Sex and family history of cardiovascular disease influence heart rate variability during stress among healthy adults

Abstract Background Cardiovascular disease is one of the leading causes of death globally with hypertension being a primary cause of premature death from this disease process. Individuals with a family history of cardiovascular disease and hypertension are at a greater risk for developing the same sequela. Autonomic cardiac control is important in the level of cardiac function. One intervention that is effective in improving cardiovascular function is heart rate variability biofeedback training. The purpose of our study was to determine the effectiveness of heart rate biofeedback training on HRV and blood pressure in individuals with a family history of cardiovascular disease. Methods Thirty-four participants (76.5% female, 22.7 ± 4.3 years) completed a baseline assessment and training using an established short-term HRV protocol followed by two weeks of at-home paced breathing employing a smartphone application. The participants were then reassessed in a biofeedback clinic. Results The participants physiological measures showed a significant increase in means between pre and post intervention of SDNN (t (32) = 2.177, p =.037) and TP, (t (32) = 2.327 p = .026). Correlation noted a medium effect on diastolic blood pressure and high frequency heart rate variability, F, r = .41, n =33, p < .05. A multiple regression with all predictor variables in the model found no significance with diastolic and systolic blood pressure. Conclusions The findings from this pilot study demonstrated that a two-week paced breathing intervention may assist in reducing heart rate and diastolic blood pressure while improving heart rate variability.

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A11485 Impact of family history of hypertension and diabetes on heart rate variability in women

Journal of Hypertension ◽

10.1097/01.hjh.0000548247.21108.9d ◽

2018 ◽

Vol 36 ◽

pp. e64

Author(s):

Kátia De Angelis ◽

José Robertto Zaffalon Júnior ◽

Fernando dos Santos ◽

Maria Cláudia Irigoyen ◽

Katia De Angelis

Keyword(s):

Heart Rate ◽

Heart Rate Variability ◽

Family History ◽

History Of ◽

Family History Of Hypertension

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A Possible Early Alteration of Autonomic Activity Assessed by Heart Rate Variability in Saudi Offspring of Type 2 Diabetic Patients

Saudi Journal of Internal Medicine ◽

10.32790/sjim.2011.1.2.4 ◽

2011 ◽

Vol 1 (2) ◽

pp. 17-23

Author(s):

Daad H. Akbar ◽

Maha A. Hegazi ◽

Hanan A. Al Kadi ◽

Maimona M. Ahmad

Keyword(s):

Diabetes Mellitus ◽

Insulin Resistance ◽

Type 2 Diabetes ◽

Heart Rate ◽

Heart Rate Variability ◽

Type 2 Diabetes Mellitus ◽

Family History ◽

Family History Of Diabetes ◽

History Of

Background and Objectives: To evaluate cardiac autonomic function in non-diabetic offspring of Type 2 diabetes mellitus patients through assessment of heart rate variability. Autonomic dysfunction was reported in glucose tolerant on insulin-resistant offspring of Type 2 diabetes mellitus subjects. No data is available on cardiac autonomic dysfunction in Saudi offspring of Type 2 diabetes mellitus. Subject and Methods: Ninety-seven subjects with family history and 30 subjects with no family history of diabetes mellitus as a control group were studied. Anthropometric and biochemical characteristics (fasting blood glucose, lipids, and insulin resistance) were measured. Heart rate variability parameters were recorded. Results: No significant differences in the anthropometric, biochemical or heart rate variability parameters between the group with positive family history of diabetes mellitus and the control group. Subjects with positive family history of diabetes mellitus were split into 2 groups as per the presence or absence of insulin resistance. Insignificantly, an increased sympathetic tone was seen in Type 2 diabetes mellitus offspring with insulin resistance as compared to those without it. Body mass index, waist circumference, waist to hip ratio, total cholesterol, triglyceride, and fasting insulin and fasting blood glucose were also significantly higher in the insulin resistance group. Conclusion: There was a high prevalence of insulin resistance among the young subjects with positive family history of diabetes. Thus, had an increased sympathetic activity compared to those who were insulin sensitive. This study confirms the early autonomic dysfunction in offspring of Type 2 diabetes mellitus subjects previously reported in other non-Saudi populations.

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A Possible Early Alteration of Autonomic Activity Assessed by Heart Rate Variability in Saudi Offspring of Type 2 Diabetic Patients

Saudi Journal of Internal Medicine ◽

10.32790/sjim.1.2.4 ◽

2011 ◽

Vol 1 (2) ◽

pp. 17-23

Author(s):

Daad H. Akbar ◽

Maha A. Hegazi ◽

Hanan A. Al Kadi ◽

Maimona M. Ahmad

Keyword(s):

Diabetes Mellitus ◽

Insulin Resistance ◽

Type 2 Diabetes ◽

Heart Rate ◽

Heart Rate Variability ◽

Type 2 Diabetes Mellitus ◽

Family History ◽

Family History Of Diabetes ◽

History Of

Background and Objectives: To evaluate cardiac autonomic function in non-diabetic offspring of Type 2 diabetes mellitus patients through assessment of heart rate variability. Autonomic dysfunction was reported in glucose tolerant on insulin-resistant offspring of Type 2 diabetes mellitus subjects. No data is available on cardiac autonomic dysfunction in Saudi offspring of Type 2 diabetes mellitus. Subject and Methods: Ninety-seven subjects with family history and 30 subjects with no family history of diabetes mellitus as a control group were studied. Anthropometric and biochemical characteristics (fasting blood glucose, lipids, and insulin resistance) were measured. Heart rate variability parameters were recorded. Results: No significant differences in the anthropometric, biochemical or heart rate variability parameters between the group with positive family history of diabetes mellitus and the control group. Subjects with positive family history of diabetes mellitus were split into 2 groups as per the presence or absence of insulin resistance. Insignificantly, an increased sympathetic tone was seen in Type 2 diabetes mellitus offspring with insulin resistance as compared to those without it. Body mass index, waist circumference, waist to hip ratio, total cholesterol, triglyceride, and fasting insulin and fasting blood glucose were also significantly higher in the insulin resistance group. Conclusion: There was a high prevalence of insulin resistance among the young subjects with positive family history of diabetes. Thus, had an increased sympathetic activity compared to those who were insulin sensitive. This study confirms the early autonomic dysfunction in offspring of Type 2 diabetes mellitus subjects previously reported in other non-Saudi populations.

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HEART RATE VARIABILITY IN YOUNG NORMOTENSIVES WITH A FAMILY HISTORY OF HYPERTENSION

Journal of Hypertension ◽

10.1097/00004872-200006001-00473 ◽

2000 ◽

Vol 18 ◽

pp. S135-S136

Author(s):

K. Kawecka-Jaszcz ◽

K. Stolarz ◽

T. Grodzicki ◽

B. Wizner ◽

W. Lubaszewski ◽

...

Keyword(s):

Heart Rate ◽

Heart Rate Variability ◽

Family History ◽

History Of ◽

Family History Of Hypertension

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Heart Rate Variability(HRV) in Normotensive Subjects with Family History of Hypertension

International Journal of Physiology ◽

10.5958/2320-608x.2016.00022.6 ◽

2016 ◽

Vol 4 (1) ◽

pp. 110

Author(s):

Mohammed Farhan Ahmed ◽

K Indira ◽

Ch N Rajkumari

Keyword(s):

Heart Rate ◽

Heart Rate Variability ◽

Family History ◽

History Of ◽

Family History Of Hypertension ◽

Normotensive Subjects

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Cardiovascular alterations and autonomic imbalance in an experimental model of depression

AJP Regulatory Integrative and Comparative Physiology ◽

10.1152/ajpregu.00614.2001 ◽

2002 ◽

Vol 282 (5) ◽

pp. R1333-R1341 ◽

Cited By ~ 142

Author(s):

Angela J. Grippo ◽

Julia A. Moffitt ◽

Alan Kim Johnson

Keyword(s):

Cardiovascular Disease ◽

Heart Rate ◽

Heart Rate Variability ◽

Essential Feature ◽

Chronic Mild Stress ◽

Mild Stress ◽

Sprague Dawley ◽

Air Jet ◽

Autonomic Blockade ◽

History Of

Depressed patients with and without a history of cardiovascular pathology display signs, such as elevated heart rate, decreased heart rate variability, and increased physiological reactivity to environmental stressors, which may indicate a predisposition to cardiovascular disease. The specific physiological mechanisms associating depression with such altered cardiovascular parameters are presently unclear. The current study investigated cardiovascular regulation in the chronic mild stress rodent model of depression and examined the specific autonomic nervous system mechanisms underlying the responses. Sprague-Dawley rats exposed to a series of mild, unpredictable stressors over 4 wk displayed anhedonia (an essential feature of human depression), along with elevated resting heart rate, decreased heart rate variability, and exaggerated pressor and heart rate responses to air jet stress. Results obtained from experiments studying autonomic blockade suggest that cardiovascular alterations in the chronic mild stress model are mediated by elevated sympathetic tone to the heart. The present findings have implications for the study of pathophysiological links between affective disorders and cardiovascular disease.

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