L-DOPA-elicited abnormal involuntary movements in the rats damaged severely in substantia nigra by 6-hydroxydopamine

Annals of Palliative Medicine ◽

10.21037/apm.2020.03.32 ◽

2020 ◽

Vol 9 (3) ◽

pp. 947-956

Author(s):

Rongfei Wang ◽

Ming Shao

Keyword(s):

Substantia Nigra ◽

Abnormal Involuntary Movements ◽

Involuntary Movements ◽

6 Hydroxydopamine

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P14 SENSITISATION IN TURNING BEHAVIOUR AND ABNORMAL INVOLUNTARY MOVEMENTS IN 6-HYDROXYDOPAMINE LESIONED RATS: INFLUENCE OF THE ENVIRONMENT IN WHICH TESTS ARE PERFORMED.

Behavioural Pharmacology ◽

10.1097/00008877-200609000-00055 ◽

2006 ◽

Vol 17 (5-6) ◽

pp. 545

Author(s):

A. Pinna ◽

S. Pontis ◽

M. Morelli

Keyword(s):

Abnormal Involuntary Movements ◽

Involuntary Movements ◽

Turning Behaviour ◽

6 Hydroxydopamine

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Selegiline increases on time without exacerbation of dyskinesia in 6-hydroxydopamine-lesioned rats displaying l-Dopa-induced wearing-off and abnormal involuntary movements

Behavioural Brain Research ◽

10.1016/j.bbr.2018.03.002 ◽

2018 ◽

Vol 347 ◽

pp. 350-359 ◽

Author(s):

Hiroko Tsunekawa ◽

Kazue Takahata ◽

Motoki Okano ◽

Toshiko Ishikawa ◽

Hiroshi Satoyoshi ◽

...

Keyword(s):

Abnormal Involuntary Movements ◽

Involuntary Movements ◽

Wearing Off ◽

6 Hydroxydopamine

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Granisetron, a selective 5-HT3 antagonist, reduces L-3,4-dihydroxyphenylalanine-induced abnormal involuntary movements in the 6-hydroxydopamine-lesioned rat

Behavioural Pharmacology ◽

10.1097/fbp.0000000000000601 ◽

2020 ◽

Vol Publish Ahead of Print ◽

Author(s):

Cynthia Kwan ◽

Imane Frouni ◽

Dominique Bédard ◽

Adjia Hamadjida ◽

Philippe Huot

Keyword(s):

Abnormal Involuntary Movements ◽

Involuntary Movements ◽

6 Hydroxydopamine

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Increased slow oscillatory activity in substantia nigra pars reticulata triggers abnormal involuntary movements in the 6-OHDA-lesioned rat in the presence of excessive extracelullar striatal dopamine

Neurobiology of Disease ◽

10.1016/j.nbd.2006.01.009 ◽

2006 ◽

Vol 22 (3) ◽

pp. 586-598 ◽

Author(s):

Wassilios Meissner ◽

Paula Ravenscroft ◽

René Reese ◽

Daniel Harnack ◽

Rudolf Morgenstern ◽

...

Keyword(s):

Substantia Nigra ◽

Striatal Dopamine ◽

Oscillatory Activity ◽

Substantia Nigra Pars Reticulata ◽

Abnormal Involuntary Movements ◽

Involuntary Movements

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Metabotropic glutamate mGluR5 receptor blockade opposes abnormal involuntary movements and the increases in glutamic acid decarboxylase mRNA levels induced by l-DOPA in striatal neurons of 6-hydroxydopamine-lesioned rats

Neuroscience ◽

10.1016/j.neuroscience.2009.07.060 ◽

2009 ◽

Vol 163 (4) ◽

pp. 1171-1180 ◽

Author(s):

N. Yamamoto ◽

J.-J. Soghomonian

Keyword(s):

Glutamic Acid ◽

Glutamic Acid Decarboxylase ◽

Acid Decarboxylase ◽

Receptor Blockade ◽

Mrna Levels ◽

Striatal Neurons ◽

Abnormal Involuntary Movements ◽

Involuntary Movements ◽

Metabotropic Glutamate ◽

6 Hydroxydopamine

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Neuroinflammation and L-dopa-induced abnormal involuntary movements in 6-hydroxydopamine-lesioned rat model of Parkinson's disease are counteracted by combined administration of a 5-HT1A/1B receptor agonist and A2A receptor antagonist

Neuropharmacology ◽

10.1016/j.neuropharm.2021.108693 ◽

2021 ◽

pp. 108693

Author(s):

Annalisa Pinna ◽

Giulia Costa ◽

Marcello Serra ◽

Liliana Contu ◽

Micaela Morelli

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Receptor Antagonist ◽

Rat Model ◽

Receptor Agonist ◽

Abnormal Involuntary Movements ◽

Involuntary Movements ◽

A2a Receptor ◽

Combined Administration ◽

6 Hydroxydopamine

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The effects of cannabinoid drugs on abnormal involuntary movements in dyskinetic and non-dyskinetic 6-hydroxydopamine lesioned rats

Brain Research ◽

10.1016/j.brainres.2010.09.086 ◽

2010 ◽

Vol 1363 ◽

pp. 40-48 ◽

Author(s):

Sinéad Walsh ◽

Adrienne M. Gorman ◽

David P. Finn ◽

Eilís Dowd

Keyword(s):

Abnormal Involuntary Movements ◽

Involuntary Movements ◽

6 Hydroxydopamine

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The effect of buspirone on amino acid release and neuronal activity in the substantia nigra pars reticulata of 6-hydroxydopamine hemilesioned dyskinetic rats

10.26226/morressier.5b31ec702afeeb001345adc2 ◽

2018 ◽

Author(s):

Sergio Vegas Suárez

Keyword(s):

Substantia Nigra ◽

Neuronal Activity ◽

Substantia Nigra Pars Reticulata ◽

Amino Acid Release ◽

Acid Release ◽

6 Hydroxydopamine

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Striatal ΔFosB gene suppression inhibits the development of abnormal involuntary movements induced by L-Dopa in rats

Gene Therapy ◽

10.1038/s41434-021-00249-7 ◽

2021 ◽

Author(s):

Goichi Beck ◽

Jie Zhang ◽

Kayoko Fong ◽

Hideki Mochizuki ◽

M. Maral Mouradian ◽

...

Keyword(s):

Gene Suppression ◽

Abnormal Involuntary Movements ◽

Involuntary Movements

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The Nithsdale Schizophrenia Survey V. Follow-up of Tardive Dyskinesia at3-1/2 years

The British Journal of Psychiatry ◽

10.1192/bjp.149.5.621 ◽

1986 ◽

Vol 149 (5) ◽

pp. 621-623 ◽

Author(s):

A. D. T. Robinson ◽

R. G. McCreadie

Keyword(s):

Tardive Dyskinesia ◽

Older Patients ◽

Geographical Area ◽

Point Prevalence ◽

Abnormal Involuntary Movements ◽

Involuntary Movements ◽

Transient Feature

The point-prevalence of tardive dyskinesia in schizophrenics from a discrete geographical area (Nithsdale, in Dumfries and Galloway Region) in 1981, 1982, and 1984 was 31%, 27%, and 30% respectively. This suggests that the prevalence of tardive dyskinesia in a community of schizophrenics has reached a plateau. In 12% of patients there was persistent dyskinesia, i.e. abnormal involuntary movements were present at all three assessments. Persistent dyskinesia was more common in older patients. The severity of tardive dyskinesia fluctuated between assessments in 41 % of patients, indicating that it is only a transient feature in some cases.

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