Clinical Course of Neuroendocrine Tumors With Different Origins (the Pancreas, Gastrointestinal Tract, and Lung)

2012 ◽  
Vol 35 (6) ◽  
pp. 549-556 ◽  
Author(s):  
Su-Jung Kim ◽  
Jin Won Kim ◽  
Do-Youn Oh ◽  
Sae-Won Han ◽  
Se-Hoon Lee ◽  
...  
Keyword(s):  
Gastrointestinal Tract ◽  
Neuroendocrine Tumors ◽  
Clinical Course ◽  
Different Origins

Distinct clinical course of neuroendocrine tumors presenting ectopic ACTH tissue expression and secretion

2020 ◽  
Author(s):  
Michalina Oszywa ◽  
Martyna Borowczyk ◽  
Ewelina Szczepanek-Parulska ◽  
Paweł Gut ◽  
Marek Ruchała
Keyword(s):  
Neuroendocrine Tumors ◽  
Clinical Course ◽  
Tissue Expression ◽  
Ectopic Acth

scholarly journals CD117 (c-kit), CD34, and DOG-1 Immunoreactivity in Neuroendocrine Tumors of Gastrointestinal Tract

2012 ◽  
Vol 138 (suppl 1) ◽  
pp. A239-A239
Author(s):  
Oleksandr Yergiyev ◽  
Jan F. Silverman ◽  
Yulin Liu
Keyword(s):  
Gastrointestinal Tract ◽  
Neuroendocrine Tumors

IL-2 −330 T/G SNP and serum values—potential new tumor markers in neuroendocrine tumors of the gastrointestinal tract and pancreas (GEP-NETs)

2010 ◽  
Vol 88 (4) ◽  
pp. 423-429 ◽  
Author(s):  
Maja Cigrovski Berković ◽  
Mladen Jokić ◽  
Jasminka Marout ◽  
Senka Radošević ◽  
Vanja Zjačić-Rotkvić ◽  
...  
Keyword(s):  
Gastrointestinal Tract ◽  
Tumor Markers ◽  
Neuroendocrine Tumors

scholarly journals Generalized tetanus in an 11-year-old boy: A case report

2021 ◽  
Vol 11 (1) ◽  
pp. 69-75
Author(s):  
Artem A. Kozlov ◽  
Irina V. Shevchuk ◽  
Aleksei E. Zavialov ◽  
Anatoly N. Emelyanov
Keyword(s):  
Case Report ◽  
Respiratory Failure ◽  
Gastrointestinal Tract ◽  
Pain Relief ◽  
Antibiotic Therapy ◽  
Clinical Course ◽  
Treatment Strategies ◽  
Adequate Pain Relief ◽  
Choice Of Treatment ◽  
Severe Tetanus

The study presents a case report of a generalized form of severe tetanus in an unvaccinated 11-year-old child. Pain and convulsive syndromes, respiratory failure, and damage to the gastrointestinal tract prevailed in the acute period. Antibiotic therapy, anti-tetanus serum, adequate pain relief, and anticonvulsant therapy were the leading treatments of the child. Moreover, the paper discusses literature data on the options for the clinical course and choice of treatment strategies. The lack of planned vaccination in children is unsafe.

Current aspects of diagnosis and treatment of patients with neuroendocrine tumors

2021 ◽  
Vol 23 (3) ◽  
pp. 83-92
Author(s):  
Maxim V. Lysanyuk ◽  
Pavel N. Romashchenko ◽  
Nicolay A. Maistrenko
Keyword(s):  
Gastrointestinal Tract ◽  
Neuroendocrine Tumors ◽  
Survival Rates ◽  
Neuron Specific Enolase ◽  
Treatment Method ◽  
Pancreatic Tumors ◽  
Arterial Phase ◽  
Computed Tomographic ◽  
Positron Emission ◽  
Degree Of Malignancy

The article presents modern possibilities and existing problematic aspects of the choice of therapeutic and diagnostic tactics in patients with neuroendocrine tumors of the gastrointestinal tract and pancreas are presented. The asymptomatic course of neuroendocrine tumors of the gastrointestinal tract and pancreas was established in 18.5% and 24.6% of cases, respectively. Carcinoid syndrome was detected in 12.9%. The sensitivity rates of chromogranin A and neuron-specific enolase in the diagnosis of tumors were 54% and 13%, respectively. The levels of cancer-embryonic antigen in G-1/G-2 and G-3 tumors were 5 ng/ml and 8.9 ng/ml, respectively (p 0.001). A pathognomonic sign of neuroendocrine tumors of the small intestine is a mesentery tumor conglomerate, and the sensitivity rates of computed tomography and positron emission tomography with 68Ga to detect this sign were 92.3% and 92.9%, respectively (p 0.05). The computed tomographic density of neuroendocrine pancreatic tumors G-1/G-2 in the arterial phase was 112.1 40.2 HU and that of G-3 tumors was 54.0 10.4 HU (p = 0.025). Surgical treatment was performed in 259 (79.7%) patients. Postoperative complications that developed in localized and locally distributed neuroendocrine tumors of the gastrointestinal tract and of the pancreas were found in 3.5% and 8.8%, and in 58.1% and 40% of the cases, respectively, and those of generalized tumors were noted in 20%. The tumor-specific 5-year survival rates of patients with localized neuroendocrine tumors of the gastrointestinal tract and pancreas were 92.5% and 94.4%, those with locally distributed tumors had 66.8% and 77.8%, and those with generalized tumors had 51.8% and 47.1%, respectively. In patients with generalized tumors, the 5-year survival rates after cytoreduction and removal of the primary tumor were 88.2% and 64.6%, respectively (p = 0.097), and the rate after drug therapy was 28.8% (p 0.001). The prognosis of the 5-year survival of patients is determined by the degree of malignancy and tumor localization, treatment method, and patient age. In general, neuroendocrine tumors are a heterogeneous group of neoplasms that require a multidisciplinary approach to diagnosis and choice of therapeutic strategies.

Neuroendocrine tumor of the periappendicular area of the cecum bottom – a case report

2021 ◽  
Vol 75 (1) ◽  
pp. 68-71
Author(s):  
Lukáš Bača ◽  
Róbert Psár ◽  
Martin Hanousek ◽  
Petr Fojtík
Keyword(s):  
Case Report ◽  
Gastrointestinal Tract ◽  
Neuroendocrine Tumor ◽  
Neuroendocrine Tumors ◽  
Enteroendocrine Cells ◽  
Special Group ◽  
Slow Growing

Neuroendocrine tumors are slow-growing neoplasms, histologically based on enteroendocrine cells. They are tumors with different degrees of differentiation, uncertain bio­logical nature and metastatic ability. Their most common localization is the gastrointestinal tract, with a special group of the neuroendocrine tumors of appendix, which are incidentally found after appendectomy. In case report, we would like to present a case of a patient with neuroendocrine tumors of appendix dia­gnosed by colonoscopy.

scholarly journals P-0139 Xelox Regimen in Treatment of Neuroendocrine Tumors of Gastrointestinal Tract (Preliminary Results)

2012 ◽  
Vol 23 ◽  
pp. iv71
Author(s):  
Alla Markovich ◽  
Vera Gorbunova ◽  
Nadezhda Orel ◽  
Galina Emelyanova
Keyword(s):  
Gastrointestinal Tract ◽  
Neuroendocrine Tumors ◽  
Preliminary Results

scholarly journals The ENETS and AJCC/UICC TNM classifications of the neuroendocrine tumors of the gastrointestinal tract and the pancreas: a statement

2010 ◽  
Vol 456 (6) ◽  
pp. 595-597 ◽  
Author(s):  
Günter Klöppel ◽  
Guido Rindi ◽  
Aurel Perren ◽  
Paul Komminoth ◽  
David S. Klimstra
Keyword(s):  
Gastrointestinal Tract ◽  
Neuroendocrine Tumors

Peritoneal carcinomatosis from small intestinal neuroendocrine tumors: Clinical course and genetic profiling

Surgery ◽  
2014 ◽  
Vol 156 (6) ◽  
pp. 1512-1522 ◽  
Author(s):  
Olov Norlén ◽  
Katarina Edfeldt ◽  
Goran Akerstrom ◽  
Gunnar Westin ◽  
Per Hellman ◽  
...  
Keyword(s):  
Peritoneal Carcinomatosis ◽  
Neuroendocrine Tumors ◽  
Clinical Course ◽  
Genetic Profiling ◽  
Small Intestinal
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