scholarly journals PS1550 ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION CAN OVERCOME THE POOR OUTCOME OF ADULT PH(+) ACUTE LYMPHOBLASTIC LEUKEMIA -- ON BEHALF OF TAIWAN SOCIETY OF BLOOD AND MARROW TRANSPLANTATION

HemaSphere ◽  
2019 ◽  
Vol 3 (S1) ◽  
pp. 715
Author(s):  
T.-D. Tan ◽  
J.-L. Tang ◽  
M. Yao ◽  
J.-P. Gau ◽  
P.-N. Wang ◽  
...  
JBMTCT ◽  
2021 ◽  
Vol 4 (1) ◽  
pp. 61-71
Author(s):  
Sociedade Brasileira de TMO SBTMO ◽  
Marco Aurelio Salvino ◽  
Maura Valerio Ikoma ◽  
Rodolfo Soares ◽  
Andreza Ribeiro ◽  
...  

THE BRAZILIAN SOCIETY FOR BLOOD AND MARROW TRANSPLANTATION (SBTMO) PRESENTS THE BRAZILIAN GUIDELINES ON HEMATOPOIETIC STEM CELL TRANSPLANTATION


Chemotherapy ◽  
2018 ◽  
Vol 63 (4) ◽  
pp. 220-224 ◽  
Author(s):  
Maria Cristina Pirosa ◽  
Salvatore Leotta ◽  
Alessandra Cupri ◽  
Stefania Stella ◽  
Enrica Antonia Martino ◽  
...  

Ph’+ acute lymphoblastic leukemia (Ph’+-ALL) is an oncohematologic disorder for which allogeneic bone marrow transplantation still offers the only chance of cure. However, relapse is the main reason for treatment failure, also after hematopoietic stem cell transplantation (HSCT). New drugs, such as third generation tyrosine kinase inhibitors (TKIs) and monoclonal antibodies, have expanded the therapeutic landscape, especially in patients who relapsed before HSCT. Very few reports, up to now, have described the use of both classes of these new agents in combination with donor lymphocyte infusions (DLI) in the setting of patients who relapsed after HSCT. We report on a young patient affected by Ph’+-ALL, who relapsed after the second HSCT and who reached molecular remission and long-term disease control by treatment with the anti-CD22 monoclonal antibody inotuzumab ozogamicin, DLI, and the 3rd generation TKI ponatinib.


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