D3 Lymph Node Dissection in Right Hemicolectomy with a No-touch Isolation Technique in Patients With Colon Cancer

2013 ◽  
Vol 56 (7) ◽  
pp. 815-824 ◽  
Author(s):  
Yukihide Kanemitsu ◽  
Koji Komori ◽  
Kenya Kimura ◽  
Tomoyuki Kato
2021 ◽  
Vol 41 (10) ◽  
pp. 5097-5106
Author(s):  
YOSUKE ATSUMI ◽  
MASAKATSU NUMATA ◽  
KEISUKE KAZAMA ◽  
SHINNOSUKE KAWAHARA ◽  
MIHWA JU ◽  
...  

2021 ◽  
Author(s):  
SK Efetov ◽  
YuE Kitsenko ◽  
DA Shchervyanina ◽  
AG Minenkova ◽  
IA Tulina ◽  
...  

2019 ◽  
Vol 34 (4) ◽  
pp. 621-628 ◽  
Author(s):  
Masakatsu Numata ◽  
Sho Sawazaki ◽  
Toru Aoyama ◽  
Hiroshi Tamagawa ◽  
Tsutomu Sato ◽  
...  

2019 ◽  
Vol 37 (4_suppl) ◽  
pp. 653-653
Author(s):  
Tomonori Akagi ◽  
Takao Hara ◽  
Masafumi Inomata ◽  
Junki Mizusawa ◽  
Hiroshi Katayama ◽  
...  

653 Background: In curative resection of sigmoid colon and rectal cancer, it is unclear whether D3 lymph node dissection preserving left colic artery (LCA) (Group A) is beneficial compared to D3 without preserving LCA (Group B) in terms of clinical outcomes. Preservation of LCA is expected to maintain blood supply which results in preventing anastomotic leakage, intestinal paralysis, and so on. Methods: The data of JCOG0404 (which is a randomized controlled trial comparing open to laparoscopic surgery for stage II/III colon cancer) were used. Eligibility criteria in JCOG0404 included histologically proven colon cancer; T3 or deeper lesion without involvement of other organs; N0-2 and M0. D3 lymph node dissection with or without preserving LCA was identified according to the photographs of the resected field collected for central surgical review in JCOG0404. The short and long-term outcomes were compared between each procedure. Results: Among all randomized 1057 patients in JCOG0404, 631 patients who received assigned sigmoid colectomy and anterior resection were included in the subgroup analysis. The number of patients were 135 in Group A and 496 in Group B. The patient backgrounds did not differ between groups. The median operative time, median blood loss, and the proportion of grade 1 or more anastomotic leakage and intestinal paralysis were not remarkably different (Group A vs. Group B: 185 min vs 186 min, 60 ml vs. 50 ml, 3.0% vs. 5.0%, and 2.2% vs. 3.8%). However, overall postoperative complication occurred more in Group B than in Group A (9.6% and 21.6%, p = 0.022). In terms of efficacy, 5-year relapse-free survival (RFS) and overall survival (OS) tended to be better in Group A than Group B (RFS: 83.7% and 80.5%, HR 1.25 (95% CI 0.79-1.96), OS: 96.3% and 91.1%, HR 2.47 (95% CI 1.13-5.40)). Conclusions: Short and long-term outcomes were better in Group A than Group B. It was considered that D3 lymph node dissection preserving LCA could be alternative treatment for D3 lymph node dissection. Clinical trial information: C000000105.


2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Jiangrui Liu ◽  
Yibin Su ◽  
Xing Liu ◽  
Jinfu Zhuang ◽  
Yuanfeng Yang ◽  
...  

Abstract Background D3 or complete mesocolic excision (CME) surgery has become a common surgical procedure for the treatment of colon cancer metastasis. Clinical misuse and overuse of lymph node dissection bring unnecessary burdens to patients. A detailed guidance for lymph node dissection in patients with T3 and T4 stage right colon cancer at different locations is urgently needed. Methods A retrospective study was performed. Patients received D3 or CME surgery were divided into ileocecal group, ascending colon group, and hepatic flexure group according to the 9th edition of the Japanese Society for Cancer of the Colon and Rectum guidelines. The distributions of lymph node metastases were analyzed according to tumor infiltration depth (T stage) and tumor location. Results The incidence of metastases in the paracolic area (or station), intermediate area, and main (or central) area was 38.4% (139/362), 12.7% (46/362), and 9.7% (35/362), respectively. The proportion of patients having No.206 and terminal ileum lymph nodes metastases was 7.7% (14/181) and 3.7% (9/244), respectively. No.206 lymph node metastasis is related to tumor location (χ2 = 7.955, p = 0.019) and degree of differentiation (χ2 = 18.99, p = 0.000), and terminal ileum lymph node metastasis is related to tumor location (χ2 = 6.273, p = 0.043). Patients with T3/T4 hepatic flexure cancer received radical right hemicolectomy in addition to No.206 lymph node dissection. Conclusion Radical right hemicolectomy and No.206 group lymph node dissection are necessary for T3 and T4 stage colon cancer therapy.


Sign in / Sign up

Export Citation Format

Share Document