Granisetron, a selective 5-HT3 antagonist, reduces L-3,4-dihydroxyphenylalanine-induced abnormal involuntary movements in the 6-hydroxydopamine-lesioned rat

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Cynthia Kwan ◽  
Imane Frouni ◽  
Dominique Bédard ◽  
Adjia Hamadjida ◽  
Philippe Huot
Keyword(s):  
Abnormal Involuntary Movements ◽  
Involuntary Movements ◽  
6 Hydroxydopamine

scholarly journals Striatal ΔFosB gene suppression inhibits the development of abnormal involuntary movements induced by L-Dopa in rats

Gene Therapy ◽  
2021 ◽  
Author(s):  
Goichi Beck ◽  
Jie Zhang ◽  
Kayoko Fong ◽  
Hideki Mochizuki ◽  
M. Maral Mouradian ◽  
...  
Keyword(s):  
Gene Suppression ◽  
Abnormal Involuntary Movements ◽  
Involuntary Movements

The Nithsdale Schizophrenia Survey V. Follow-up of Tardive Dyskinesia at3-1/2 years

1986 ◽  
Vol 149 (5) ◽  
pp. 621-623 ◽  
Author(s):  
A. D. T. Robinson ◽  
R. G. McCreadie
Keyword(s):  
Tardive Dyskinesia ◽  
Older Patients ◽  
Geographical Area ◽  
Point Prevalence ◽  
Abnormal Involuntary Movements ◽  
Involuntary Movements ◽  
Transient Feature

The point-prevalence of tardive dyskinesia in schizophrenics from a discrete geographical area (Nithsdale, in Dumfries and Galloway Region) in 1981, 1982, and 1984 was 31%, 27%, and 30% respectively. This suggests that the prevalence of tardive dyskinesia in a community of schizophrenics has reached a plateau. In 12% of patients there was persistent dyskinesia, i.e. abnormal involuntary movements were present at all three assessments. Persistent dyskinesia was more common in older patients. The severity of tardive dyskinesia fluctuated between assessments in 41 % of patients, indicating that it is only a transient feature in some cases.

Tardive Dyskinesia

1992 ◽  
Vol 160 (1) ◽  
pp. 110-112 ◽  
Author(s):  
Robertson Macpherson ◽  
Rachel Collis
Keyword(s):  
Cognitive Function ◽  
Tardive Dyskinesia ◽  
Psychiatric Hospital ◽  
Negative Symptoms ◽  
Cognitive Deficit ◽  
Defect State ◽  
Abnormal Involuntary Movements ◽  
Involuntary Movements ◽  
Short Test

Of 113 patients in long-stay wards of a psychiatric hospital, 43 had TD. Twenty-six of the 39 patients who consented to take part in the study were unaware of abnormal involuntary movements. These patients scored significantly lower on a short test of cognitive function than patients who were aware of such movements. The diagnosis of schizophrenia, perticularly the ‘defect’ state with cognitive deficit and negative symptoms, was found to be associated with lack of awareness of TD.

Effect of the selective 5-HT2A receptor antagonist EMD-281,014 on l-DOPA-induced abnormal involuntary movements in the 6-OHDA-lesioned rat

2018 ◽  
Vol 237 (1) ◽  
pp. 29-36 ◽  
Author(s):  
Imane Frouni ◽  
Cynthia Kwan ◽  
Dominique Bédard ◽  
Sébastien Belliveau ◽  
Élodie Bourgeois-Cayer ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Abnormal Involuntary Movements ◽  
Involuntary Movements
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