Continuous venovenous hemofiltration with or without extracorporeal membrane oxygenation in children*

2007 ◽  
Vol PAP ◽  
Author(s):  
Ihab Sakr Shaheen ◽  
Ben Harvey ◽  
Alan R. Watson ◽  
Hitesh C. Pandya ◽  
Anton Mayer ◽  
...  
Keyword(s):  
Extracorporeal Membrane Oxygenation ◽  
Continuous Venovenous Hemofiltration ◽  
Membrane Oxygenation

Treatment of hyperammonemia using in-line renal replacement and hyperosmolar therapies within an extracorporeal membrane oxygenation circuit

Perfusion ◽  
2021 ◽  
pp. 026765912110359
Author(s):  
Alison Grazioli ◽  
Jamie E Podell ◽  
Aldo Iacono ◽  
Alexander Sasha Krupnik ◽  
Ronson J Madathil ◽  
...  
Keyword(s):  
Extracorporeal Membrane Oxygenation ◽  
Cerebral Edema ◽  
Urea Cycle ◽  
Rare Complication ◽  
Volume Of Distribution ◽  
Intermittent Hemodialysis ◽  
Treatment Goals ◽  
Continuous Venovenous Hemofiltration ◽  
Small Molecular Weight ◽  
Membrane Oxygenation

After orthotopic lung transplantation, hyperammonemia can be a rare complication secondary to infection by organisms that produce urease or inhibit the urea cycle. This can cause neurotoxicity, cerebral edema, and seizures. Ammonia is unique in that it has a large volume of distribution. However, it is also readily dialyzable given its small molecular weight. As such, removal of ammonia requires renal replacement modalities that can both rapidly remove ammonia from the plasma space and allow for continuous removal to prevent rebound accumulation from intracellular stores. Prevention of iatrogenic osmotic lowering in this setting is required to prevent worsening of cerebral edema. Herein, we describe use of sequential in-line renal replacement therapy using both intermittent hemodialysis and continuous venovenous hemofiltration within an extracorporeal membrane oxygenation circuit in conjunction with higher sodium dialysate and 7.5% hypertonic saline to achieve these treatment goals.

Extracorporeal membrane oxygenation support after heart- or lungtransplantation

2011 ◽  
Vol 59 (S 01) ◽  
Author(s):  
A Mühle ◽  
G Färber ◽  
T Doenst ◽  
M Barten ◽  
J Garbade ◽  
...  
Keyword(s):  
Extracorporeal Membrane Oxygenation ◽  
Membrane Oxygenation
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