holmium laser
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2022 ◽  
Vol 509 (2) ◽  
Author(s):  
Võ Văn Chung ◽  
Đỗ Trường Thành
Keyword(s):  

Mục đích: Trong nghiên cứu này chúng tôi áp dụng kỹ thuật bóc nhân phì đại lành tính tuyến tiền liệt nội soi qua đường niệu đạo theo phương pháp 1 khối cải tiến và đánh giá tính an toàn, kết quả sớm của phẫu thuật bóc nhân phì đại lành tính tuyến tiền liệt theo phương pháp bóc nhân một khối. Phương pháp nghiên cứu: chúng tôi nghiên cứu tiến cứu trên 38 bệnh nhân rối loạn tiểu tiện do u phì đại lành tính tuyến tiền liệt, được phẫu thuật bóc nhân phì đại bằng laser Holmium từ tháng 4/2020 đến tháng 8/2020. Kỹ thuật phẫu thuật bóc nhân phì đại 1 khối cải tiến được thực hiện bằng 2 đường rạch ở vị trí 12h và 6h. Trong mổ chúng tôi đánh giá thời gian bóc nhân phì đại, thời gian say nhỏ và lấy bệnh phẩm ra ngoài. Lượng máu mất, các tai biến trong mổ. Các thông số sau mổ bao gồm: thời gian đặt ống thông niệu đạo, thời gian nằm viện. Tình trạng tiểu tiện sau mổ. Các biến chứng sau mổ được đánh giá theo phân độ của Clavien–Dindo. Bệnh nhân được đánh giá theo dõi ở thời điểm 3 tháng sau mổ. Kết quả: Có 38 TH thực hiện HoLEP. Tuổi trung bình là 73.7 ± 10.4,. có 52.6% bệnh nhân có bệnh lý nền kèm theo. 100% bệnh nhân nhập viện với điểm IPSS ở mức độ nặng ≥ 20 điểm (trung bình trước mổ là 28.95)  và 84.21% bệnh nhân đánh giá chất lượng cuộc sống ở mức khổ sở, không chịu được với điểm QoL ≥ 5 điểm. Thể tích TTL đo được trên siêu âm trung bình là 75.97 ± 27.65 ml. Thời gian phẫu thuật trung bình là 96.84 ± 11.47. Thời gian bóc u trung bình là 66.21 ± 10.81.Mức chênh lệch HGB trước và sau mổ không đáng kể 1.09 ± 0.78 g/dL, tuy nhiên biến chứng sau mổ cao nhất là truyền máu sau mổ với 10.53% do đa số các trường hợp này có mức HGB trước mổ thấp. Thang điểm quốc tế về triệu chứng TTL (IPSS) cải thiện sau mổ 1, 3, 6 tháng xuống lần lượt là 6.16, 4.39, 3.61. 100% bệnh nhân đánh giá chất lượng cuộc sống sau 6 tháng phẫu thuật ở mức tốt với điểm QoL trung bình là 1.24.  Kết luận: Phẫu thuật bóc nhân phì đại lành tính TTL HoLEP ở bệnh nhân U phì đại lành tính TTL là phẫu thuật an toàn dễ thực hiện và có hiệu quả với mọi kích thước của u phì đại lành tính tuyến tiền liệt.


2022 ◽  
Vol 48 (1) ◽  
pp. 200-201
Author(s):  
Antonio Andrea Grosso ◽  
Fabrizio Di Maida ◽  
Andrea Mari ◽  
Samuele Nardoni ◽  
Agostino Tuccio ◽  
...  

Photonics ◽  
2021 ◽  
Vol 9 (1) ◽  
pp. 20
Author(s):  
Mariya S. Kopyeva ◽  
Serafima A. Filatova ◽  
Vladimir A. Kamynin ◽  
Anton I. Trikshev ◽  
Elizaveta I. Kozlikina ◽  
...  

We present the results on the interaction of an all-fiber Holmium-doped laser CW radiation at a wavelength of 2100 nm with soft tissues and compare it with the other results obtained by the most used solid-state laser systems. Ex-vivo single spot experiments were carried out on the porcine longissimus muscles by varying the laser impact parameters in a wide range (average output power 0.3, 0.5 and 1.1 W; exposure time 5, 30 and 60 s). Evaluation of the laser radiation exposure was carried out by the size of coagulation and ablation zones on the morphological study. Exposure to a power of 0.3 W (1.5–18 J of applied energy) caused only reversible changes in the tissues. The highest applied energy of 66 J for 1.1 W and a 60-s exposure resulted in a maximum ablation depth of approximately 1.2 mm, with an ablation efficiency of 35%. We have shown that it is not necessary to use high powers of CW radiation, such as 5–10 W in the solid-state systems to provide the destructive effects. Similar results can be achieved at lower powers using the simple all-fiber Holmium laser based on the standard single-mode fiber, which could provide higher power densities and be more convenient to manufacture and use. The obtained results may be valuable as an additional experimental point in the field of existing results, which in the future will allow one to create a simple optimal laser system for medical purposes.


2021 ◽  
Author(s):  
Alba Sierra del Rio ◽  
Eugenio Ventimiglia ◽  
Mariela Corrales ◽  
Olivier TRAXER
Keyword(s):  

2021 ◽  
Vol 93 (4) ◽  
pp. 412-417
Author(s):  
Güçlü Gürlen ◽  
Kadir Karkin

Aim: The aim of our study is to examine the learning curve of HoLEP and to discuss our results in the light of the literature. Methods: 100 patients who had LUTS resistant to medical treatment and complicated BPH to whom HoLEP procedure had been administered regardless of the size of the prostate in the last 1 year were analysed retrospectively. To evaluate the learning curve, the patients were classified into 4 main groups of 25 consecutively operated patients beginning from the first case. The 4 main groups were divided into 2 subgroups including patients who had prostate volume below or above 80 grams. Results: The mean age of the 100 patients who had HoLEP was 64.5 years. The mean prostate volume was 99.1 cc (45-281 cc). When those with prostate smaller than 80 g are examined, Enucleation efficiency was 0.76 g/min (0.46-0.97 g/min) and Morcellation efficiency was 3.07 g/min (3.34-4 g/min). When those with prostates larger than 80 g are examined, Enucleation efficiency was 0.89 g/min (0.66-1.04 g/min) and Morcellation efficiency was 4.01 g/min (3.93-4.25 g/min). These two parameters were statistically and significantly different in all the 4 groups (p < 0.05). Conclusions: HoLEP still has a steep learning curve. It is necessary to reach the number of cases of 25-50 to reach fundamental experience.


2021 ◽  
Author(s):  
Song Guo ◽  
Kai Zhu ◽  
Fu Qiang ◽  
Meiju Yan ◽  
Donghua Hang

Abstract Background Oxidative stress has been considered a critical mediator in the pathogenesis of lumbar disc degeneration, which can lead to the severe lower back pain. Inhibition of the excessive oxidative stress has become a therapeutic target for controlling discogenic lower back pain. Recently, more studies have shown that holmium laser can effectively suppress oxidative stress. This work aims to study the clinical outcomes of percutaneous full-endoscopy spine surgery combined with holmium laser for treating symptomatic lumbar disc degeneration (IDD). Methods We designed and conducted a retrospective study on the patients with lumbar disc herniation who had been treated by percutaneous full-endoscopy spine surgery at Shanghai General Hospital from June 2018 to March 2020. The patients were divided into group A (holmium laser treatment group) and group B (Elliquence radiofrequency group) according to the medical record. Operation time and hospitalization time of both groups were recorded and compared. Additionally, VAS scores and ODI scores were used to evaluate the lower back pain, lower extremity radiation pain and quality of life before and 3 days, 6 months, and 12 months after surgery. Results Forty-five patients were included in group A while the other 55 patients were included in group B. Operation time of group A was significantly shorter than that of group B (40.60±5.59 minutes vs. 50.80±3.19 minutes). VAS scores of lower back pain and lower extremity radiation pain at postoperative 3 days, 6 months, and 12 months were significantly lower than those before surgery in both groups. The postoperative lower back pain VAS scores of group A were significantly lower than those of group B, while the postoperative lower extremity radiation pain VAS scores had no significant difference between both groups. The ODI scores of both groups at postoperative 3 days, 6 months, and 12 months were significantly lower than those before surgery. Conclusions These findings confirmed that application of holmium laser can significantly improve the clinical outcomes in percutaneous full-endoscopy spine surgery.


2021 ◽  
pp. 205141582110624
Author(s):  
Mahmoud Abuelnaga ◽  
Ala’a Sharaf ◽  
James Armitage

Introduction: Since Holmium laser enucleation of the prostate (HoLEP) was introduced in the 1990s as an endoscopic deobstructing modality for benign prostatic hyperplasia (BPH), several reports have concluded that HoLEP has compared favourably to transurethral resection of prostate (TURP) in relieving Bladder Outlet Obstruction (BOO). However, there has been no consensus regarding the efficacy of surgical management of men with Detrusor Underactivity (DU) and BOO. Methods: We performed a literature search of PubMed, Google Scholar, Scopus, and Web of Science databases. All studies that provided data on the effectiveness of HoLEP in men with BOO and DU were assessed. Data collected included the number of patients, median follow-up, International Prostate Symptom Score (IPSS), Qmax, post-void residual (PVR) and catheter dependency pre- and post-intervention. Results: Nine studies were identified in the literature with a follow-up range between 6 and 60 months. Only one prospective study was identified where investigators performed urodynamic studies (UDSs) before and after the intervention. In addition to a significant improvement of voiding parameters, they reported partial recovery of detrusor muscle contractility in approximately 80% of patients. Furthermore, all other studies reported an improvement in all outcome parameters and proved the efficacy of HoLEP in patients with DU and BOO. Conclusion: The current literature underpins the efficacy of HoLEP in patients with impaired bladder contractility. However, current research is limited and the majority of the published data are retrospective in nature. Therefore, more well-conducted prospective randomised studies are needed to reinforce high-level evidence for this hypothesis. Level of evidence: Not applicable.


2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Hu Li ◽  
Zhijun Chen ◽  
Dezhi Kong ◽  
Zhiqiang Huang ◽  
Ningning Wang

This study was to investigate the application value of ultrasound images optimized by support vector machine (SVM) algorithm in the efficacy analysis of holmium laser lithotripsy in the treatment of urinary calculi. 92 patients for treatment of UC were selected as research subjects, with 46 cases in each group. The control group received pneumatic lithotripsy for diagnosis and treatment. The observation group received holmium laser lithotripsy for calculus treatment. The perimeter and area of the defect and the length and width of the external distance of the most effective area of the defect were used as classification features, and a classifier based on SVM was constructed and applied to it. After treatment, the success rate, operation duration, stone clearance time, and hospital stay of the two groups were comprehensively evaluated. The results showed that the success rate of the observation group adopting holmium laser lithotripsy was 100%. The duration of operation in the observation group was (29.7 ± 7.65) min, and the time to clear calculus was (6.99 ± 5.29) days. The length of hospital stay was (3.67 ± 2.9) days. The probability of complications in the observation group was 3.11%. The observation group was superior to the control group in all surgical indicators (95%, 40.7 ± 8.36 minutes, 14.1 ± 7.21 days, and 5.12 ± 3.72 days), with considerable differences between groups ( P < 0.05 ). The strong support structure similarity information improved the detection and diagnostic analysis ability of ultrasonic images. In conclusion, after ultrasound image evaluation based on SVM algorithm, the adoption of holmium laser lithotripsy can effectively improve the success rate of patients with urinary system disease, which was worthy of clinical adoption and promotion.


2021 ◽  
Vol 22 (12) ◽  
Author(s):  
Naveen K. Reddy ◽  
Abhijit P. Patil ◽  
Gopal R. Tak ◽  
Darshit Shah ◽  
Abhishek G. Singh ◽  
...  

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