A11485 Impact of family history of hypertension and diabetes on heart rate variability in women

Abstract Background Cardiovascular disease is one of the leading causes of death globally with hypertension being a primary cause of premature death from this disease process. Individuals with a family history of cardiovascular disease and hypertension are at a greater risk for developing the same sequela. Autonomic cardiac control is important in the level of cardiac function. One intervention that is effective in improving cardiovascular function is heart rate variability biofeedback training. The purpose of our study was to determine the effectiveness of heart rate biofeedback training on HRV and blood pressure in individuals with a family history of cardiovascular disease. Methods Thirty-four participants (76.5% female, 22.7 ± 4.3 years) completed a baseline assessment and training using an established short-term HRV protocol followed by two weeks of at-home paced breathing employing a smartphone application. The participants were then reassessed in a biofeedback clinic. Results The participants physiological measures showed a significant increase in means between pre and post intervention of SDNN (t (32) = 2.177, p =.037) and TP, (t (32) = 2.327 p = .026). Correlation noted a medium effect on diastolic blood pressure and high frequency heart rate variability, F, r = .41, n =33, p < .05. A multiple regression with all predictor variables in the model found no significance with diastolic and systolic blood pressure. Conclusions The findings from this pilot study demonstrated that a two-week paced breathing intervention may assist in reducing heart rate and diastolic blood pressure while improving heart rate variability.

Download Full-text

Influence of gender and family history of hypertension on autonomic control of heart rate, diastolic function and brain natriuretic peptide

Journal of Hypertension ◽

10.1097/00004872-200101000-00019 ◽

2001 ◽

Vol 19 (1) ◽

pp. 143-148 ◽

Cited By ~ 27

Author(s):

Maria Vittoria Pitzalis ◽

Massimo Iacoviello ◽

Francesco Massari ◽

Pietro Guida ◽

Roberta Romito ◽

...

Keyword(s):

Heart Rate ◽

Family History ◽

Brain Natriuretic Peptide ◽

Diastolic Function ◽

Natriuretic Peptide ◽

Autonomic Control ◽

History Of ◽

Family History Of Hypertension

Download Full-text

A Possible Early Alteration of Autonomic Activity Assessed by Heart Rate Variability in Saudi Offspring of Type 2 Diabetic Patients

Saudi Journal of Internal Medicine ◽

10.32790/sjim.2011.1.2.4 ◽

2011 ◽

Vol 1 (2) ◽

pp. 17-23

Author(s):

Daad H. Akbar ◽

Maha A. Hegazi ◽

Hanan A. Al Kadi ◽

Maimona M. Ahmad

Keyword(s):

Diabetes Mellitus ◽

Insulin Resistance ◽

Type 2 Diabetes ◽

Heart Rate ◽

Heart Rate Variability ◽

Type 2 Diabetes Mellitus ◽

Family History ◽

Family History Of Diabetes ◽

History Of

Background and Objectives: To evaluate cardiac autonomic function in non-diabetic offspring of Type 2 diabetes mellitus patients through assessment of heart rate variability. Autonomic dysfunction was reported in glucose tolerant on insulin-resistant offspring of Type 2 diabetes mellitus subjects. No data is available on cardiac autonomic dysfunction in Saudi offspring of Type 2 diabetes mellitus. Subject and Methods: Ninety-seven subjects with family history and 30 subjects with no family history of diabetes mellitus as a control group were studied. Anthropometric and biochemical characteristics (fasting blood glucose, lipids, and insulin resistance) were measured. Heart rate variability parameters were recorded. Results: No significant differences in the anthropometric, biochemical or heart rate variability parameters between the group with positive family history of diabetes mellitus and the control group. Subjects with positive family history of diabetes mellitus were split into 2 groups as per the presence or absence of insulin resistance. Insignificantly, an increased sympathetic tone was seen in Type 2 diabetes mellitus offspring with insulin resistance as compared to those without it. Body mass index, waist circumference, waist to hip ratio, total cholesterol, triglyceride, and fasting insulin and fasting blood glucose were also significantly higher in the insulin resistance group. Conclusion: There was a high prevalence of insulin resistance among the young subjects with positive family history of diabetes. Thus, had an increased sympathetic activity compared to those who were insulin sensitive. This study confirms the early autonomic dysfunction in offspring of Type 2 diabetes mellitus subjects previously reported in other non-Saudi populations.

Download Full-text

A Possible Early Alteration of Autonomic Activity Assessed by Heart Rate Variability in Saudi Offspring of Type 2 Diabetic Patients

Saudi Journal of Internal Medicine ◽

10.32790/sjim.1.2.4 ◽

2011 ◽

Vol 1 (2) ◽

pp. 17-23

Author(s):

Daad H. Akbar ◽

Maha A. Hegazi ◽

Hanan A. Al Kadi ◽

Maimona M. Ahmad

Keyword(s):

Diabetes Mellitus ◽

Insulin Resistance ◽

Type 2 Diabetes ◽

Heart Rate ◽

Heart Rate Variability ◽

Type 2 Diabetes Mellitus ◽

Family History ◽

Family History Of Diabetes ◽

History Of

Background and Objectives: To evaluate cardiac autonomic function in non-diabetic offspring of Type 2 diabetes mellitus patients through assessment of heart rate variability. Autonomic dysfunction was reported in glucose tolerant on insulin-resistant offspring of Type 2 diabetes mellitus subjects. No data is available on cardiac autonomic dysfunction in Saudi offspring of Type 2 diabetes mellitus. Subject and Methods: Ninety-seven subjects with family history and 30 subjects with no family history of diabetes mellitus as a control group were studied. Anthropometric and biochemical characteristics (fasting blood glucose, lipids, and insulin resistance) were measured. Heart rate variability parameters were recorded. Results: No significant differences in the anthropometric, biochemical or heart rate variability parameters between the group with positive family history of diabetes mellitus and the control group. Subjects with positive family history of diabetes mellitus were split into 2 groups as per the presence or absence of insulin resistance. Insignificantly, an increased sympathetic tone was seen in Type 2 diabetes mellitus offspring with insulin resistance as compared to those without it. Body mass index, waist circumference, waist to hip ratio, total cholesterol, triglyceride, and fasting insulin and fasting blood glucose were also significantly higher in the insulin resistance group. Conclusion: There was a high prevalence of insulin resistance among the young subjects with positive family history of diabetes. Thus, had an increased sympathetic activity compared to those who were insulin sensitive. This study confirms the early autonomic dysfunction in offspring of Type 2 diabetes mellitus subjects previously reported in other non-Saudi populations.

Download Full-text

Effect of exercise on heart rate recovery index in normotensive offspring with family history of hypertension

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20181263 ◽

2018 ◽

Vol 6 (4) ◽

pp. 1101 ◽

Cited By ~ 2

Author(s):

Amrendra Jha ◽

Prajwal Karki ◽

Ritika Agrahari ◽

Neha Kumari

Keyword(s):

Heart Rate ◽

Family History ◽

Heart Rate Recovery ◽

Autonomic System ◽

Step Test ◽

Cardiovascular Risks ◽

Maximum Heart Rate ◽

Recovery Index ◽

History Of ◽

Family History Of Hypertension

Background: The relationship between autonomic system and cardiovascular mortality is significant and this study can be used to study the hereditary risk that an individual carries to develop any autonomic dysfunction and its effect on cardiovascular status. In this study, we aimed to investigate the heart rate recovery index and prevalence of cardiovascular risks in subjects with hypertensive parents.Methods: A total of 30 subjects and 30 healthy controls were recruited in the study. Their anthropometrical and cardiovascular parameters were recorded. Heart rate, blood pressure, weight and height of subjects were measured and BMI calculated. After 3 min step test heart rate will be measured in 1, 2, 3 and 5 minute and heart rate recovery index calculated by subtracting maximum heart rate achieved during exercise by heart rate measured in 1,2,3 and 5 minute. The heart rate recovery index (HRRI) is calculated by extracting the maximum heart rate during treadmill stress testing from the heart rate.Results: The 1st minute HRRI was not significantly different in the groups (43.87±11.54 and 43.00±18.77 respectively, p=0.88). Likewise, the 2nd minute HRRI (50.07±10.38and49.07±16.32 respectively, p=0.843), 3rd minute HRRI (53.33±12.72 and 53.60±17.56 respectively, p=0.962), 4th minute HRRI (55.07±13.25 and 54.60±14.73 respectively, p= 0.928) and 5th minute HRRI (56.33±14.58 and 54.87±14.93 respectively, p=0.788) were also not significantly different.Conclusions: Findings of this study suggest that in the absence high arterial pressure and other comorbidities, a family history of hypertension is not accompanied by dysfunction of autonomic system.

Download Full-text

Sex and family history of cardiovascular disease influence heart rate variability during stress among healthy adults

Journal of Psychosomatic Research ◽

10.1016/j.jpsychores.2018.04.011 ◽

2018 ◽

Vol 110 ◽

pp. 54-60 ◽

Cited By ~ 1

Author(s):

Charles F. Emery ◽

Catherine M. Stoney ◽

Julian F. Thayer ◽

DeWayne Williams ◽

Andrew Bodine

Keyword(s):

Cardiovascular Disease ◽

Heart Rate ◽

Heart Rate Variability ◽

Family History ◽

Healthy Adults ◽

History Of

Download Full-text

Does Smoking Affect Blood Pressure and Heart Rate?

European Journal of Cardiovascular Nursing ◽

10.1016/j.ejcnurse.2005.03.004 ◽

2005 ◽

Vol 4 (4) ◽

pp. 286-289 ◽

Cited By ~ 33

Author(s):

Saafan A. Al-Safi

Keyword(s):

Blood Pressure ◽

Heart Rate ◽

Statistical Analysis ◽

Family History ◽

Smoking Habit ◽

Cardiovascular Disorders ◽

Adult Males ◽

History Of ◽

Family History Of Hypertension ◽

Males And Females

Background: Smoking is a risk factor for cardiovascular, coronary artery and thromboembolic disorders. There is overwhelming evidence supporting the association of cigarette smoking and the development of cardiovascular and thromboembolic events particularly in high risk populations. Aim: The aim of this investigation was to explore the correlation of smoking habit with blood pressure and heart rate values through a randomized cross-sectional epidemiological study in Jordan. Settings and design: This study was performed during the period of February–June 2004. The sample of this investigation included healthy adult males and females from various regions of Jordan. Most of the selected sample included Jordanian university students. Patients with hypertension or cardiovascular disorders were excluded. Methods: Selected individuals of the sample were interviewed by well-trained senior pharmacy students. They were asked initially if they have hypertension or other cardiovascular disorders and if the answer was negative, further questions were asked followed by measurement of the blood pressure and heart rate. Demographic data such as age, sex, nationality, place of residence, occupation and level of education were also recorded. Smokers (for ≥ 6 months) were asked to report how many cigarettes per day they smoke. For each individual of the sample, the systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate were measured three times with 10–15 min intervals in the sitting position and at the resting state. The arterial blood pressure (ABP) was calculated from the measured SBP and DBP. The mean values were distributed according to sex and smoking habit. Statistical analysis: The student unpaired t-test was used for statistical analysis. Results were considered statistically significant when the p value was less than 0.05. Results and conclusion: A total of 14,310 adult males (7400) and females (6910) were selected in various regions of Jordan. The frequencies of smokers and non-smokers in the sample were 3832 (26.8%) and 10478 (73.2%), respectively. Smoker males and females had significantly higher SBP, DBP, ABP values than non-smokers. However, smoking had statistically non-significant effects on heart rate in females while heart rate values were significantly higher in male smokers than in non-smokers. Smoker or non-smoker adults with a positive family history of hypertension had significantly higher blood pressure and heart rate values than those with a negative family history of hypertension. In conclusion, smokers have higher blood pressure than non-smokers.

Download Full-text