551 The Impact of Nasal Polyposis on Quality of Life Using the Eq-5d Health Profile

Abstract BACKGROUND: To date, no disease-specific tool is available to assess the impact of Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) on Health Related Quality of Life (HRQoL). Therefore, the purpose of this study was to develop and validate a questionnaire specifically designed to this aim: the Nasal Polyposis Quality of Life questionnaire –NPQ.METHODS: According to the current guidelines, the development and validation of the NPQ occurred in two separate steps involving different groups of patients.RESULTS: In the development process of NPQ an initial list of items of 40 items was given to 60 patients with CRSwNP; the 27 most significant items were selected and converted into questions. The validation procedure involved 107 patients (mean age 52.9±12.4). NPQ revealed a five-dimensional structure and high levels of internal consistency (Cronbach's alpha 0.95). Convergent validity (Spearman’ coefficient r=0.75; p< 0.01), discriminant validity (sensitivity to VAS score), reliability in a sample of patients with a stable health status (Interclass Coefficient 0.882) were satisfactory. Responsiveness to clinical changes was accomplished. The minimal important difference was 7. CONCLUSIONS: NPQ is the first questionnaire for the assessment of HRQoL in CRSwNP. Our results provide that the new tool is valid, reliable, and sensitive to individual changes.

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The Impact of Atopy, Sinus Opacification, and Nasal Patency on Quality of Life in Patients with Severe Nasal Polyposis

Otolaryngology ◽

10.1016/j.otohns.2005.10.061 ◽

2006 ◽

Vol 134 (4) ◽

pp. 609-612 ◽

Cited By ~ 22

Author(s):

Isam Alobid ◽

Pedro Benítez ◽

Antonio Valero ◽

Joan Berenguer ◽

Manuel Bernal-Sprekelsen ◽

...

Keyword(s):

Quality Of Life ◽

Nasal Polyposis ◽

Nasal Patency ◽

The Impact

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Nasal polyposis in France: impact on sleep and quality of life

The Journal of Laryngology & Otology ◽

10.1258/0022215054352108 ◽

2005 ◽

Vol 119 (7) ◽

pp. 543-549 ◽

Cited By ~ 30

Author(s):

Elie Serrano ◽

Françoise Neukirch ◽

Céline Pribil ◽

Roger Jankowski ◽

Jean-Michel Klossek ◽

...

Keyword(s):

Quality Of Life ◽

Sleep Disorders ◽

Nasal Polyposis ◽

Negative Impact ◽

Two Dimensions ◽

Control Group ◽

Validated Questionnaire ◽

Sf 36 ◽

The Impact

The prevalence of nasal polyposis (NP) in France (2.11 per cent) and its epidemiology (detection, medical management, patients' characteristics, risk factors, associated diseases, etc.) were determined in a population-based, cross-sectional, case–control study of 10 033 adults carried out in 2002. The impact of this disease on daily living was also studied, by the analysis of potential sleep disorders (validated questionnaire) and quality of life (QOL, SF-36 questionnaire) of NP patients, in a comparison with a matched-control group of individuals without NP.A quarter of NP patients (24.6 per cent) reported a feeling of general discomfort due to their nasal condition, during the day as well as the night in most of these cases (61.2 per cent). Compared with controls, NP patients have a two-fold higher risk of suffering sleep disturbance (odds ratio [OR]: 2.25, 95 per cent confidence interval [95% CI] [1.54; 3.29]). Snoring was reported by 50.5 per cent of NP patients vs 35.7 per cent of controls (p < 0.001). All scores from the SF-36 questionnaire demonstrated a significant negative impact of NP on the different aspects of QOL.The current study underlines the negative impact of NP on QOL and sleep, two dimensions that are rarely considered in its pathology. In addition to the discomfort and lowered QOL experienced by patients with this disease, a significant increase in sleep disorders was shown, suggesting a risk of suffering further chronic diseases and complications.

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The impact of elagolix on quality of life in women with endometriosis-associated pain: results from two randomized, placebo-controlled studies using the endometriosis health profile questionnaire

Fertility and Sterility ◽

10.1016/j.fertnstert.2016.07.271 ◽

2016 ◽

Vol 106 (3) ◽

pp. e93 ◽

Cited By ~ 1

Author(s):

H.S. Taylor ◽

E. Surrey ◽

A.M. Soliman ◽

J. Castelli-Haley ◽

J.P. Rowan ◽

...

Keyword(s):

Quality Of Life ◽

Health Profile ◽

The Impact

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The impact of asthma and aspirin sensitivity on quality of life of patients with nasal polyposis

Quality of Life Research ◽

10.1007/s11136-004-1597-x ◽

2005 ◽

Vol 14 (3) ◽

pp. 789-793 ◽

Cited By ~ 35

Author(s):

Isam Alobid ◽

Pedro Ben�tez ◽

Manuel Bernal-Sprekelsen ◽

Jos� Mar�a Guilemany ◽

Cesar Picado ◽

...

Keyword(s):

Quality Of Life ◽

Nasal Polyposis ◽

Aspirin Sensitivity ◽

The Impact

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Self-Compassion and Quality of Life in Adults Who Stutter

American Journal of Speech-Language Pathology ◽

10.1044/2020_ajslp-20-00055 ◽

2020 ◽

Vol 29 (4) ◽

pp. 2097-2108

Author(s):

Robyn L. Croft ◽

Courtney T. Byrd

Keyword(s):

Quality Of Life ◽

Social Connectedness ◽

The Self ◽

Future Research ◽

Self Compassion ◽

Adults Who Stutter ◽

And Gender ◽

Relationship Of ◽

The Impact

Purpose The purpose of this study was to identify levels of self-compassion in adults who do and do not stutter and to determine whether self-compassion predicts the impact of stuttering on quality of life in adults who stutter. Method Participants included 140 adults who do and do not stutter matched for age and gender. All participants completed the Self-Compassion Scale. Adults who stutter also completed the Overall Assessment of the Speaker's Experience of Stuttering. Data were analyzed for self-compassion differences between and within adults who do and do not stutter and to predict self-compassion on quality of life in adults who stutter. Results Adults who do and do not stutter exhibited no significant differences in total self-compassion, regardless of participant gender. A simple linear regression of the total self-compassion score and total Overall Assessment of the Speaker's Experience of Stuttering score showed a significant, negative linear relationship of self-compassion predicting the impact of stuttering on quality of life. Conclusions Data suggest that higher levels of self-kindness, mindfulness, and social connectedness (i.e., self-compassion) are related to reduced negative reactions to stuttering, an increased participation in daily communication situations, and an improved overall quality of life. Future research should replicate current findings and identify moderators of the self-compassion–quality of life relationship.

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