herbertson ◽

S. S. Gill ◽

...

Keyword(s):

Clinical Trial ◽

Monoclonal Antibody ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Phase I ◽

Growth Factor Receptors ◽

Phase I Clinical Trial ◽

Epidermal Growth Factor Receptors ◽

Transitional State ◽

Epidermal Growth

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Faculty Opinions recommendation of Regulatory approval and a first-in-human phase I clinical trial of a monoclonal antibody produced in transgenic tobacco plants.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725618825.793517604 ◽

2016 ◽

Author(s):

Keith Davis

Keyword(s):

Clinical Trial ◽

Monoclonal Antibody ◽

Phase I ◽

Transgenic Tobacco ◽

Regulatory Approval ◽

Phase I Clinical Trial ◽

Transgenic Tobacco Plants ◽

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Preliminary results of an escalating dose phase I clinical trial of the anti-EGFR monoclonal antibody nimotuzumab in combination with external radiotherapy in patients diagnosed with stage IIb, III or IV non-small cell lung cancer unsuitable for radical therapy

Journal of Clinical Oncology ◽

10.1200/jco.2008.26.15_suppl.3037 ◽

2008 ◽

Vol 26 (15_suppl) ◽

pp. 3037-3037 ◽

Author(s):

D. G. Bebb ◽

A. M. Brade ◽

C. Smith ◽

S. Rorke ◽

I. Sherman

Keyword(s):

Lung Cancer ◽

Clinical Trial ◽

Monoclonal Antibody ◽

Phase I ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

External Radiotherapy ◽

Small Cell Lung ◽

Radical Therapy

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Preclinical pharmacokinetics, interspecies scaling, and pharmacokinetics of a Phase I clinical trial of TTAC-0001, a fully human monoclonal antibody against vascular endothelial growth factor 2

Drug Design Development and Therapy ◽

10.2147/dddt.s150241 ◽

2018 ◽

Vol Volume 12 ◽

pp. 495-504 ◽

Author(s):

Weon Sup Lee ◽

Sang Ryeol Shim ◽

Seon Young Lee ◽

Jin San Yoo ◽

Sung Kweon Cho

Keyword(s):

Clinical Trial ◽

Monoclonal Antibody ◽

Vascular Endothelial Growth Factor ◽

Growth Factor ◽

Phase I ◽

Human Monoclonal Antibody ◽

Interspecies Scaling ◽

Vascular Endothelial ◽

Preclinical Pharmacokinetics ◽

Endothelial Growth Factor

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PHASE-I CLINICAL TRIAL OF MONOCLONAL ANTIBODY IN TREATMENT OF GASTROINTESTINAL TUMOURS

10.1016/s0140-6736(82)91811-6 ◽

1982 ◽

Vol 319 (8275) ◽

pp. 762-765 ◽

Author(s):

HenryF. Sears ◽

Jeffrey Mattis ◽

Dorothee Herlyn ◽

Pekka Häyry ◽

Barbara Atkinson ◽

...

Keyword(s):

Clinical Trial ◽

Monoclonal Antibody ◽

Phase I ◽

Phase I Clinical Trial ◽

Gastrointestinal Tumours

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Preclinical and phase I clinical trial of blockade of IL-15 using Mik 1 monoclonal antibody in T cell large granular lymphocyte leukemia

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.0509575103 ◽

2005 ◽

Vol 103 (2) ◽

pp. 401-406 ◽

Author(s):

J. C. Morris ◽

J. E. Janik ◽

J. D. White ◽

T. A. Fleisher ◽

M. Brown ◽

...

Keyword(s):

Clinical Trial ◽

Monoclonal Antibody ◽

T Cell ◽

Phase I ◽

Phase I Clinical Trial ◽

Large Granular Lymphocyte ◽

Large Granular Lymphocyte Leukemia

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