Are all bileaflet mechanical valves equal?

2009 ◽  
Vol 24 (2) ◽  
pp. 136-141 ◽  
Author(s):  
Michael E Halkos ◽  
John D Puskas
2007 ◽  
Vol 15 (5) ◽  
pp. 386-391 ◽  
Author(s):  
Wataru Kato ◽  
Kazuyoshi Tajima ◽  
Sachie Terasawa ◽  
Keisuke Tanaka ◽  
Akihiko Usui ◽  
...  

Frequent bleeding complications and poor long-term results have been reported after valve replacement in hemodialysis patients. We use mainly bileaflet mechanical valves with low-dose warfarin therapy (target international normalized ratio, 1.8–2.0) in such cases. Data of 27 hemodialysis patients undergoing isolated valve replacement from 1993 to 2002 were retrospectively analyzed. Bileaflet mechanical valves were selected in 23 patients and bioprostheses in 4. Those with mechanical valves were treated with mild anticoagulation therapy. There were 3 (11.1%) early deaths due to ischemic colitis, interstitial pneumonia, and ventricular arrhythmia. There were 3 late deaths and 5 bleeding complications during follow-up. The overall survival rate was 85.2% at 3 years and 72.9% at 5 years. The survival rate of patients with mechanical valves was 82.6% at 3 years and 76.7% at 5 years. One patient with a bioprosthesis experienced structural valvular deterioration after 3 years. The results demonstrate an acceptable long-term outcome. A bileaflet mechanical valve managed with mild anticoagulation therapy is a reasonable strategy for hemodialysis patients.


2001 ◽  
Vol 65 (4) ◽  
pp. 257-260 ◽  
Author(s):  
Eiki Tayama ◽  
Hiroshi Kawano ◽  
Tohru Takaseya ◽  
Ryoichi Hiratsuka ◽  
Takeshi Oda ◽  
...  

1996 ◽  
Vol 27 (2) ◽  
pp. 234 ◽  
Author(s):  
Robin Shandas ◽  
Michael Jones ◽  
David Solowiejcyk ◽  
Robert Manduley ◽  
Izumi Yamada ◽  
...  

BMJ Open ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. e047962
Author(s):  
Magnus Dalén ◽  
Michael Persson ◽  
Natalie Glaser ◽  
Ulrik Sartipy

ObjectiveBioprosthetic aortic valves with an extended subannular component, such as transcatheter valves, exert increased compression on the cardiac conduction system and increase the risk for permanent pacemaker implantation. It is unknown if the On-X mechanical prosthetic valve, which has an elongated subannular valve housing, increases the risk of permanent pacemaker implantation following aortic valve replacement.DesignObservational nationwide cohort study.SettingSwedish population-based study.ParticipantsAll patients aged 18–65 years who underwent primary mechanical aortic valve replacement in Sweden between 2005 and 2018. We used the Swedish Web system for Enhancement and Development of Evidence-based care in Heart disease Evaluated According to Recommended Therapies register and other Swedish national health-data registers.ExposurePatients implanted with an On-X valve versus patients implanted with other bileaflet mechanical valves.Primary and secondary outcome measuresPrimary outcome measure was permanent pacemaker implantation within 30 days of surgery.ResultsA total of 2602 patients were included, and 581 patients received an On-X valve and 2021 patients received a St Jude Masters/Regent (n=945) or Carbomedics Reduced valve (n=1076). In the total study population, 115 (4.4%) permanent pacemaker implantations were performed within 30 days after aortic valve replacement. In the propensity score matched population, there was no significant difference in the rate of permanent pacemaker implantation in the On-X group compared with the control group: 3.6% (95% CI: 2.4% to 5.5%) vs 4.0% (95% CI: 2.7% to 5.9%), p=0.877.ConclusionsThe On-X prosthetic heart valve was associated with a similarly low risk for permanent pacemaker implantation after aortic valve replacement compared with other conventional bileaflet mechanical valves. The On-X elongated subannular valve housing does not interfere with the cardiac conduction system.


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