Role of P300 auditory event-related potentials in evaluating auditory processing disorders

2005 ◽  
Vol 58 (7) ◽  
pp. 49 ◽  
Author(s):  
Sridhar Krishnamurti
Keyword(s):  
Auditory Processing ◽  
Event Related Potentials ◽  
Auditory Processing Disorders ◽  
Auditory Event ◽  
Related Potentials ◽  
Auditory Event Related Potentials

scholarly journals Effects of intensity, attention and medication on auditory-evoked potentials in patients with fibromyalgia

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
N. Samartin-Veiga ◽  
A. J. González-Villar ◽  
Y. Triñanes ◽  
C. Gómez-Perretta ◽  
M. T. Carrillo-de-la-Peña
Keyword(s):  
Auditory Processing ◽  
Auditory Evoked Potentials ◽  
Event Related Potentials ◽  
Pathophysiological Mechanism ◽  
Auditory Event ◽  
Significant Relationships ◽  
Sensory Modalities ◽  
Related Potentials ◽  
Auditory Event Related Potentials

AbstractFibromyalgia (FM) has been associated to an increased processing of somatosensory stimuli, but its generalization to other sensory modalities is under discussion. To clarify this, we studied auditory event-related potentials (AEPs) to stimuli of different intensity in patients with FM and healthy controls (HCs), considering the effects of attention mechanisms and medication. We performed two experiments: In study 1 (n = 50 FM, 60 HCs), the stimuli were presented randomly within the sequence; in study 2 (n = 28 FM, 30 HCs), they were presented in blocks of the same intensity. We analyzed intensity and group effects on N1-P2 amplitude and, only for the FM group, the effect of medication and the correlation between AEPs and clinical variables. Contrary to the expectation, the patients showed a trend of reduced AEPs to the loudest tones (study 1) or no significant differences with the HCs (study 2). Medication with central effects significantly reduced AEPs, while no significant relationships between the N1-P2 amplitude/intensity function and patients’ symptoms were observed. The findings do not provide evidence of augmented auditory processing in FM. Nevertheless, given the observed effect of medication, the role of sensory amplification as an underlying pathophysiological mechanism in fibromyalgia cannot be discarded.

Auditory Event-Related Potentials in the Assessment of Auditory Processing Disorders: A Pilot Study

2003 ◽  
Vol 34 (1) ◽  
pp. 23-29 ◽  
Author(s):  
A. Liasis ◽  
D.-E. Bamiou ◽  
P. Campbell ◽  
T. Sirimanna ◽  
S. Boyd ◽  
...  
Keyword(s):  
Pilot Study ◽  
Auditory Processing ◽  
Event Related Potentials ◽  
Auditory Processing Disorders ◽  
Auditory Event ◽  
Related Potentials ◽  
Auditory Event Related Potentials

scholarly journals Sequential Effects of Increasing Propofol Sedation on Frontal and Temporal Cortices as Indexed by Auditory Event-related Potentials

2004 ◽  
Vol 100 (3) ◽  
pp. 617-625 ◽  
Author(s):  
Wolfgang Heinke ◽  
Ramona Kenntner ◽  
Thomas C. Gunter ◽  
Daniela Sammler ◽  
Derk Olthoff ◽  
...  
Keyword(s):  
Auditory Cortex ◽  
Cognitive Functions ◽  
Auditory Processing ◽  
Primary Auditory Cortex ◽  
Event Related Potentials ◽  
Sequential Effects ◽  
Auditory Event ◽  
Propofol Sedation ◽  
Related Potentials ◽  
Auditory Event Related Potentials

Background It is an open question whether cognitive processes of auditory perception that are mediated by functionally different cortices exhibit the same sensitivity to sedation. The auditory event-related potentials P1, mismatch negativity (MMN), and early right anterior negativity (ERAN) originate from different cortical areas and reflect different stages of auditory processing. The P1 originates mainly from the primary auditory cortex. The MMN is generated in or in the close vicinity of the primary auditory cortex but is also dependent on frontal sources. The ERAN mainly originates from frontal generators. The purpose of the study was to investigate the effects of increasing propofol sedation on different stages of auditory processing as reflected in P1, MMN, and ERAN. Methods The P1, the MMN, and the ERAN were recorded preoperatively in 18 patients during four levels of anesthesia adjusted with target-controlled infusion: awake state (target concentration of propofol 0.0 microg/ml), light sedation (0.5 microg/ml), deep sedation (1.5 microg/ml), and unconsciousness (2.5-3.0 microg/ml). Simultaneously, propofol anesthesia was assessed using the Bispectral Index. Results Propofol sedation resulted in a progressive decrease in amplitudes and an increase of latencies with a similar pattern for MMN and ERAN. MMN and ERAN were elicited during sedation but were abolished during unconsciousness. In contrast, the amplitude of the P1 was unchanged by sedation but markedly decreased during unconsciousness. Conclusion The results indicate differential effects of propofol sedation on cognitive functions that involve mainly the auditory cortices and cognitive functions that involve the frontal cortices.

scholarly journals The Cross-Modal Suppressive Role of Visual Context on Speech Intelligibility: An ERP Study

2020 ◽  
Vol 10 (11) ◽  
pp. 810
Author(s):  
Stanley Shen ◽  
Jess R. Kerlin ◽  
Heather Bortfeld ◽  
Antoine J. Shahin
Keyword(s):  
Speech Intelligibility ◽  
High Reliability ◽  
Word Meaning ◽  
Event Related Potentials ◽  
Auditory Event ◽  
Related Potentials ◽  
The Cross ◽  
Auditory Erps ◽  
Auditory Event Related Potentials

The efficacy of audiovisual (AV) integration is reflected in the degree of cross-modal suppression of the auditory event-related potentials (ERPs, P1-N1-P2), while stronger semantic encoding is reflected in enhanced late ERP negativities (e.g., N450). We hypothesized that increasing visual stimulus reliability should lead to more robust AV-integration and enhanced semantic prediction, reflected in suppression of auditory ERPs and enhanced N450, respectively. EEG was acquired while individuals watched and listened to clear and blurred videos of a speaker uttering intact or highly-intelligible degraded (vocoded) words and made binary judgments about word meaning (animate or inanimate). We found that intact speech evoked larger negativity between 280–527-ms than vocoded speech, suggestive of more robust semantic prediction for the intact signal. For visual reliability, we found that greater cross-modal ERP suppression occurred for clear than blurred videos prior to sound onset and for the P2 ERP. Additionally, the later semantic-related negativity tended to be larger for clear than blurred videos. These results suggest that the cross-modal effect is largely confined to suppression of early auditory networks with weak effect on networks associated with semantic prediction. However, the semantic-related visual effect on the late negativity may have been tempered by the vocoded signal’s high-reliability.

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