Toxic Shock Syndrome Caused by Group B Streptococcus

1999 ◽  
Vol 8 (9) ◽  
pp. 458-460 ◽  
Author(s):  
Moe Moe Cheng ◽  
Chatrchai Watanakunakorn
Keyword(s):  
Toxic Shock Syndrome ◽  
Group B Streptococcus ◽  
Toxic Shock ◽  
Group B

An Emerging Infection: Streptococcal Toxic Shock-Like Syndrome Caused By Group B Streptococcus (GBS), Streptococcus Agalactiae

2020 ◽  
Vol 154 (Supplement_1) ◽  
pp. S140-S140
Author(s):  
F Rajack ◽  
A Afsari ◽  
A M Ramadan ◽  
T J Naab
Keyword(s):  
Soft Tissue ◽  
Necrotizing Fasciitis ◽  
Streptococcus Agalactiae ◽  
Group A Streptococcus ◽  
Multiorgan Failure ◽  
Group B Streptococcus ◽  
Stage Iii ◽  
Streptococcal Toxic Shock Syndrome ◽  
Toxic Shock ◽  
Group B

Abstract Introduction/Objective Streptococcus agalactiae, Group B Streptococcus (GBS), is a major cause of neonatal sepsis and infections in pregnant women. However, incidence of invasive GBS infections has more than doubled in the last two decades with highest risk in adults 65 years or older. Other risk factors are diabetes, malignancy, and immunocompromised state. Bacteremia and skin soft tissue infections are the most common invasive infections in nonpregnant adults. Rarely GBS infection has a fulminating pyrogenic exotoxin-mediated course characterized by acute onset, multiorgan failure, shock, and sometimes death, referred to as toxic shock-like syndrome. Methods A 77-year-old hypertensive female with uncontrolled type 2 diabetes mellitus and a history of bilateral foot ulcers presented to the hospital in probable septic shock. Clinical diagnosis of necrotizing fasciitis was made and she underwent bilateral lower limb amputations. Results Grossly soft tissue appeared gray. Microscopically fascia was necrotic without neutrophils present and Gram stain revealed sheets of Gram positive cocci. These findings reflected histopathologic Stage III necrotizing fasciitis, which is associated with 47% mortality. Autopsy showed a similar histology of Stage III necrotizing fasciitis involving the surgical stump. Erythema and desquamation of the upper limbs bilaterally and multi-organ failure met the clinical picture of Streptococcal Toxic Shock Syndrome (STSS) and fulfilled the criteria for TSS due to Group A Streptococcus (GAS), defined by The Working Group on Severe Streptococcal Infections. Conclusion Group B Streptococcal Toxic Shock-Like Syndrome may have a similar outcome to STSS caused by GAS and other pathogens and, in limited studies, mortality has been 30% or greater.

scholarly journals Group B Streptococcal Toxic Shock Syndrome and covR/S Mutations Revisited

2017 ◽  
Vol 23 (1) ◽  
pp. 150-152 ◽  
Author(s):  
Parham Sendi ◽  
Muad Abd el Hay ◽  
Claudia M. Brandt ◽  
Barbara Spellerberg
Keyword(s):  
Toxic Shock Syndrome ◽  
Streptococcal Toxic Shock Syndrome ◽  
Toxic Shock ◽  
Group B

scholarly journals 260. A Rare Case of Severe Group B Streptococcal Infection with Toxic Shock-like Syndrome and Diffuse Metastatic Infection

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S129-S130
Author(s):  
Ali M Ayyash ◽  
Ly Tran ◽  
Charlie Ervin ◽  
Rahul Sampath ◽  
Teresa Campanile
Keyword(s):  
Septic Arthritis ◽  
Group B Streptococcus ◽  
Whole Body ◽  
Toxic Shock ◽  
The Past ◽  
Metastatic Infection ◽  
Wide Range ◽  
Severe Group ◽  
Group B ◽  
The Right

Abstract Background The incidence of invasive Group B streptococcal (GBS) infection has been increasing in the past decade and is currently at 10.9 cases per 100,000 population. GBS toxic shock-like syndrome is rare, with few cases reported over the past decade. The presumed etiology is the production of an uncharacterized pyrogenic toxin by certain strains. Methods We present a unique case of invasive GBS infection complicated by severe GBS-mediated toxic shock-like syndrome (TSLS) and diffuse metastatic infection. Results A 62-year-old obese male with diabetes mellitus presented with pain, swelling, and redness of the right shoulder and ankle for one week after a fall. Vitals were remarkable for tachycardia to 106 BPM and fever of 101°F with labs showing a leukocytosis to 23,500 u/L. The patient was started on ceftriaxone IV but continued to develop worsening fever, leukocytosis, encephalopathy, diffuse extremity pain, and whole-body macular erythema at 48 hours. Blood cultures grew GBS and TSLS was suspected. Adjunct clindamycin was started. MRI of the extremities demonstrated abscesses of the right levator scapulae, posterior scalene, brachioradialis, and right ankle. MRI of the spine showed epidural abscesses at L3-L5 and septic arthritis of the spinal facets at L4-L5. Operative abscess removal with joint washouts were performed by neurosurgery and orthopedics, and the patient symptomatically improved within 2 weeks on IV ceftriaxone. He was subsequently continued on cefazolin for 10 weeks and did well at follow-up. Right elbow showing a characteristic flat, macular erythema of toxic shock-like syndrome. Left arm with macular erythema. MRI showing spinal epidural abscesses at L3-L5 spinal levels (arrows). Conclusion Invasive metastatic Group B Streptococcus infection in non-pregnant adults presenting with TSLS is rare. To our knowledge, there has never been a case of GBS infection causing TSLS with rapidly developing florid metastatic infection including epidural abscess development, septic arthritis, and musculoskeletal abscesses. This case highlights the wide range of infectious possibilities associated with severe GBS infection. Disclosures All Authors: No reported disclosures

Streptococcal and staphylococcal infections

2019 ◽  
pp. 373-376
Keyword(s):  
Staphylococcus Aureus ◽  
Toxic Shock Syndrome ◽  
Specific Information ◽  
Toxic Shock ◽  
Human Host ◽  
Staphylococcal Infections ◽  
Group A ◽  
Genitourinary Medicine ◽  
Group B ◽  
In Pregnancy

Streptococcal and staphylococcal infections provides an overview of the pathology, relevant to genitourinary medicine, caused by these common bacteria. Each section gives a broad overview of the carriage and transmission of streptococci and staphylococci in the human host followed by information on genital infections. The section on streptococci contains information on Group A and Group B beta haemolytic streptococci and includes specific information pertaining to Group B beta haemolytic streptococci in pregnancy. The section on staphylococci concentrates on Staphylococcus aureus and includes specific information on, Panton–Valentine leucocidin-positive (PVL) infection, as well as the presentation, aetiology, and management of toxic shock syndrome (TSS).

Evaluation of streptococcal toxic shock-like syndrome caused by group B streptococcus in adults in Japan between 2009 and 2013

2015 ◽  
Vol 21 (3) ◽  
pp. 207-211 ◽  
Author(s):  
Tadayoshi Ikebe ◽  
Kazuki Chiba ◽  
Tomoko Shima ◽  
Chieko Masuda ◽  
Rumi Okuno ◽  
...  
Keyword(s):  
Group B Streptococcus ◽  
Toxic Shock ◽  
Group B

scholarly journals Postoperative Complications Followed by Septoplasty Comparison between Conventional Nasal Packing and Glove Finger Pack

2012 ◽  
Vol 5 (1) ◽  
pp. 11-13 ◽  
Author(s):  
Aamir Yousuf ◽  
Zafarullah Beigh ◽  
Manzoor Ahmad Malik ◽  
Rafiq Ahmad
Keyword(s):  
Postoperative Complications ◽  
Toxic Shock Syndrome ◽  
Nasal Packing ◽  
Septal Perforation ◽  
Toxic Shock ◽  
Glove Finger ◽  
Group A ◽  
Group B ◽  
Gauze Pack

ABSTRACT Objective Objective of this study is to compare complications in postseptoplasty patients using conventional nasal packing and glove finger packing. Materials and methods In our study 95 patients who underwent septoplasty were enrolled and written consent taken for the study among these 95 patients, 50 patients were put in group A and 45 patients in group B. In group A patients glove finger packing was done and in group B patients conventional packing using medicated gauze was done and postoperative complications like postoperative pain, hemorrhage, septal perforation, toxic shock syndrome, septal hematoma, septal deviation and synechia/adhesion bands were compared between two groups, follow-up was done for both groups for 3 weeks. Result Our study showed that their was significantly less pain in group A patients and also their was less incidence of synechia in group A patients as compared to group B patients, their was not much difference in other complications. Conclusion Our results point out that glove finger pack has more advantage than conventional medicated gauze pack. We recommend use of glove finger pack after septoplasty procedure. How to cite this article Beigh Z, Yousuf A, Malik MA, Ahmad R. Postoperative Complications Followed by Septoplasty Comparison between Conventional Nasal Packing and Glove Finger Pack. Clin Rhinol Int J 2012;5(1):11-13.

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