scholarly journals Evaluation of Holmium Laser Enucleation of the Prostate Learning Curves with and without a Structured Training Programme: Erratum

2021 ◽  
Vol 15 (4) ◽  
pp. 240
2020 ◽  
Vol 14 (4) ◽  
pp. 191-199
Author(s):  
Thilo Westhofen ◽  
Philipp Weinhold ◽  
Maurice Kolb ◽  
Christian G. Stief ◽  
Giuseppe Magistro

<b><i>Background/Aims: </i></b>To evaluate perioperative parameters, early functional outcomes, and the safety profile of holmium laser enucleation of the prostate learning curves with and without mentoring. <b><i>Methods: </i></b>The learning curves of 2 surgeons of their first 100 consecutive patients treated with holmium laser enucleation of the prostate were retrospectively analyzed. We analyzed demographic parameters, clinical outcomes, adverse events, and the progress during each learning experience. <b><i>Results:</i></b> The only statistically significant differences between the two learning curves were found for operation time (138.2 ± 60.7 vs. 98.2 ± 37.7 min; p < 0.001) in favor of the supervised approach, the total weight of resected prostatic tissue (81.5 ± 50.5 vs. 65.0 ± 6.7 g; p < 0.001) with more tissue removal by the surgeon without guidance, and the perioperative hemoglobin drop (1.9 ± 1.4 vs. 1.1 ± 1.0 g/dl; p < 0.001) in favor of the learning curve with a training programme. In multivariate logistic regression, the time factor was independently associated with a higher drop in hemoglobin levels (OR 1.015; 95% CI 1.000-1.023; p = 0.001). The improvements of clinical outcomes as determined by International Prostate Symptom Score, quality of life, peak urinary flow rate and postvoid residual volume were comparable. After the first 50 procedures the mean operation time significantly improved from 147 to 107.5 minutes for the learning curve without supervision (p < 0.001), whereas the surgical time was consistent throughout the 100 cases with a mentoring programme. The overall incidence of treatment-related adverse events was significantly higher without the training programme (16 vs. 5%; p = 0.008). <b><i>Conclusions: </i></b>Our study clearly showed the benefits of a structured training programme to overcome the steep learning curve.


2020 ◽  
Vol 104 (11-12) ◽  
pp. 914-922
Author(s):  
Bernd Rosenhammer ◽  
Maximilian Schönhärl ◽  
Roman Mayr ◽  
Marco J. Schnabel ◽  
Maximilian Burger ◽  
...  

<b><i>Introduction:</i></b> While holmium laser enucleation of the prostate (HoLEP) is accepted as safe and efficient, a long learning curve is considered the main reason for its slow adoption in clinical practice. So far, no standardized and easy-to-use parameter has been implemented to measure surgical experience or efficiency which could be useful for training and quality control purposes. The aim of the present study was to evaluate the learning curves of 2 HoLEP beginners and to identify applicable efficiency outcome measures as well as potentially complicating factors in performing HoLEP. <b><i>Patients and Methods:</i></b> A total of 594 patients treated by HoLEP between September 2016 and May 2019 were enrolled. The procedures were initially performed by 1 HoLEP expert (reference surgeon); over time, 2 further surgeons were trained. Baseline characteristics, enucleation weight, morcellation and enucleation time, laser energy usage, and postoperative results were recorded prospectively. The learning curves of the 2 novices were analyzed and compared to the reference surgeon. Logistic regression analyses were performed to identify predictors for postoperative grade ≥2 complications. <b><i>Results:</i></b> Median enucleation ratio and complication rates did not significantly alter along the learning curves. Median enucleation speed and laser energy application of the 2 novices significantly improved with growing experience. Combining these variables, we introduced the “HoLEP efficiency score” (HES) which demonstrated the most appropriate value to reflect the surgical experience and efficiency. The median HES for the reference surgeon was 82.8 min kJ/g. For the 2 novices, a drop from 130 and 124.4 min kJ/g by −57 and −30%, respectively, was observed. Among several tested clinical parameters, the presence of prostate cancer (<i>p</i> = 0.047) and the surgical caseload (<i>p</i> &#x3c; 0.001) influenced the HES. On multivariable logistic regression, American Society of Anesthesiologists score and prostate cancer were independent predictors for grade ≥2 complications (<i>p</i> = 0.002, odds ratio [OR] 2.042 and <i>p</i> = 0.038, OR 1.940). <b><i>Conclusion:</i></b> We introduce the HES as an objective and measurable tool to quantify surgical efficiency. In clinical practice, the HES may find application in training and quality control purposes as well as in comparing surgical modifications and hardware. Patients with prostate cancer seem to be more challenging cases and have a higher risk for complications, and may preferably be treated by experienced surgeons.


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