Nevus Sebaceous of Jadassohn With Eight Secondary Tumors of Follicular, Sebaceous, and Sweat Gland Differentiation

Nevus sebaceous (NS) is a benign tumor with the potential to develop secondary benign and malignant neoplasms. It is a rare phenomenon to develop 2 or more skin tumors in a single NS lesion. We report a case of multiple secondary tumors, such as sebaceoma, sebaceous carcinoma, syringocystadenoma papilliferum, and trichoblastoma, in a single NS lesion.

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Two cases of nevus sebaceous accompanying secondary tumors with βKlotho expression

The Journal of Dermatology ◽

10.1111/1346-8138.12371 ◽

2014 ◽

Vol 41 (2) ◽

pp. 171-172 ◽

Cited By ~ 1

Author(s):

Kozo Nakai ◽

Kozo Yoneda ◽

Reiji Haba ◽

Yoshio Kushida ◽

Naomi Katsuki ◽

...

Keyword(s):

Secondary Tumors ◽

Nevus Sebaceous

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Secondary Tumor Arising in a Nevus Sebaceous

Serbian Journal of Dermatology and Venerology ◽

10.2478/sjdv-2020-0018 ◽

2020 ◽

Vol 12 (4) ◽

pp. 147-151

Author(s):

Biljana Jeremić Gajinov ◽

Sonja Prćić ◽

Milana Ivkov Simić ◽

Nada Vučković ◽

Milan Matić ◽

...

Keyword(s):

Final Diagnosis ◽

Hair Follicles ◽

Sweat Glands ◽

Sebaceous Glands ◽

Secondary Tumor ◽

Secondary Tumors ◽

Secondary Lesion ◽

Malignant Lesions ◽

Nevus Sebaceous

Abstract Introduction. Nevus sebaceous is a rare congenital hamartoma, composed of epidermis, sebaceous glands, sweat glands and hair follicles. It is possible to develop secondary tumors in the area of nevus sebaceous during the lifetime, most often after puberty. Secondary lesions are most often benign, while malignant lesions may occur but significantly less frequently. Case report. We present the case of a 21-year-old patient who came for an examination due to the appearance of a nodule in the area of a yellowish lesion on the head. The yellowish lesion was present since birth, and the nodule appeared about a year before. The dermoscopic examination of the lesion was nonspecific. The final diagnosis of eccrine poroma as a secondary lesion in nevus sebaceous was made by pathohisto-logical analysis. Conclusion. Every secondary tumor in nevus sebaceous deserves full attention, with either close follow up, or excision with pathohistological analysis.

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Four Different Tumors Arising in a Nevus Sebaceous

Case Reports in Dermatology ◽

10.1159/000445822 ◽

2016 ◽

Vol 8 (1) ◽

pp. 75-79 ◽

Cited By ~ 5

Author(s):

Takeshi Namiki ◽

Keiko Miura ◽

Makiko Ueno ◽

Yumi Arima ◽

Aya Nishizawa ◽

...

Keyword(s):

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Basal Cell ◽

Histopathological Examination ◽

Lower Portion ◽

Multiple Tumors ◽

Secondary Tumors ◽

Syringocystadenoma Papilliferum ◽

Nevus Sebaceous ◽

Black Node

Nevus sebaceous is known by its association with one or more secondary tumors, but more than three multiple tumors arising from a nevus sebaceous is extremely rare. A 67-year-old female presented with a light brown plaque on the back of her head that contained a dome-shaped black node and an erosive lesion. Histopathological examination showed atypical basaloid cells in the black node. At the periphery of that node, structures resembling follicular germs extruded from interlacing cords in the upper portion and tumor nests with sebocytes were in the lower portion. In the erosive lesion, papillated structures with an apocrine epithelium were observed. In the light brown plaque, enlargement of sebaceous lobules was noted. From those histopathological features, a diagnosis of syringocystadenoma papilliferum, sebaceoma, trichoblastoma and basal cell carcinoma arising from a nevus sebaceous was made. We discuss the rarity of multiple tumors arising from a nevus sebaceous.

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