Circ_0074027 contributes to the progression of non-small cell lung cancer via microRNA-362-3p/clathrin heavy chain axis

2020 ◽  
Vol 32 (1) ◽  
pp. 1-10
Author(s):  
Zhenzhu Jiang ◽  
Jing Yin ◽  
Guangyao Peng ◽  
Xiaoping Long
2020 ◽  
Author(s):  
Shahan Mamoor

Non-small cell lung cancer (NSCLC) is the leading cause of cancer death in the United States (1). We mined published microarray data (2, 3, 4) to identify differentially expressed genes in NSCLC. We found that the gene encoding the inter-α-trypsin inhibitor heavy chain family member 5, ITIH5, was among those whose expression was most different in human NSCLC tumors as compared to the lung. ITIH5 expression levels were significantly decreased in NSCLC tumors as compared to the lung, and lower expression of ITIH5 in patient tumors was significantly associated with worse overall survival. ITIH5 may be important for initiation or progression of non-small cell lung cancer in humans.


2016 ◽  
Vol 22 ◽  
pp. 176
Author(s):  
Genevieve Streb ◽  
Narjust Duma ◽  
Natasha Piracha ◽  
Sejal Kothadia ◽  
Komal Patel ◽  
...  

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